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Items: 1 to 20 of 28

1.

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins by JQ1 Unravels a Novel Epigenetic Modulation to Control Lipid Homeostasis.

Tonini C, Colardo M, Colella B, Di Bartolomeo S, Berardinelli F, Caretti G, Pallottini V, Segatto M.

Int J Mol Sci. 2020 Feb 14;21(4). pii: E1297. doi: 10.3390/ijms21041297.

2.

SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling Pathways.

Bottino C, Peserico A, Simone C, Caretti G.

Cancers (Basel). 2020 Jan 6;12(1). pii: E142. doi: 10.3390/cancers12010142. Review.

3.

Interplay between Metabolites and the Epigenome in Regulating Embryonic and Adult Stem Cell Potency and Maintenance.

Harvey A, Caretti G, Moresi V, Renzini A, Adamo S.

Stem Cell Reports. 2019 Oct 8;13(4):573-589. doi: 10.1016/j.stemcr.2019.09.003. Review.

4.

Metabolic Control of Stemness and Differentiation.

Moresi V, Sotiropoulos A, Caretti G, Harvey A.

Stem Cells Int. 2019 Jun 12;2019:6865956. doi: 10.1155/2019/6865956. eCollection 2019. No abstract available.

5.

SMYD3 promotes the epithelial-mesenchymal transition in breast cancer.

Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, Carra S, Cotelli F, Vitale G, Caretti G.

Nucleic Acids Res. 2019 Feb 20;47(3):1278-1293. doi: 10.1093/nar/gky1221.

6.

The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression.

Castiglioni I, Caccia R, Garcia-Manteiga JM, Ferri G, Caretti G, Molineris I, Nishioka K, Gabellini D.

Nat Commun. 2018 Nov 28;9(1):5026. doi: 10.1038/s41467-018-07313-8.

7.

Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival.

Segatto M, Fittipaldi R, Pin F, Sartori R, Dae Ko K, Zare H, Fenizia C, Zanchettin G, Pierobon ES, Hatakeyama S, Sperti C, Merigliano S, Sandri M, Filippakopoulos P, Costelli P, Sartorelli V, Caretti G.

Nat Commun. 2017 Nov 22;8(1):1707. doi: 10.1038/s41467-017-01645-7.

8.

Vitamin D and VDR in cancer cachexia and muscle regeneration.

Camperi A, Pin F, Costamagna D, Penna F, Menduina ML, Aversa Z, Zimmers T, Verzaro R, Fittipaldi R, Caretti G, Baccino FM, Muscaritoli M, Costelli P.

Oncotarget. 2017 Mar 28;8(13):21778-21793. doi: 10.18632/oncotarget.15583.

9.

Epigenetic Regulation Shapes the Stem Cells State.

Caretti G, Berghella L, Juan A, Latella L, Ryall J.

Stem Cells Int. 2016;2016:8143407. doi: 10.1155/2016/8143407. Epub 2016 Jan 24. No abstract available.

10.

A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.

Peserico A, Germani A, Sanese P, Barbosa AJ, Di Virgilio V, Fittipaldi R, Fabini E, Bertucci C, Varchi G, Moyer MP, Caretti G, Del Rio A, Simone C.

J Cell Physiol. 2015 Oct;230(10):2447-2460. doi: 10.1002/jcp.24975.

11.

The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.

Proserpio V, Fittipaldi R, Ryall JG, Sartorelli V, Caretti G.

Genes Dev. 2013 Jun 1;27(11):1299-312. doi: 10.1101/gad.217240.113.

12.

Tackling skeletal muscle cells epigenome in the next-generation sequencing era.

Fittipaldi R, Caretti G.

Comp Funct Genomics. 2012;2012:979168. doi: 10.1155/2012/979168. Epub 2012 Jun 3.

13.

In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components.

Verma R, Xu X, Jaiswal MK, Olsen C, Mears D, Caretti G, Galdzicki Z.

Toxicol Appl Pharmacol. 2011 Jun 15;253(3):178-87. doi: 10.1016/j.taap.2011.04.002. Epub 2011 Apr 14.

PMID:
21513724
14.

Phosphoryl-EZH-ion.

Caretti G, Palacios D, Sartorelli V, Puri PL.

Cell Stem Cell. 2011 Mar 4;8(3):262-5. doi: 10.1016/j.stem.2011.02.012.

15.

TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.

Palacios D, Mozzetta C, Consalvi S, Caretti G, Saccone V, Proserpio V, Marquez VE, Valente S, Mai A, Forcales SV, Sartorelli V, Puri PL.

Cell Stem Cell. 2010 Oct 8;7(4):455-69. doi: 10.1016/j.stem.2010.08.013.

16.

Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity.

Manni I, Caretti G, Artuso S, Gurtner A, Emiliozzi V, Sacchi A, Mantovani R, Piaggio G.

Mol Biol Cell. 2008 Dec;19(12):5203-13. doi: 10.1091/mbc.E08-03-0295. Epub 2008 Sep 24.

17.

MyoD acetylation influences temporal patterns of skeletal muscle gene expression.

Di Padova M, Caretti G, Zhao P, Hoffman EP, Sartorelli V.

J Biol Chem. 2007 Dec 28;282(52):37650-9. Epub 2007 Oct 27.

18.

p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation.

Jensen ED, Niu L, Caretti G, Nicol SM, Teplyuk N, Stein GS, Sartorelli V, van Wijnen AJ, Fuller-Pace FV, Westendorf JJ.

J Cell Biochem. 2008 Apr 1;103(5):1438-51.

PMID:
17960593
19.

The DEAD-box p68/p72 proteins and the noncoding RNA steroid receptor activator SRA: eclectic regulators of disparate biological functions.

Caretti G, Lei EP, Sartorelli V.

Cell Cycle. 2007 May 15;6(10):1172-6. Epub 2007 May 3. Review.

PMID:
17495528
20.

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.

Caretti G, Schiltz RL, Dilworth FJ, Di Padova M, Zhao P, Ogryzko V, Fuller-Pace FV, Hoffman EP, Tapscott SJ, Sartorelli V.

Dev Cell. 2006 Oct;11(4):547-60.

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