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Items: 1 to 20 of 177

1.

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):248-249. doi: 10.1039/c8np90041h. Epub 2018 Nov 23.

PMID:
30468235
2.

VCE-004.8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity.

Palomares B, Ruiz-Pino F, Navarrete C, Velasco I, Sánchez-Garrido MA, Jimenez-Jimenez C, Pavicic C, Vazquez MJ, Appendino G, Bellido ML, Calzado MA, Tena-Sempere M, Muñoz E.

Sci Rep. 2018 Oct 31;8(1):16092. doi: 10.1038/s41598-018-34259-0.

3.

Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.

Minassi A, Rogati F, Cruz C, Prados ME, Galera N, Jinénez C, Appendino G, Bellido ML, Calzado MA, Caprioglio D, Muñoz E.

J Nat Prod. 2018 Oct 26;81(10):2235-2243. doi: 10.1021/acs.jnatprod.8b00514. Epub 2018 Oct 10.

PMID:
30350996
4.

The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders.

Río CD, Millán E, García V, Appendino G, DeMesa J, Muñoz E.

Biochem Pharmacol. 2018 Nov;157:122-133. doi: 10.1016/j.bcp.2018.08.022. Epub 2018 Aug 20. Review.

PMID:
30138623
5.

Iodine-mediated cyclization of cannabigerol (CBG) expands the cannabinoid biological and chemical space.

Lopatriello A, Caprioglio D, Minassi A, Schiano Moriello A, Formisano C, De Petrocellis L, Appendino G, Taglialatela-Scafati O.

Bioorg Med Chem. 2018 Aug 15;26(15):4532-4536. doi: 10.1016/j.bmc.2018.07.044. Epub 2018 Jul 27.

PMID:
30077611
6.

EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis.

García-Martín A, Garrido-Rodríguez M, Navarrete C, Del Río C, Bellido ML, Appendino G, Calzado MA, Muñoz E.

Biochem Pharmacol. 2018 Nov;157:304-313. doi: 10.1016/j.bcp.2018.07.047. Epub 2018 Aug 2.

PMID:
30076848
7.

VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways.

Del Rio C, Cantarero I, Palomares B, Gómez-Cañas M, Fernández-Ruiz J, Pavicic C, García-Martín A, Luz Bellido M, Ortega-Castro R, Pérez-Sánchez C, López-Pedrera C, Appendino G, Calzado MA, Muñoz E.

Br J Pharmacol. 2018 Oct;175(19):3813-3831. doi: 10.1111/bph.14450. Epub 2018 Aug 23.

PMID:
30033591
8.

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF.

Nat Prod Rep. 2019 Jan 1;36(1):35-107. doi: 10.1039/c7np00064b. Epub 2018 Jul 13. Erratum in: Nat Prod Rep. 2018 Nov 23;:.

9.

Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts.

Perini M, Paolini M, Camin F, Appendino G, Vitulo F, De Combarieu E, Sardone N, Martinelli EM, Pace R.

Fitoterapia. 2018 Jun;127:15-19. doi: 10.1016/j.fitote.2018.04.011. Epub 2018 Apr 22.

PMID:
29689331
10.

Reprint of: Amorfrutin-type phytocannabinoids from Helichrysum umbraculigerum.

Pollastro F, De Petrocellis L, Schiano-Moriello A, Chianese G, Heyman H, Appendino G, Taglialatela-Scafati O.

Fitoterapia. 2018 Apr;126:35-39. doi: 10.1016/j.fitote.2018.04.002. Epub 2018 Apr 11. No abstract available.

PMID:
29655820
11.

Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy.

Navarrete C, Carrillo-Salinas F, Palomares B, Mecha M, Jiménez-Jiménez C, Mestre L, Feliú A, Bellido ML, Fiebich BL, Appendino G, Calzado MA, Guaza C, Muñoz E.

J Neuroinflammation. 2018 Mar 1;15(1):64. doi: 10.1186/s12974-018-1103-y.

12.

Iodine-Promoted Aromatization of p-Menthane-Type Phytocannabinoids.

Pollastro F, Caprioglio D, Marotta P, Moriello AS, De Petrocellis L, Taglialatela-Scafati O, Appendino G.

J Nat Prod. 2018 Mar 23;81(3):630-633. doi: 10.1021/acs.jnatprod.7b00946. Epub 2017 Dec 14.

PMID:
29240420
13.

A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin.

Almeida A, Dong L, Khakimov B, Bassard JE, Moses T, Lota F, Goossens A, Appendino G, Bak S.

Plant Physiol. 2018 Feb;176(2):1469-1484. doi: 10.1104/pp.17.01369. Epub 2017 Dec 4.

14.

Amorfrutin-type phytocannabinoids from Helichrysum umbraculigerum.

Pollastro F, De Petrocellis L, Schiano-Moriello A, Chianese G, Heyman H, Appendino G, Taglialatela-Scafati O.

Fitoterapia. 2017 Nov;123:13-17. doi: 10.1016/j.fitote.2017.09.010. Epub 2017 Sep 20. No abstract available. Corrected and republished in: Fitoterapia. 2018 Apr;126:35-39.

PMID:
28941742
15.

Tetrahydrocannabinolic acid is a potent PPARγ agonist with neuroprotective activity.

Nadal X, Del Río C, Casano S, Palomares B, Ferreiro-Vera C, Navarrete C, Sánchez-Carnerero C, Cantarero I, Bellido ML, Meyer S, Morello G, Appendino G, Muñoz E.

Br J Pharmacol. 2017 Dec;174(23):4263-4276. doi: 10.1111/bph.14019. Epub 2017 Nov 2.

16.

An improved preparation of phorbol from croton oil.

Pagani A, Gaeta S, Savchenko AI, Williams CM, Appendino G.

Beilstein J Org Chem. 2017 Jul 11;13:1361-1367. doi: 10.3762/bjoc.13.133. eCollection 2017.

17.

Electrophilic Triterpenoid Enones: A Comparative Thiol-Trapping and Bioactivity Study.

Del Prete D, Taglialatela-Scafati O, Minassi A, Sirignano C, Cruz C, Bellido ML, Muñoz E, Appendino G.

J Nat Prod. 2017 Aug 25;80(8):2276-2283. doi: 10.1021/acs.jnatprod.7b00271. Epub 2017 Jul 28.

PMID:
28753294
18.

The reaction of cinnamaldehyde and cinnam(o)yl derivatives with thiols.

Autelitano A, Minassi A, Pagani A, Taglialatela-Scafati O, Appendino G.

Acta Pharm Sin B. 2017 Jul;7(4):523-526. doi: 10.1016/j.apsb.2017.06.005. Epub 2017 Jul 8.

19.

The anti-migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel.

Benemei S, De Logu F, Li Puma S, Marone IM, Coppi E, Ugolini F, Liedtke W, Pollastro F, Appendino G, Geppetti P, Materazzi S, Nassini R.

Br J Pharmacol. 2017 Sep;174(17):2897-2911. doi: 10.1111/bph.13917. Epub 2017 Jul 20.

20.

Carbonyl Activation in Electrophilic Polyene Cyclizations: A Toolbox for the Design of Isoprenoid Libraries.

Minassi A, Pollastro F, Chianese G, Caprioglio D, Taglialatela-Scafati O, Appendino G.

Angew Chem Int Ed Engl. 2017 Jun 26;56(27):7935-7938. doi: 10.1002/anie.201703455. Epub 2017 Jun 5.

PMID:
28488372

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