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Items: 1 to 20 of 62

1.

Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation.

Ferreira N, Perks KL, Rossetti G, Rudler DL, Hughes LA, Ermer JA, Scott LH, Kuznetsova I, Richman TR, Narayana VK, Abudulai LN, Shearwood AJ, Cserne Szappanos H, Tull D, Yeoh GC, Hool LC, Filipovska A, Rackham O.

EMBO J. 2019 Nov 13:e102155. doi: 10.15252/embj.2019102155. [Epub ahead of print]

PMID:
31721250
2.

Investigating targets for neuropharmacological intervention by molecular dynamics simulations.

Rossetti G, Kless A, Lai L, Outeiro TF, Carloni P.

Biochem Soc Trans. 2019 Jun 28;47(3):909-918. doi: 10.1042/BST20190048. Epub 2019 May 13. Review.

PMID:
31085614
3.

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas.

Wirthschaft P, Bode J, Soni H, Dietrich F, Krüwel T, Fischer B, Knobbe-Thomsen CB, Rossetti G, Hentschel A, Mack N, Schönig K, Breckwoldt MO, Schmandke A, Pusch S, Medenbach J, Bendszus M, Schwab ME, von Deimling A, Kool M, Herold-Mende C, Reifenberger G, Ahrends R, Tews B.

Acta Neuropathol. 2019 Aug;138(2):275-293. doi: 10.1007/s00401-019-02021-z. Epub 2019 May 6.

4.

High-throughput screening discovers antifibrotic properties of haloperidol by hindering myofibroblast activation.

Rehman M, Vodret S, Braga L, Guarnaccia C, Celsi F, Rossetti G, Martinelli V, Battini T, Long C, Vukusic K, Kocijan T, Collesi C, Ring N, Skoko N, Giacca M, Del Sal G, Confalonieri M, Raspa M, Marcello A, Myers MP, Crovella S, Carloni P, Zacchigna S.

JCI Insight. 2019 Apr 18;4(8). pii: 123987. doi: 10.1172/jci.insight.123987. eCollection 2019 Apr 18.

5.

Structural Determinants of the Prion Protein N-Terminus and Its Adducts with Copper Ions.

Sánchez-López C, Rossetti G, Quintanar L, Carloni P.

Int J Mol Sci. 2018 Dec 20;20(1). pii: E18. doi: 10.3390/ijms20010018. Review.

6.

Effect of in vivo post-translational modifications of the HMGB1 protein upon binding to platinated DNA: a molecular simulation study.

Lv WL, Arnesano F, Carloni P, Natile G, Rossetti G.

Nucleic Acids Res. 2018 Dec 14;46(22):11687-11697. doi: 10.1093/nar/gky1082.

7.

Role of Extracellular Loops and Membrane Lipids for Ligand Recognition in the Neuronal Adenosine Receptor Type 2A: An Enhanced Sampling Simulation Study.

Cao R, Giorgetti A, Bauer A, Neumaier B, Rossetti G, Carloni P.

Molecules. 2018 Oct 12;23(10). pii: E2616. doi: 10.3390/molecules23102616.

8.

Structural Prediction of the Dimeric Form of the Mammalian Translocator Membrane Protein TSPO: A Key Target for Brain Diagnostics.

Zeng J, Guareschi R, Damre M, Cao R, Kless A, Neumaier B, Bauer A, Giorgetti A, Carloni P, Rossetti G.

Int J Mol Sci. 2018 Aug 31;19(9). pii: E2588. doi: 10.3390/ijms19092588.

9.

Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z.

Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A.

EMBO Rep. 2018 Oct;19(10). pii: e46198. doi: 10.15252/embr.201846198. Epub 2018 Aug 20.

10.

Assessment of Intracellular Auto-Modification Levels of ARTD10 Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8.

Bütepage M, Krieg S, Eckei L, Li J, Rossetti G, Verheugd P, Lüscher B.

Methods Mol Biol. 2018;1813:41-63. doi: 10.1007/978-1-4939-8588-3_4.

PMID:
30097860
11.

The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain.

Reiners M, Margreiter MA, Oslender-Bujotzek A, Rossetti G, Gründer S, Schmidt A.

Mol Pharmacol. 2018 Oct;94(4):1114-1124. doi: 10.1124/mol.118.112375. Epub 2018 Jul 16.

PMID:
30012583
12.

Sustained clinical response after single course of rituximab as first-line monotherapy in adult-onset asthma and periocular xanthogranulomas syndrome associated with IgG4-related disease: A case report.

Pomponio G, Olivari D, Mattioli M, Angeletti A, Rossetti G, Goteri G, Gabrielli A.

Medicine (Baltimore). 2018 Jun;97(26):e11143. doi: 10.1097/MD.0000000000011143.

13.

Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription.

Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, Kappes F, Feederle R, Ernst S, Eckei L, Krieg S, Müller-Newen G, Rossetti G, Feijs KLH, Verheugd P, Lüscher B.

Sci Rep. 2018 Apr 30;8(1):6748. doi: 10.1038/s41598-018-25137-w.

14.

PTCD1 Is Required for 16S rRNA Maturation Complex Stability and Mitochondrial Ribosome Assembly.

Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A.

Cell Rep. 2018 Apr 3;23(1):127-142. doi: 10.1016/j.celrep.2018.03.033.

15.

Expression patterns of regulatory RNAs, including lncRNAs and tRNAs, during postnatal growth of normal and dystrophic (mdx) mouse muscles, and their response to taurine treatment.

Butchart LC, Terrill JR, Rossetti G, White R, Filipovska A, Grounds MD.

Int J Biochem Cell Biol. 2018 Jun;99:52-63. doi: 10.1016/j.biocel.2018.03.016. Epub 2018 Mar 22.

PMID:
29578051
16.

Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.

Matthes F, Massari S, Bochicchio A, Schorpp K, Schilling J, Weber S, Offermann N, Desantis J, Wanker E, Carloni P, Hadian K, Tabarrini O, Rossetti G, Krauss S.

ACS Chem Neurosci. 2018 Jun 20;9(6):1399-1408. doi: 10.1021/acschemneuro.8b00027. Epub 2018 Mar 14.

17.

Diminazene Is a Slow Pore Blocker of Acid-Sensing Ion Channel 1a (ASIC1a).

Schmidt A, Rossetti G, Joussen S, Gründer S.

Mol Pharmacol. 2017 Dec;92(6):665-675. doi: 10.1124/mol.117.110064. Epub 2017 Oct 12.

PMID:
29025967
18.

Structural Modeling of Human Prion Protein's Point Mutations.

Rossetti G, Carloni P.

Prog Mol Biol Transl Sci. 2017;150:105-122. doi: 10.1016/bs.pmbts.2017.07.001. Epub 2017 Aug 2. Review.

PMID:
28838657
19.

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.

Campaner E, Rustighi A, Zannini A, Cristiani A, Piazza S, Ciani Y, Kalid O, Golan G, Baloglu E, Shacham S, Valsasina B, Cucchi U, Pippione AC, Lolli ML, Giabbai B, Storici P, Carloni P, Rossetti G, Benvenuti F, Bello E, D'Incalci M, Cappuzzello E, Rosato A, Del Sal G.

Nat Commun. 2017 Jun 9;8:15772. doi: 10.1038/ncomms15772.

20.

Sulfoximines as ATR inhibitors: Analogs of VE-821.

Hendriks CMM, Hartkamp J, Wiezorek S, Steinkamp AD, Rossetti G, Lüscher B, Bolm C.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2659-2662. doi: 10.1016/j.bmcl.2017.04.026. Epub 2017 Apr 8.

PMID:
28479198

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