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Items: 1 to 20 of 120

1.

STING signaling and host defense against microbial infection.

Ahn J, Barber GN.

Exp Mol Med. 2019 Dec 11;51(12):1-10. doi: 10.1038/s12276-019-0333-0. Review.

2.

Editorial: Immuno-Epigenetic Markers for Infectious Diseases.

Dos Santos EJM, Barber GN, Ishak R, Vallinoto ACR.

Front Immunol. 2019 Nov 19;10:2719. doi: 10.3389/fimmu.2019.02719. eCollection 2019. No abstract available.

3.

STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity.

Falahat R, Perez-Villarroel P, Mailloux AW, Zhu G, Pilon-Thomas S, Barber GN, Mulé JJ.

Cancer Immunol Res. 2019 Nov;7(11):1837-1848. doi: 10.1158/2326-6066.CIR-19-0229. Epub 2019 Aug 28.

PMID:
31462408
4.

Brucella abortus Cyclic Dinucleotides Trigger STING-Dependent Unfolded Protein Response That Favors Bacterial Replication.

Guimarães ES, Gomes MTR, Campos PC, Mansur DS, Dos Santos AA, Harms J, Splitter G, Smith JA, Barber GN, Oliveira SC.

J Immunol. 2019 May 1;202(9):2671-2681. doi: 10.4049/jimmunol.1801233. Epub 2019 Mar 20.

PMID:
30894428
5.

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function.

Imanishi T, Unno M, Kobayashi W, Yoneda N, Matsuda S, Ikeda K, Hoshii T, Hirao A, Miyake K, Barber GN, Arita M, Ishii KJ, Akira S, Saito T.

Life Sci Alliance. 2019 Jan 25;2(1). pii: e201800282. doi: 10.26508/lsa.201800282. Print 2019 Feb.

6.

Ovarian Cancer Cells Commonly Exhibit Defective STING Signaling Which Affects Sensitivity to Viral Oncolysis.

de Queiroz NMGP, Xia T, Konno H, Barber GN.

Mol Cancer Res. 2019 Apr;17(4):974-986. doi: 10.1158/1541-7786.MCR-18-0504. Epub 2018 Dec 26.

7.

Combating herpesvirus encephalitis by potentiating a TLR3-mTORC2 axis.

Sato R, Kato A, Chimura T, Saitoh SI, Shibata T, Murakami Y, Fukui R, Liu K, Zhang Y, Arii J, Sun-Wada GH, Wada Y, Ikenoue T, Barber GN, Manabe T, Kawaguchi Y, Miyake K.

Nat Immunol. 2018 Oct;19(10):1071-1082. doi: 10.1038/s41590-018-0203-2. Epub 2018 Sep 10.

PMID:
30201994
8.

Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose.

Araujo AM, Antunes MM, Mattos MS, Diniz AB, Alvarenga DM, Nakagaki BN, Carvalho É, Lacerda VAS, Carvalho-Gontijo R, Goulart J, Mafra K, Freitas-Lopes MA, Oliveira HMC, Dutra CM, David BA, Mendes Silva A, Quesniaux V, Ryffel B, Oliveira SC, Barber GN, Mansur DS, Cunha TM, Rezende RM, Oliveira AG, Menezes GB.

Cells. 2018 Jul 27;7(8). pii: E88. doi: 10.3390/cells7080088.

9.

Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells.

Ahn J, Xia T, Rabasa Capote A, Betancourt D, Barber GN.

Cancer Cell. 2018 May 14;33(5):862-873.e5. doi: 10.1016/j.ccell.2018.03.027. Epub 2018 Apr 26.

10.

Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING.

Konno H, Chinn IK, Hong D, Orange JS, Lupski JR, Mendoza A, Pedroza LA, Barber GN.

Cell Rep. 2018 Apr 24;23(4):1112-1123. doi: 10.1016/j.celrep.2018.03.115.

11.

Oncolytic Viruses as Antigen-Agnostic Cancer Vaccines.

Russell SJ, Barber GN.

Cancer Cell. 2018 Apr 9;33(4):599-605. doi: 10.1016/j.ccell.2018.03.011. Review.

12.

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.

Takahashi A, Loo TM, Okada R, Kamachi F, Watanabe Y, Wakita M, Watanabe S, Kawamoto S, Miyata K, Barber GN, Ohtani N, Hara E.

Nat Commun. 2018 Mar 28;9(1):1249. doi: 10.1038/s41467-018-03555-8.

13.

Epidemiology, clinical features, and outcome of HTLV-1-related ATLL in an area of prevalence in the United States.

Malpica L, Pimentel A, Reis IM, Gotuzzo E, Lekakis L, Komanduri K, Harrington T, Barber GN, Ramos JC.

Blood Adv. 2018 Mar 27;2(6):607-620. doi: 10.1182/bloodadvances.2017011106.

14.

Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.

Konno H, Yamauchi S, Berglund A, Putney RM, Mulé JJ, Barber GN.

Oncogene. 2018 Apr;37(15):2037-2051. doi: 10.1038/s41388-017-0120-0. Epub 2018 Jan 25.

15.

STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis.

Ahn J, Son S, Oliveira SC, Barber GN.

Cell Rep. 2017 Dec 26;21(13):3873-3884. doi: 10.1016/j.celrep.2017.11.101.

16.

Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.

Costa Franco MM, Marim F, Guimarães ES, Assis NRG, Cerqueira DM, Alves-Silva J, Harms J, Splitter G, Smith J, Kanneganti TD, de Queiroz NMGP, Gutman D, Barber GN, Oliveira SC.

J Immunol. 2018 Jan 15;200(2):607-622. doi: 10.4049/jimmunol.1700725. Epub 2017 Dec 4.

17.

A noncanonical function of cGAMP in inflammasome priming and activation.

Swanson KV, Junkins RD, Kurkjian CJ, Holley-Guthrie E, Pendse AA, El Morabiti R, Petrucelli A, Barber GN, Benedict CA, Ting JP.

J Exp Med. 2017 Dec 4;214(12):3611-3626. doi: 10.1084/jem.20171749. Epub 2017 Oct 13.

18.

Cytoplasmic chromatin triggers inflammation in senescence and cancer.

Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL.

Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4.

19.

Ubiquitination of STING at lysine 224 controls IRF3 activation.

Ni G, Konno H, Barber GN.

Sci Immunol. 2017 May 5;2(11). pii: eaah7119. doi: 10.1126/sciimmunol.aah7119.

20.

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, von Bredow B, Evans DT, Yuan M, Parks CL, Ejima K, Allison DB, Rakasz E, Barber GN, Capuano S 3rd, Lifson JD, Desrosiers RC, Watkins DI.

PLoS Pathog. 2017 Jul 21;13(7):e1006529. doi: 10.1371/journal.ppat.1006529. eCollection 2017 Jul.

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