Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 24

1.

Approaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis.

Abdul Razzak R, Florence GJ, Gunn-Moore FJ.

Int J Mol Sci. 2019 Jun 25;20(12). pii: E3108. doi: 10.3390/ijms20123108. Review.

2.

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

Fraser AL, Menzies SK, King EFB, Tulloch LB, Gould ER, Zacharova MK, Smith TK, Florence GJ.

ACS Infect Dis. 2018 Apr 13;4(4):560-567. doi: 10.1021/acsinfecdis.7b00187. Epub 2018 Jan 19.

PMID:
29313667
3.

Direct and indirect approaches to identify drug modes of action.

Tulloch LB, Menzies SK, Coron RP, Roberts MD, Florence GJ, Smith TK.

IUBMB Life. 2018 Jan;70(1):9-22. doi: 10.1002/iub.1697. Epub 2017 Dec 6. Review.

4.

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

Tulloch LB, Menzies SK, Fraser AL, Gould ER, King EF, Zacharova MK, Florence GJ, Smith TK.

PLoS Negl Trop Dis. 2017 Sep 5;11(9):e0005886. doi: 10.1371/journal.pntd.0005886. eCollection 2017 Sep.

5.

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins.

Gould ER, King EFB, Menzies SK, Fraser AL, Tulloch LB, Zacharova MK, Smith TK, Florence GJ.

Bioorg Med Chem. 2017 Nov 15;25(22):6126-6136. doi: 10.1016/j.bmc.2017.01.021. Epub 2017 Jan 28.

PMID:
28185724
6.

Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase.

Stroek R, Ge Y, Talbot PD, Glok MK, Bernaś KE, Thomson CM, Gould ER, Alphey MS, Liu H, Florence GJ, Naismith JH, da Silva RG.

Biochemistry. 2017 Feb 7;56(5):793-803. doi: 10.1021/acs.biochem.6b01138. Epub 2017 Jan 24.

PMID:
28092443
7.

The trypanosome alternative oxidase: a potential drug target?

Menzies SK, Tulloch LB, Florence GJ, Smith TK.

Parasitology. 2018 Feb;145(2):175-183. doi: 10.1017/S0031182016002109. Epub 2016 Nov 29. Review.

PMID:
27894362
8.

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors.

Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Thomson MI, Tulloch LB, Zacharova MK, Smith TK.

ChemMedChem. 2016 Jul 19;11(14):1503-6. doi: 10.1002/cmdc.201600210. Epub 2016 Jun 10.

9.

An internal thioester in a pathogen surface protein mediates covalent host binding.

Walden M, Edwards JM, Dziewulska AM, Bergmann R, Saalbach G, Kan SY, Miller OK, Weckener M, Jackson RJ, Shirran SL, Botting CH, Florence GJ, Rohde M, Banfield MJ, Schwarz-Linek U.

Elife. 2015 Jun 2;4. doi: 10.7554/eLife.06638.

10.

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Tulloch LB, Smith TK.

ChemMedChem. 2014 Nov;9(11):2548-56. doi: 10.1002/cmdc.201402272. Epub 2014 Aug 21.

11.

Magnetic retraction of bowel by intraluminal injectable cyanoacrylate-based magnetic glue.

Wang Z, Brown A, André P, Brown SI, Florence GJ, Cuschieri A.

Biomed Res Int. 2013;2013:526512. doi: 10.1155/2013/526512. Epub 2013 Nov 12.

12.

Mucoadhesive polymer films for tissue retraction in laparoscopic surgery: Ex-vivo study on their mechanical properties.

Wang Z, Tai LR, McLean D, Wright EJ, Florence GJ, Brown SI, Andre P, Cuschieri A.

Biomed Mater Eng. 2014;24(1):445-51. doi: 10.3233/BME-130829.

PMID:
24211926
13.

Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues.

Florence GJ, Morris JC, Murray RG, Vanga RR, Osler JD, Smith TK.

Chemistry. 2013 Jun 17;19(25):8309-20. doi: 10.1002/chem.201204527. Epub 2013 Apr 29.

PMID:
23630031
14.

Synthesis of the originally proposed structure of palmerolide C.

Florence GJ, Wlochal J.

Chemistry. 2012 Nov 5;18(45):14250-4. doi: 10.1002/chem.201203067. Epub 2012 Oct 2.

PMID:
23033173
15.

Synthesis and stereochemical assignment of (+)-chamuvarinin.

Florence GJ, Morris JC, Murray RG, Osler JD, Reddy VR, Smith TK.

Org Lett. 2011 Feb 4;13(3):514-7. doi: 10.1021/ol1028699. Epub 2010 Dec 21.

16.

Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.

Florence GJ, Gardner NM, Paterson I.

Nat Prod Rep. 2008 Apr;25(2):342-75. doi: 10.1039/b705661n. Epub 2008 Feb 27. Review.

PMID:
18389141
17.

Total synthesis of (-)-reidispongiolide A, an actin-targeting macrolide isolated from the marine sponge Reidispongia coerulea.

Paterson I, Ashton K, Britton R, Cecere G, Chouraqui G, Florence GJ, Knust H, Stafford J.

Chem Asian J. 2008 Feb 1;3(2):367-87. doi: 10.1002/asia.200700357.

PMID:
18181126
18.

Total synthesis of (-)-reidispongiolide A, an actin-targeting marine macrolide.

Paterson I, Ashton K, Britton R, Cecere G, Chouraqui G, Florence GJ, Stafford J.

Angew Chem Int Ed Engl. 2007;46(32):6167-71. No abstract available.

PMID:
17615611
19.

Total synthesis and stereochemical reassignment of (+)-dolastatin 19.

Paterson I, Findlay AD, Florence GJ.

Org Lett. 2006 May 11;8(10):2131-4.

PMID:
16671799
20.

Stereocontrolled total synthesis of (-)-aurisides A and B.

Paterson I, Florence GJ, Heimann AC, Mackay AC.

Angew Chem Int Ed Engl. 2005 Feb 4;44(7):1130-3. No abstract available.

PMID:
15666414

Supplemental Content

Loading ...
Support Center