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Items: 9

1.

Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters.

Jayawickrama GS, Nematollahi A, Sun G, Church WB.

PLoS One. 2018 Apr 24;13(4):e0196404. doi: 10.1371/journal.pone.0196404. eCollection 2018.

2.

Fragment Screening of Human Kynurenine Aminotransferase-II.

Jayawickrama GS, Nematollahi A, Sun G, Church WB.

SLAS Discov. 2018 Jul;23(6):511-519. doi: 10.1177/2472555218764620. Epub 2018 Mar 14.

PMID:
29537924
3.

Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives.

Jayawickrama GS, Nematollahi A, Sun G, Gorrell MD, Church WB.

Sci Rep. 2017 Dec 14;7(1):17559. doi: 10.1038/s41598-017-17979-7.

4.

Study of the Activity and Possible Mechanism of Action of a Reversible Inhibitor of Recombinant Human KAT-2: A Promising Lead in Neurodegenerative and Cognitive Disorders.

Nematollahi A, Sun G, Jayawickrama GS, Hanrahan JR, Church WB.

Molecules. 2016 Jun 29;21(7). pii: E856. doi: 10.3390/molecules21070856.

5.

Kynurenine Aminotransferase Isozyme Inhibitors: A Review.

Nematollahi A, Sun G, Jayawickrama GS, Church WB.

Int J Mol Sci. 2016 Jun 15;17(6). pii: E946. doi: 10.3390/ijms17060946. Review.

6.

Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution.

Nematollahi A, Sun G, Harrop SJ, Hanrahan JR, Church WB.

Int J Mol Sci. 2016 Mar 25;17(4):446. doi: 10.3390/ijms17040446.

7.

Expression, purification and crystallization of human kynurenine aminotransferase 2 exploiting a highly optimized codon set.

Sun G, Nematollahi A, Nadvi NA, Kwan AH, Jeffries CM, Church WB.

Protein Expr Purif. 2016 May;121:41-5. doi: 10.1016/j.pep.2016.01.004. Epub 2016 Jan 8.

PMID:
26773745
8.

Kynurenine Aminotransferases and the Prospects of Inhibitors for the Treatment of Schizophrenia.

Jayawickrama GS, Sadig RR, Sun G, Nematollahi A, Nadvi NA, Hanrahan JR, Gorrell MD, Church WB.

Curr Med Chem. 2015;22(24):2902-18. Review.

PMID:
26051411
9.

Homology modeling of human kynurenine aminotransferase III and observations on inhibitor binding using molecular docking.

Nematollahi A, Church WB, Nadvi NA, Gorrell MD, Sun G.

Cent Nerv Syst Agents Med Chem. 2014;14(1):2-9.

PMID:
24739074

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