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Items: 6


New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative.

Rossino G, Orellana I, Caballero J, Schepmann D, Wünsch B, Rui M, Rossi D, González-Avendaño M, Collina S, Vergara-Jaque A.

J Chem Inf Model. 2020 Feb 24;60(2):756-765. doi: 10.1021/acs.jcim.9b00649. Epub 2019 Dec 20.


Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-33.

Velázquez-Libera JL, Rossino G, Navarro-Retamal C, Collina S, Caballero J.

Front Chem. 2019 Jul 11;7:496. doi: 10.3389/fchem.2019.00496. eCollection 2019.


Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A, Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B, Liedl KR, Cavaletti G, Pace V, Urban E, Collina S.

Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010. Epub 2018 Sep 8.


PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds.

Rossino G, Raimondi MV, Rui M, Di Giacomo M, Rossi D, Collina S.

Molecules. 2018 Mar 28;23(4). pii: E775. doi: 10.3390/molecules23040775.


Approaches for multi-gram scale isolation of enantiomers for drug discovery.

Rossi D, Tarantino M, Rossino G, Rui M, Juza M, Collina S.

Expert Opin Drug Discov. 2017 Dec;12(12):1253-1269. doi: 10.1080/17460441.2017.1383981. Epub 2017 Oct 3. Review.


PKC in Regenerative Therapy: New Insights for Old Targets.

Rui M, Nasti R, Bignardi E, Della Volpe S, Rossino G, Rossi D, Collina S.

Pharmaceuticals (Basel). 2017 May 18;10(2). pii: E46. doi: 10.3390/ph10020046. Review.

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