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Items: 1 to 20 of 106


Cane toads (Rhinella marina) rely on water access, not drought tolerance, to invade xeric Australian environments.

Brusch GA 4th, Christian K, Brown GP, Shine R, DeNardo DF.

Oecologia. 2019 Feb;189(2):307-316. doi: 10.1007/s00442-018-4321-1. Epub 2018 Dec 8.


Screening and Characterization of Novel Polyesterases from Environmental Metagenomes with High Hydrolytic Activity against Synthetic Polyesters.

Hajighasemi M, Tchigvintsev A, Nocek B, Flick R, Popovic A, Hai T, Khusnutdinova AN, Brown G, Xu X, Cui H, Anstett J, Chernikova TN, Brüls T, Le Paslier D, Yakimov MM, Joachimiak A, Golyshina OV, Savchenko A, Golyshin PN, Edwards EA, Yakunin AF.

Environ Sci Technol. 2018 Nov 6;52(21):12388-12401. doi: 10.1021/acs.est.8b04252. Epub 2018 Oct 15.


Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.

Xu YF, Lu W, Chen JC, Johnson SA, Gibney PA, Thomas DG, Brown G, May AL, Campagna SR, Yakunin AF, Botstein D, Rabinowitz JD.

ACS Chem Biol. 2018 Oct 19;13(10):3011-3020. doi: 10.1021/acschembio.8b00804. Epub 2018 Oct 4.


"Zero Suicide" - A model for reducing suicide in United States behavioral healthcare.

Labouliere CD, Vasan P, Kramer A, Brown G, Green K, Rahman M, Kammer J, Finnerty M, Stanley B.

Suicidologi. 2018;23(1):22-30.


Biosynthesis and Activity of Prenylated FMN Cofactors.

Wang PH, Khusnutdinova AN, Luo F, Xiao J, Nemr K, Flick R, Brown G, Mahadevan R, Edwards EA, Yakunin AF.

Cell Chem Biol. 2018 May 17;25(5):560-570.e6. doi: 10.1016/j.chembiol.2018.02.007. Epub 2018 Mar 15.


Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

Martínez-Martínez M, Coscolín C, Santiago G, Chow J, Stogios PJ, Bargiela R, Gertler C, Navarro-Fernández J, Bollinger A, Thies S, Méndez-García C, Popovic A, Brown G, Chernikova TN, García-Moyano A, Bjerga GEK, Pérez-García P, Hai T, Del Pozo MV, Stokke R, Steen IH, Cui H, Xu X, Nocek BP, Alcaide M, Distaso M, Mesa V, Peláez AI, Sánchez J, Buchholz PCF, Pleiss J, Fernández-Guerra A, Glöckner FO, Golyshina OV, Yakimov MM, Savchenko A, Jaeger KE, Yakunin AF, Streit WR, Golyshin PN, Guallar V, Ferrer M, The Inmare Consortium.

ACS Chem Biol. 2018 Jan 19;13(1):225-234. doi: 10.1021/acschembio.7b00996. Epub 2017 Dec 20.


Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids.

Khusnutdinova AN, Flick R, Popovic A, Brown G, Tchigvintsev A, Nocek B, Correia K, Joo JC, Mahadevan R, Yakunin AF.

Biotechnol J. 2017 Nov;12(11). doi: 10.1002/biot.201600751. Epub 2017 Sep 5.


Identifying conflict potential in a coastal and marine environment using participatory mapping.

Moore SA, Brown G, Kobryn H, Strickland-Munro J.

J Environ Manage. 2017 Jul 15;197:706-718. doi: 10.1016/j.jenvman.2016.12.026. Epub 2017 Apr 24.


Understanding the effects of different social data on selecting priority conservation areas.

Karimi A, Tulloch AIT, Brown G, Hockings M.

Conserv Biol. 2017 Dec;31(6):1439-1449. doi: 10.1111/cobi.12947. Epub 2017 Jul 31.


Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families.

Popovic A, Hai T, Tchigvintsev A, Hajighasemi M, Nocek B, Khusnutdinova AN, Brown G, Glinos J, Flick R, Skarina T, Chernikova TN, Yim V, Brüls T, Paslier DL, Yakimov MM, Joachimiak A, Ferrer M, Golyshina OV, Savchenko A, Golyshin PN, Yakunin AF.

Sci Rep. 2017 Mar 8;7:44103. doi: 10.1038/srep44103.


Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies.

Kim T, Flick R, Brunzelle J, Singer A, Evdokimova E, Brown G, Joo JC, Minasov GA, Anderson WF, Mahadevan R, Savchenko A, Yakunin AF.

Appl Environ Microbiol. 2017 Mar 17;83(7). pii: e03172-16. doi: 10.1128/AEM.03172-16. Print 2017 Apr 1.


Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases.

Currie MA, Brown G, Wong A, Ohira T, Sugiyama K, Suzuki T, Yakunin AF, Jia Z.

RNA. 2017 Mar;23(3):346-354. doi: 10.1261/rna.057943.116. Epub 2016 Dec 8.


Mortality reduction in patients treated with long-term intensive lipid therapy: 25-year follow-up of the Familial Atherosclerosis Treatment Study-Observational Study.

Zhao XQ, Phan BA, Davis J, Isquith D, Dowdy AA, Boltz S, Neradilek M, Monick EA, Brockenbrough A, Hus-Frechette EE, Albers JJ, Brown BG.

J Clin Lipidol. 2016 Sep-Oct;10(5):1091-7. doi: 10.1016/j.jacl.2016.06.013. Epub 2016 Jul 9.


Arabidopsis TH2 Encodes the Orphan Enzyme Thiamin Monophosphate Phosphatase.

Mimura M, Zallot R, Niehaus TD, Hasnain G, Gidda SK, Nguyen TN, Anderson EM, Mullen RT, Brown G, Yakunin AF, de Crécy-Lagard V, Gregory JF 3rd, McCarty DR, Hanson AD.

Plant Cell. 2016 Oct;28(10):2683-2696. Epub 2016 Sep 27.


A system dynamics simulation model for sustainable water resources management and agricultural development in the Volta River Basin, Ghana.

Kotir JH, Smith C, Brown G, Marshall N, Johnstone R.

Sci Total Environ. 2016 Dec 15;573:444-457. doi: 10.1016/j.scitotenv.2016.08.081. Epub 2016 Aug 27.


Cardiac iron load and function in transfused patients treated with deferasirox (the MILE study).

Ho PJ, Tay L, Teo J, Marlton P, Grigg A, St Pierre T, Brown G, Badcock CA, Traficante R, Gervasio OL, Bowden DK.

Eur J Haematol. 2017 Feb;98(2):97-105. doi: 10.1111/ejh.12793. Epub 2016 Sep 20.


Emergency transport of stroke suspects in a rural state: opportunities for improvement.

Brown AT, Wei F, Culp WC, Brown G, Tyler R, Balamurugan A, Bianchi N.

Am J Emerg Med. 2016 Aug;34(8):1640-4. doi: 10.1016/j.ajem.2016.06.044. Epub 2016 Jun 14.


A family of metal-dependent phosphatases implicated in metabolite damage-control.

Huang L, Khusnutdinova A, Nocek B, Brown G, Xu X, Cui H, Petit P, Flick R, Zallot R, Balmant K, Ziemak MJ, Shanklin J, de Crécy-Lagard V, Fiehn O, Gregory JF 3rd, Joachimiak A, Savchenko A, Yakunin AF, Hanson AD.

Nat Chem Biol. 2016 Aug;12(8):621-7. doi: 10.1038/nchembio.2108. Epub 2016 Jun 20.


Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

Hajighasemi M, Nocek BP, Tchigvintsev A, Brown G, Flick R, Xu X, Cui H, Hai T, Joachimiak A, Golyshin PN, Savchenko A, Edwards EA, Yakunin AF.

Biomacromolecules. 2016 Jun 13;17(6):2027-39. doi: 10.1021/acs.biomac.6b00223. Epub 2016 May 2.


Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.

Kuznetsova E, Nocek B, Brown G, Makarova KS, Flick R, Wolf YI, Khusnutdinova A, Evdokimova E, Jin K, Tan K, Hanson AD, Hasnain G, Zallot R, de Crécy-Lagard V, Babu M, Savchenko A, Joachimiak A, Edwards AM, Koonin EV, Yakunin AF.

J Biol Chem. 2015 Jul 24;290(30):18678-98. doi: 10.1074/jbc.M115.657916. Epub 2015 Jun 12.

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