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Items: 1 to 20 of 67

1.

Outbreaks of histoplasmosis: The spores set sail.

Deepe GS Jr.

PLoS Pathog. 2018 Sep 13;14(9):e1007213. doi: 10.1371/journal.ppat.1007213. eCollection 2018 Sep. No abstract available.

2.

Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis.

Kyrmizi I, Ferreira H, Carvalho A, Figueroa JAL, Zarmpas P, Cunha C, Akoumianaki T, Stylianou K, Deepe GS Jr, Samonis G, Lacerda JF, Campos A Jr, Kontoyiannis DP, Mihalopoulos N, Kwon-Chung KJ, El-Benna J, Valsecchi I, Beauvais A, Brakhage AA, Neves NM, Latge JP, Chamilos G.

Nat Microbiol. 2018 Jul;3(7):791-803. doi: 10.1038/s41564-018-0167-x. Epub 2018 May 30.

PMID:
29849062
3.

Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice.

Deepe GS Jr, Buesing WR, Ostroff GR, Abraham A, Specht CA, Huang H, Levitz SM.

Vaccine. 2018 May 31;36(23):3359-3367. doi: 10.1016/j.vaccine.2018.04.047. Epub 2018 May 2.

PMID:
29729993
4.

Tumor Necrosis Factor Alpha Antagonism Reveals a Gut/Lung Axis That Amplifies Regulatory T Cells in a Pulmonary Fungal Infection.

Tweedle JL, Deepe GS Jr.

Infect Immun. 2018 May 22;86(6). pii: e00109-18. doi: 10.1128/IAI.00109-18. Print 2018 Jun.

PMID:
29581197
5.

Metallothioneins: Emerging Modulators in Immunity and Infection.

Subramanian Vignesh K, Deepe GS Jr.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2197. doi: 10.3390/ijms18102197. Review.

6.

Investigation of an optimal cell lysis method for the study of the zinc metalloproteome of Histoplasma capsulatum.

Donnell AM, Lewis S, Abraham S, Subramanian K, Figueroa JL, Deepe GS Jr, Vonderheide AP.

Anal Bioanal Chem. 2017 Oct;409(26):6163-6172. doi: 10.1007/s00216-017-0556-7. Epub 2017 Aug 12.

PMID:
28801743
7.

Antifungal Activity of the Lipophilic Antioxidant Ferrostatin-1.

Horwath MC, Bell-Horwath TR, Lescano V, Krishnan K, Merino EJ, Deepe GS Jr.

Chembiochem. 2017 Oct 18;18(20):2069-2078. doi: 10.1002/cbic.201700105. Epub 2017 Sep 1.

PMID:
28783875
8.

Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells.

Nanjappa SG, McDermott AJ, Fites JS, Galles K, Wüthrich M, Deepe GS Jr, Klein BS.

PLoS Pathog. 2017 May 22;13(5):e1006356. doi: 10.1371/journal.ppat.1006356. eCollection 2017 May.

9.

Elevated Circulating Concentrations of Interferon-Gamma in Latent Tuberculosis Infection.

Huaman MA, Deepe GS Jr, Fichtenbaum CJ.

Pathog Immun. 2016 Fall-Winter;1(2):291-303.

10.

Impact of HIF-1α and hypoxia on fungal growth characteristics and fungal immunity.

Friedrich D, Fecher RA, Rupp J, Deepe GS Jr.

Microbes Infect. 2017 Mar;19(3):204-209. doi: 10.1016/j.micinf.2016.10.008. Epub 2016 Oct 31. Review.

PMID:
27810563
11.

IL-4 Induces Metallothionein 3- and SLC30A4-Dependent Increase in Intracellular Zn(2+) that Promotes Pathogen Persistence in Macrophages.

Subramanian Vignesh K, Landero Figueroa JA, Porollo A, Divanovic S, Caruso JA, Deepe GS Jr.

Cell Rep. 2016 Sep 20;16(12):3232-3246. doi: 10.1016/j.celrep.2016.08.057.

12.

Zinc Induces Dendritic Cell Tolerogenic Phenotype and Skews Regulatory T Cell-Th17 Balance.

George MM, Subramanian Vignesh K, Landero Figueroa JA, Caruso JA, Deepe GS Jr.

J Immunol. 2016 Sep 1;197(5):1864-76. doi: 10.4049/jimmunol.1600410. Epub 2016 Jul 27.

13.

HcZrt2, a zinc responsive gene, is indispensable for the survival of Histoplasma capsulatum in vivo.

Dade J, DuBois JC, Pasula R, Donnell AM, Caruso JA, Smulian AG, Deepe GS Jr.

Med Mycol. 2016 Nov 1;54(8):865-75. doi: 10.1093/mmy/myw045. Epub 2016 Jun 22.

14.

Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis.

Xiong Y, Lingrel JB, Wüthrich M, Klein BS, Vasudevan NT, Jain MK, George M, Deepe GS Jr.

MBio. 2016 Jun 14;7(3). pii: e00436-16. doi: 10.1128/mBio.00436-16.

15.

Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum.

Fecher RA, Horwath MC, Friedrich D, Rupp J, Deepe GS Jr.

J Immunol. 2016 Jul 15;197(2):565-79. doi: 10.4049/jimmunol.1600342. Epub 2016 Jun 6.

16.

Mechanistic studies of the toxicity of zinc gluconate in the olfactory neuronal cell line Odora.

Hsieh H, Vignesh KS, Deepe GS Jr, Choubey D, Shertzer HG, Genter MB.

Toxicol In Vitro. 2016 Sep;35:24-30. doi: 10.1016/j.tiv.2016.05.003. Epub 2016 May 12.

17.

Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity.

Sterkel AK, Lorenzini JL, Fites JS, Subramanian Vignesh K, Sullivan TD, Wuthrich M, Brandhorst T, Hernandez-Santos N, Deepe GS Jr, Klein BS.

Cell Host Microbe. 2016 Mar 9;19(3):361-74. doi: 10.1016/j.chom.2016.02.001. Epub 2016 Feb 25.

18.

Immunological orchestration of zinc homeostasis: The battle between host mechanisms and pathogen defenses.

Subramanian Vignesh K, Deepe GS Jr.

Arch Biochem Biophys. 2016 Dec 1;611:66-78. doi: 10.1016/j.abb.2016.02.020. Epub 2016 Feb 24. Review.

19.

Histoplasma capsulatum, lung infection and immunity.

Horwath MC, Fecher RA, Deepe GS Jr.

Future Microbiol. 2015;10(6):967-75. doi: 10.2217/fmb.15.25. Review.

20.

Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

Wüthrich M, Brandhorst TT, Sullivan TD, Filutowicz H, Sterkel A, Stewart D, Li M, Lerksuthirat T, LeBert V, Shen ZT, Ostroff G, Deepe GS Jr, Hung CY, Cole G, Walter JA, Jenkins MK, Klein B.

Cell Host Microbe. 2015 Apr 8;17(4):452-65. doi: 10.1016/j.chom.2015.02.009. Epub 2015 Mar 19.

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