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Items: 1 to 20 of 23

1.

Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.

Naso FD, Sterbini V, Crecca E, Asteriti IA, Russo AD, Giubettini M, Cundari E, Lindon C, Rosa A, Guarguaglini G.

Cells. 2020 Feb 6;9(2). pii: E374. doi: 10.3390/cells9020374.

2.

Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling.

Janson G, Grottesi A, Pietrosanto M, Ausiello G, Guarguaglini G, Paiardini A.

PLoS Comput Biol. 2019 Dec 17;15(12):e1007219. doi: 10.1371/journal.pcbi.1007219. eCollection 2019 Dec.

3.

Actin-dependent regulation of cilia length by the inverted formin FHDC1.

Copeland SJ, McRae A, Guarguaglini G, Trinkle-Mulcahy L, Copeland JW.

Mol Biol Cell. 2018 Jul 1;29(13):1611-1627. doi: 10.1091/mbc.E18-02-0088. Epub 2018 May 9.

4.

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays.

Di Francesco L, Verrico A, Asteriti IA, Rovella P, Cirigliano P, Guarguaglini G, SchininĂ  ME, Lavia P.

Sci Rep. 2018 Jan 30;8(1):1850. doi: 10.1038/s41598-018-19351-9.

5.

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.

Asteriti IA, Daidone F, Colotti G, Rinaldo S, Lavia P, Guarguaglini G, Paiardini A.

Oncotarget. 2017 May 9;8(19):32117-32133. doi: 10.18632/oncotarget.16738.

6.

TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure.

De Santis Puzzonia M, Cozzolino AM, Grassi G, Bisceglia F, Strippoli R, Guarguaglini G, Citarella F, Sacchetti B, Tripodi M, Marchetti A, Amicone L.

PLoS One. 2016 Nov 28;11(11):e0167158. doi: 10.1371/journal.pone.0167158. eCollection 2016.

7.

NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation.

Gallini S, Carminati M, De Mattia F, Pirovano L, Martini E, Oldani A, Asteriti IA, Guarguaglini G, Mapelli M.

Curr Biol. 2016 Feb 22;26(4):458-69. doi: 10.1016/j.cub.2015.12.051. Epub 2016 Jan 28.

8.

Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly.

Asteriti IA, De Mattia F, Guarguaglini G.

Front Oncol. 2015 Dec 23;5:283. doi: 10.3389/fonc.2015.00283. eCollection 2015. Review.

9.

The centrosome: a multifaceted cellular weapon against chromosome instability.

Guarguaglini G, Cimini D.

Chromosome Res. 2016 Jan;24(1):1-4. doi: 10.1007/s10577-015-9512-6. No abstract available.

PMID:
26700187
10.

Amorphous silica nanoparticles alter microtubule dynamics and cell migration.

Gonzalez L, De Santis Puzzonia M, Ricci R, Aureli F, Guarguaglini G, Cubadda F, Leyns L, Cundari E, Kirsch-Volders M.

Nanotoxicology. 2015;9(6):729-36. doi: 10.3109/17435390.2014.969791. Epub 2014 Oct 17.

PMID:
25325157
11.

The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy.

Asteriti IA, Di Cesare E, De Mattia F, Hilsenstein V, Neumann B, Cundari E, Lavia P, Guarguaglini G.

Oncotarget. 2014 Aug 15;5(15):6229-42.

12.

Immunofluorescence methods in studies of the GTPase RAN and its effectors in interphase and in mitotic cells.

Guarguaglini G, de Turris V, Lavia P.

Methods Mol Biol. 2014;1120:241-52. doi: 10.1007/978-1-62703-791-4_16.

PMID:
24470030
13.

HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.

Rinaldo C, Moncada A, Gradi A, Ciuffini L, D'Eliseo D, Siepi F, Prodosmo A, Giorgi A, Pierantoni GM, Trapasso F, Guarguaglini G, Bartolazzi A, Cundari E, SchininĂ  ME, Fusco A, Soddu S.

Mol Cell. 2012 Jul 13;47(1):87-98. doi: 10.1016/j.molcel.2012.04.029. Epub 2012 May 31.

14.

Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastoma.

Ooi WF, Re A, Sidarovich V, Canella V, Arseni N, Adami V, Guarguaglini G, Giubettini M, Scaruffi P, Stigliani S, Lavia P, Tonini GP, Quattrone A.

Genes Chromosomes Cancer. 2012 Jun;51(6):545-56. doi: 10.1002/gcc.21940. Epub 2012 Feb 15.

PMID:
22337647
15.

Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces.

Asteriti IA, Giubettini M, Lavia P, Guarguaglini G.

Mol Cancer. 2011 Oct 19;10:131. doi: 10.1186/1476-4598-10-131.

16.

Control of Aurora-A stability through interaction with TPX2.

Giubettini M, Asteriti IA, Scrofani J, De Luca M, Lindon C, Lavia P, Guarguaglini G.

J Cell Sci. 2011 Jan 1;124(Pt 1):113-22. doi: 10.1242/jcs.075457. Epub 2010 Dec 8.

17.

Ran control of mitosis in human cells: gradients and local signals.

Roscioli E, Bolognesi A, Guarguaglini G, Lavia P.

Biochem Soc Trans. 2010 Dec;38(6):1709-14. doi: 10.1042/BST0381709.

PMID:
21118152
18.

The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?

Asteriti IA, Rensen WM, Lindon C, Lavia P, Guarguaglini G.

Biochim Biophys Acta. 2010 Dec;1806(2):230-9. doi: 10.1016/j.bbcan.2010.08.001. Epub 2010 Aug 12. Review.

PMID:
20708655
19.

Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cells.

Torosantucci L, De Luca M, Guarguaglini G, Lavia P, Degrassi F.

Mol Biol Cell. 2008 May;19(5):1873-82. doi: 10.1091/mbc.E07-10-1050. Epub 2008 Feb 20.

20.

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