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Items: 18


Induced Pluripotent Stem Cell-Derived Red Blood Cells and Platelet Concentrates: From Bench to Bedside.

Focosi D, Amabile G.

Cells. 2017 Dec 27;7(1). pii: E2. doi: 10.3390/cells7010002. Review.


The second hit of DNA methylation.

Di Ruscio A, Welner RS, Tenen DG, Amabile G.

Mol Cell Oncol. 2015 Oct 29;3(3):e1093690. doi: 10.1080/23723556.2015.1093690. eCollection 2016 May.


SALL4, the missing link between stem cells, development and cancer.

Tatetsu H, Kong NR, Chong G, Amabile G, Tenen DG, Chai L.

Gene. 2016 Jun 15;584(2):111-9. doi: 10.1016/j.gene.2016.02.019. Epub 2016 Feb 16. Review.


Dissecting the role of aberrant DNA methylation in human leukaemia.

Amabile G, Di Ruscio A, Müller F, Welner RS, Yang H, Ebralidze AK, Zhang H, Levantini E, Qi L, Martinelli G, Brummelkamp T, Le Beau MM, Figueroa ME, Bock C, Tenen DG.

Nat Commun. 2015 May 22;6:7091. doi: 10.1038/ncomms8091.


Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cells.

Welner RS, Amabile G, Bararia D, Czibere A, Yang H, Zhang H, Pontes LL, Ye M, Levantini E, Di Ruscio A, Martinelli G, Tenen DG.

Cancer Cell. 2015 May 11;27(5):671-81. doi: 10.1016/j.ccell.2015.04.004.


Notch inhibition allows oncogene-independent generation of iPS cells.

Ichida JK, Tcw J, Williams LA, Carter AC, Shi Y, Moura MT, Ziller M, Singh S, Amabile G, Bock C, Umezawa A, Rubin LL, Bradner JE, Akutsu H, Meissner A, Eggan K.

Nat Chem Biol. 2014 Aug;10(8):632-639. doi: 10.1038/nchembio.1552. Epub 2014 Jun 22. Erratum in: Nat Chem Biol. 2014 Dec;10(12):1074. T C W, Julia [corrected to TCW, Julia].


Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG.

Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Erratum in: Cancer Cell. 2014 Feb 10;25(2):257. Diruscio, Annalisa [corrected to Di Ruscio, Annalisa].


DNMT1-interacting RNAs block gene-specific DNA methylation.

Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Alò F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG.

Nature. 2013 Nov 21;503(7476):371-6. doi: 10.1038/nature12598. Epub 2013 Oct 9.


C/EBPα is required for development of dendritic cell progenitors.

Welner RS, Bararia D, Amabile G, Czibere A, Benoukraf T, Bach C, Wansa KD, Ye M, Zhang H, Iino T, Hetherington CJ, Akashi K, Tenen DG.

Blood. 2013 May 16;121(20):4073-81. doi: 10.1182/blood-2012-10-463448. Epub 2013 Apr 1.


C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence.

Ye M, Zhang H, Amabile G, Yang H, Staber PB, Zhang P, Levantini E, Alberich-Jordà M, Zhang J, Kawasaki A, Tenen DG.

Nat Cell Biol. 2013 Apr;15(4):385-94. doi: 10.1038/ncb2698. Epub 2013 Mar 17.


In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells.

Amabile G, Welner RS, Nombela-Arrieta C, D'Alise AM, Di Ruscio A, Ebralidze AK, Kraytsberg Y, Ye M, Kocher O, Neuberg DS, Khrapko K, Silberstein LE, Tenen DG.

Blood. 2013 Feb 21;121(8):1255-64. doi: 10.1182/blood-2012-06-434407. Epub 2012 Dec 4.


C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia.

Alberich-Jordà M, Wouters B, Balastik M, Shapiro-Koss C, Zhang H, Di Ruscio A, Radomska HS, Ebralidze AK, Amabile G, Ye M, Zhang J, Lowers I, Avellino R, Melnick A, Figueroa ME, Valk PJ, Delwel R, Tenen DG.

J Clin Invest. 2012 Dec;122(12):4490-504. doi: 10.1172/JCI65102. Epub 2012 Nov 19. Erratum in: J Clin Invest. 2013 Jan 2;123(1):526. DiRuscio, Annalisa [corrected to Di Ruscio, Annalisa].


RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG.

EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285.


Induced pluripotent stem cells: current progress and potential for regenerative medicine.

Amabile G, Meissner A.

Trends Mol Med. 2009 Feb;15(2):59-68. doi: 10.1016/j.molmed.2008.12.003. Epub 2009 Jan 21. Review.


Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells.

D'Alise AM, Amabile G, Iovino M, Di Giorgio FP, Bartiromo M, Sessa F, Villa F, Musacchio A, Cortese R.

Mol Cancer Ther. 2008 May;7(5):1140-9. doi: 10.1158/1535-7163.MCT-07-2051.


The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.

Ghinassi B, Sanchez M, Martelli F, Amabile G, Vannucchi AM, Migliaccio G, Orkin SH, Migliaccio AR.

Blood. 2007 Feb 15;109(4):1460-71. Epub 2006 Oct 12.


An autocrine loop involving ret and glial cell-derived neurotrophic factor mediates retinoic acid-induced neuroblastoma cell differentiation.

Cerchia L, D'Alessio A, Amabile G, Duconge F, Pestourie C, Tavitian B, Libri D, de Franciscis V.

Mol Cancer Res. 2006 Jul;4(7):481-8.


Isolation of TPO-dependent subclones from the multipotent 32D cell line.

Amabile G, Di Noia A, Alfani E, Vannucchi AM, Sanchez M, Bosco D, Migliaccio AR, Migliaccio G.

Blood Cells Mol Dis. 2005 Sep-Oct;35(2):241-52.


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