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Items: 1 to 20 of 94

1.

Epigenetic Changes as a Target in Aging Haematopoietic Stem Cells and Age-Related Malignancies.

Buisman SC, de Haan G.

Cells. 2019 Aug 10;8(8). pii: E868. doi: 10.3390/cells8080868. Review.

2.

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.

Ackermann T, Hartleben G, Müller C, Mastrobuoni G, Groth M, Sterken BA, Zaini MA, Youssef SA, Zuidhof HR, Krauss SR, Kortman G, de Haan G, de Bruin A, Wang ZQ, Platzer M, Kempa S, Calkhoven CF.

Commun Biol. 2019 Jun 14;2:208. doi: 10.1038/s42003-019-0461-z. eCollection 2019.

3.

MiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clones.

Wojtowicz EE, Broekhuis MJC, Weersing E, Dinitzen A, Verovskaya E, Ausema A, Ritsema M, Zwart E, de Haan G, Bystrykh LV.

Sci Rep. 2019 Mar 18;9(1):4785. doi: 10.1038/s41598-019-38503-z.

4.

CBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions.

Jung J, Buisman SC, Weersing E, Dethmers-Ausema A, Zwart E, Schepers H, Dekker MR, Lazare SS, Hammerl F, Skokova Y, Kooistra SM, Klauke K, Poot RA, Bystrykh LV, de Haan G.

Cell Rep. 2019 Feb 12;26(7):1906-1918.e8. doi: 10.1016/j.celrep.2019.01.050.

5.

Epigenetic age-predictor for mice based on three CpG sites.

Han Y, Eipel M, Franzen J, Sakk V, Dethmers-Ausema B, Yndriago L, Izeta A, de Haan G, Geiger H, Wagner W.

Elife. 2018 Aug 24;7. pii: e37462. doi: 10.7554/eLife.37462.

6.

Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow.

Geerman S, Brasser G, Bhushal S, Salerno F, Kragten NA, Hoogenboezem M, de Haan G, Wolkers MC, Pascutti MF, Nolte MA.

Haematologica. 2018 Jun;103(6):e230-e233. doi: 10.3324/haematol.2017.169516. Epub 2018 Feb 22. No abstract available.

7.

Regenerative medicine funding policies in Europe and The Netherlands.

de Haan G, de Crom R, Dzierzak E, Mummery C.

NPJ Regen Med. 2017 Jan 5;2:1. doi: 10.1038/s41536-016-0006-8. eCollection 2017. Review. No abstract available.

8.

Left or right? Directions to stem cell engraftment.

Belderbos ME, Bystrykh L, de Haan G.

J Exp Med. 2018 Jan 2;215(1):13-15. doi: 10.1084/jem.20171904. Epub 2017 Nov 28.

9.

Aging of hematopoietic stem cells.

de Haan G, Lazare SS.

Blood. 2018 Feb 1;131(5):479-487. doi: 10.1182/blood-2017-06-746412. Epub 2017 Nov 15. Review.

10.

Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.

Martín-Pardillos A, Tsaalbi-Shtylik A, Chen S, Lazare S, van Os RP, Dethmers-Ausema A, Fakouri NB, Bosshard M, Aprigliano R, van Loon B, Salvatori DCF, Hashimoto K, Dingemanse-van der Spek C, Moriya M, Rasmussen LJ, de Haan G, Raaijmakers MHGP, de Wind N.

Blood. 2017 Sep 28;130(13):1523-1534. doi: 10.1182/blood-2017-01-764274. Epub 2017 Aug 21. Erratum in: Blood. 2018 Feb 8;131(6):710.

11.

Lifelong dietary intervention does not affect hematopoietic stem cell function.

Lazare S, Ausema A, Reijne AC, van Dijk G, van Os R, de Haan G.

Exp Hematol. 2017 Sep;53:26-30. doi: 10.1016/j.exphem.2017.06.002. Epub 2017 Jun 16.

PMID:
28625745
12.

Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding.

Belderbos ME, Koster T, Ausema B, Jacobs S, Sowdagar S, Zwart E, de Bont E, de Haan G, Bystrykh LV.

Blood. 2017 Jun 15;129(24):3210-3220. doi: 10.1182/blood-2016-12-758250. Epub 2017 Apr 10.

13.

Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors.

Wojtowicz EE, Lechman ER, Hermans KG, Schoof EM, Wienholds E, Isserlin R, van Veelen PA, Broekhuis MJ, Janssen GM, Trotman-Grant A, Dobson SM, Krivdova G, Elzinga J, Kennedy J, Gan OI, Sinha A, Ignatchenko V, Kislinger T, Dethmers-Ausema B, Weersing E, Alemdehy MF, de Looper HW, Bader GD, Ritsema M, Erkeland SJ, Bystrykh LV, Dick JE, de Haan G.

Cell Stem Cell. 2016 Sep 1;19(3):383-96. doi: 10.1016/j.stem.2016.06.008. Epub 2016 Jul 14.

14.

Hematopoiesis during development, aging, and disease.

Jung J, Buisman S, de Haan G.

Exp Hematol. 2016 Aug;44(8):689-95. doi: 10.1016/j.exphem.2016.05.007. Epub 2016 May 25. Review.

PMID:
27235755
15.

Epigenetic perturbations in aging stem cells.

Krauss SR, de Haan G.

Mamm Genome. 2016 Aug;27(7-8):396-406. doi: 10.1007/s00335-016-9645-8. Epub 2016 May 26. Review.

16.

Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands.

Pringle S, Maimets M, van der Zwaag M, Stokman MA, van Gosliga D, Zwart E, Witjes MJ, de Haan G, van Os R, Coppes RP.

Stem Cells. 2016 Mar;34(3):640-52. doi: 10.1002/stem.2278.

17.

The European Hematology Association Roadmap for European Hematology Research: a consensus document.

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TD, Eichinger S, Fibbe W, Green T, de Haas F, Iolascon A, Jaffredo T, Rodeghiero F, Salles G, Schuringa JJ; EHA Roadmap for European Hematology Research.

Haematologica. 2016 Feb;101(2):115-208. doi: 10.3324/haematol.2015.136739. Epub 2016 Jan 27.

18.

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals.

Maimets M, Rocchi C, Bron R, Pringle S, Kuipers J, Giepmans BN, Vries RG, Clevers H, de Haan G, van Os R, Coppes RP.

Stem Cell Reports. 2016 Jan 12;6(1):150-62. doi: 10.1016/j.stemcr.2015.11.009. Epub 2015 Dec 24.

19.

Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus.

Brugman MH, Wiekmeijer AS, van Eggermond M, Wolvers-Tettero I, Langerak AW, de Haas EF, Bystrykh LV, van Rood JJ, de Haan G, Fibbe WE, Staal FJ.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E6020-7. doi: 10.1073/pnas.1519118112. Epub 2015 Oct 19.

20.

Stem Cells and Aging: What's Next?

Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Muñoz-Cánoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y.

Cell Stem Cell. 2015 Jun 4;16(6):578-81. No abstract available.

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