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What do laypeople consider 'medication' and are they aware of modulators of a drug's effects?

Send AFJ, Bittmann JA, Dyckhoff G, Haefeli WE, Seidling HM.

Eur J Hosp Pharm Sci Pract. 2018 Jul;25(4):218-221. doi: 10.1136/ejhpharm-2016-001086. Epub 2016 Nov 1.


DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.

Weigel C, Chaisaingmongkol J, Assenov Y, Kuhmann C, Winkler V, Santi I, Bogatyrova O, Kaucher S, Bermejo JL, Leung SY, Chan TL, Lasitschka F, Bohrer MH, Marx A, Haußen RH, Herold-Mende C, Dyckhoff G, Boukamp P, Delank KW, Hörmann K, Lippert BM, Baier G, Dietz A, Oakes CC, Plass C, Becher H, Schmezer P, Ramroth H, Popanda O.

Clin Epigenetics. 2019 May 3;11(1):67. doi: 10.1186/s13148-019-0666-5.


Differential Activation of ERK Signaling in HPV-Related Oropharyngeal Squamous Cell Carcinoma.

Rong C, Muller M, Flechtenmacher C, Holzinger D, Dyckhoff G, Bulut OC, Horn D, Plinkert P, Hess J, Affolter A.

Cancers (Basel). 2019 Apr 25;11(4). pii: E584. doi: 10.3390/cancers11040584.


Cortactin expression: Association with disease progression and survival in oral squamous cell carcinoma.

Horn D, Gross M, Dyckhoff G, Fuchs J, Grabe N, Weichert W, Herpel E, Herold-Mende C, Lichter P, Hoffmann J, Hess J, Freier K.

Head Neck. 2018 Dec;40(12):2685-2694. doi: 10.1002/hed.25515. Epub 2018 Nov 20.


Totale Laryngektomie: Wundinfektionen sind bei Diabetespatienten häufiger.

Dyckhoff G.

Laryngorhinootologie. 2018 May;97(5):301-302. doi: 10.1055/s-0043-121849. Epub 2018 May 2. German.


Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway.

Rigalli JP, Reichel M, Tocchetti GN, Reuter T, Dyckhoff G, Herold-Mende C, Weiss J.

Cancer Lett. 2018 Aug 1;428:69-76. doi: 10.1016/j.canlet.2018.04.036. Epub 2018 Apr 30.


Comparison of the RGD Motif-Containing αvβ6 Integrin-Binding Peptides SFLAP3 and SFITGv6 for Diagnostic Application in HNSCC.

Roesch S, Lindner T, Sauter M, Loktev A, Flechsig P, Müller M, Mier W, Warta R, Dyckhoff G, Herold-Mende C, Haberkorn U, Altmann A.

J Nucl Med. 2018 Nov;59(11):1679-1685. doi: 10.2967/jnumed.118.210013. Epub 2018 Apr 19.


The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma.

Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J.

PLoS One. 2018 Feb 22;13(2):e0193242. doi: 10.1371/journal.pone.0193242. eCollection 2018.


Upregulation of pAKT(Ser473) expression in progression of HPV-positive oropharyngeal squamous cell carcinoma.

Horn D, Freudlsperger C, Holzinger D, Kunzmann K, Plinkert P, Dyckhoff G, Hoffmann J, Freier K, Hess J.

Head Neck. 2017 Dec;39(12):2397-2405. doi: 10.1002/hed.24910. Epub 2017 Sep 25.


A change in the study evaluation paradigm reveals that larynx preservation compromises survival in T4 laryngeal cancer patients.

Dyckhoff G, Plinkert PK, Ramroth H.

BMC Cancer. 2017 Sep 1;17(1):609. doi: 10.1186/s12885-017-3608-7.


Identification of a Novel ITGαvβ6-Binding Peptide Using Protein Separation and Phage Display.

Altmann A, Sauter M, Roesch S, Mier W, Warta R, Debus J, Dyckhoff G, Herold-Mende C, Haberkorn U.

Clin Cancer Res. 2017 Aug 1;23(15):4170-4180. doi: 10.1158/1078-0432.CCR-16-3217. Epub 2017 May 3.


Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study.

Schroeder L, Boscolo-Rizzo P, Dal Cin E, Romeo S, Baboci L, Dyckhoff G, Hess J, Lucena-Porcel C, Byl A, Becker N, Alemany L, Castellsagué X, Quer M, León X, Wiesenfarth M, Pawlita M, Holzinger D.

Eur J Cancer. 2017 Mar;74:73-81. doi: 10.1016/j.ejca.2016.12.020. Epub 2017 Feb 10.


Sensitivity and specificity of antibodies against HPV16 E6 and other early proteins for the detection of HPV16-driven oropharyngeal squamous cell carcinoma.

Holzinger D, Wichmann G, Baboci L, Michel A, Höfler D, Wiesenfarth M, Schroeder L, Boscolo-Rizzo P, Herold-Mende C, Dyckhoff G, Boehm A, Del Mistro A, Bosch FX, Dietz A, Pawlita M, Waterboer T.

Int J Cancer. 2017 Jun 15;140(12):2748-2757. doi: 10.1002/ijc.30697. Epub 2017 Apr 4.


Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma.

Tawk B, Schwager C, Deffaa O, Dyckhoff G, Warta R, Linge A, Krause M, Weichert W, Baumann M, Herold-Mende C, Debus J, Abdollahi A.

Radiother Oncol. 2016 Feb;118(2):350-8. doi: 10.1016/j.radonc.2015.11.027. Epub 2015 Dec 19.


Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma.

Reuter T, Warta R, Theile D, Meid AD, Rigalli JP, Mogler C, Herpel E, Grabe N, Lahrmann B, Plinkert PK, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J.

Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388(11):1141-50. doi: 10.1007/s00210-015-1150-1. Epub 2015 Jul 4.


Association of history of allergies and influenza-like infections with laryngeal cancer in a case-control study.

Filippidis FT, Schwartz SM, Becker N, Dyckhoff G, Kirschfink M, Dietz A, Becher H, Ramroth H.

Eur Arch Otorhinolaryngol. 2015 Aug;272(8):2063-9. doi: 10.1007/s00405-015-3528-6. Epub 2015 Jan 30.


An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo.

Kiesgen S, Arndt MAE, Körber C, Arnold U, Weber T, Halama N, Keller A, Bötticher B, Schlegelmilch A, Liebers N, Cremer M, Herold-Mende C, Dyckhoff G, Federspil PA, Jensen AD, Jäger D, Kontermann RE, Mier W, Krauss J.

Cancer Lett. 2015 Feb 1;357(1):364-373. doi: 10.1016/j.canlet.2014.11.054. Epub 2014 Nov 27.


Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma.

Freudlsperger C, Horn D, Weißfuß S, Weichert W, Weber KJ, Saure D, Sharma S, Dyckhoff G, Grabe N, Plinkert P, Hoffmann J, Freier K, Hess J.

Int J Cancer. 2015 Jun 15;136(12):2775-85. doi: 10.1002/ijc.29328. Epub 2014 Nov 26.


A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody-ribonuclease fusion protein targeting the EGF receptor.

Kiesgen S, Liebers N, Cremer M, Arnold U, Weber T, Keller A, Herold-Mende C, Dyckhoff G, Jäger D, Kontermann RE, Arndt MA, Krauss J.

Protein Eng Des Sel. 2014 Oct;27(10):331-7. doi: 10.1093/protein/gzu040.


Acinar cell carcinomas of the pancreas: a molecular analysis in a series of 57 cases.

Bergmann F, Aulmann S, Sipos B, Kloor M, von Heydebreck A, Schweipert J, Harjung A, Mayer P, Hartwig W, Moldenhauer G, Capper D, Dyckhoff G, Freier K, Herpel E, Schleider A, Schirmacher P, Mechtersheimer G, Klöppel G, Bläker H.

Virchows Arch. 2014 Dec;465(6):661-72. doi: 10.1007/s00428-014-1657-8. Epub 2014 Oct 9.


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