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Items: 19

1.

Targeting TRAIL.

Ion GND, Nitulescu GM, Popescu CI.

Bioorg Med Chem Lett. 2019 Jul 30. pii: S0960-894X(19)30522-0. doi: 10.1016/j.bmcl.2019.07.053. [Epub ahead of print] Review.

PMID:
31383590
2.

Predictive power of the Triticum root elongation test for the assessment of novel anti‑proliferative therapies.

Olaru OT, Zanfirescu A, Nitulescu GM, Nitulescu G, Dinu-Pirvu CE, Anuta V, Tsatsakis A, Spandidos DA, Margina D, Seremet OC.

Int J Mol Med. 2019 Jul;44(1):16-24. doi: 10.3892/ijmm.2019.4192. Epub 2019 May 10.

3.

In Vitro Anti-proliferative Activity and Mechanism of Action of Anemone nemorosa.

Swanepoel B, Venables L, Olaru OT, Nitulescu GM, van de Venter M.

Int J Mol Sci. 2019 Mar 11;20(5). pii: E1217. doi: 10.3390/ijms20051217.

4.

The Akt pathway in oncology therapy and beyond (Review).

Nitulescu GM, Van De Venter M, Nitulescu G, Ungurianu A, Juzenas P, Peng Q, Olaru OT, Grădinaru D, Tsatsakis A, Tsoukalas D, Spandidos DA, Margina D.

Int J Oncol. 2018 Dec;53(6):2319-2331. doi: 10.3892/ijo.2018.4597. Epub 2018 Oct 16. Review.

5.

Application of molecular framework-based data-mining method in the search for beta-secretase 1 inhibitors through drug repurposing.

Ion GND, Mihai DP, Lupascu G, Nitulescu GM.

J Biomol Struct Dyn. 2019 Sep;37(14):3674-3685. doi: 10.1080/07391102.2018.1526115. Epub 2018 Nov 13.

PMID:
30234434
6.

Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models.

Seremet OC, Olaru OT, Gutu CM, Nitulescu GM, Ilie M, Negres S, Zbarcea CE, Purdel CN, Spandidos DA, Tsatsakis AM, Coleman MD, Margina DM.

Mol Med Rep. 2018 Jun;17(6):7757-7763. doi: 10.3892/mmr.2018.8795. Epub 2018 Mar 26.

7.

Chronic Monosodium Glutamate Administration Induced Hyperalgesia in Mice.

Zanfirescu A, Cristea AN, Nitulescu GM, Velescu BS, Gradinaru D.

Nutrients. 2017 Dec 21;10(1). pii: E1. doi: 10.3390/nu10010001.

8.

Molecular Docking and Screening Studies of New Natural Sortase A Inhibitors.

Nitulescu G, Nicorescu IM, Olaru OT, Ungurianu A, Mihai DP, Zanfirescu A, Nitulescu GM, Margina D.

Int J Mol Sci. 2017 Oct 23;18(10). pii: E2217. doi: 10.3390/ijms18102217.

9.

Structural Analysis of Sortase A Inhibitors.

Nitulescu G, Zanfirescu A, Olaru OT, Nicorescu IM, Nitulescu GM, Margina D.

Molecules. 2016 Nov 22;21(11). pii: E1591.

10.

Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review).

Nitulescu GM, Margina D, Juzenas P, Peng Q, Olaru OT, Saloustros E, Fenga C, Spandidos DΑ, Libra M, Tsatsakis AM.

Int J Oncol. 2016 Mar;48(3):869-85. doi: 10.3892/ijo.2015.3306. Epub 2015 Dec 24. Review.

11.

Anticancer potential of selected Fallopia Adans species.

Olaru OT, Venables L, VAN DE Venter M, Nitulescu GM, Margina D, Spandidos DA, Tsatsakis AM.

Oncol Lett. 2015 Sep;10(3):1323-1332. Epub 2015 Jul 2.

12.

Ethnomedicinal, Phytochemical and Pharmacological Profile of Anthriscus sylvestris as an Alternative Source for Anticancer Lignans.

Olaru OT, Niţulescu GM, Orțan A, Dinu-Pîrvu CE.

Molecules. 2015 Aug 17;20(8):15003-22. doi: 10.3390/molecules200815003. Review.

13.

Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell lines.

Nitulescu GM, Draghici C, Olaru OT, Matei L, Ioana A, Dragu LD, Bleotu C.

Bioorg Med Chem. 2015 Sep 1;23(17):5799-808. doi: 10.1016/j.bmc.2015.07.010. Epub 2015 Jul 11.

PMID:
26193760
14.

Biopharmaceutical profiling of new antitumor pyrazole derivatives.

Anuta V, Nitulescu GM, Dinu-Pîrvu CE, Olaru OT.

Molecules. 2014 Oct 13;19(10):16381-401. doi: 10.3390/molecules191016381.

15.

New potential antitumor pyrazole derivatives: synthesis and cytotoxic evaluation.

Nitulescu GM, Draghici C, Olaru OT.

Int J Mol Sci. 2013 Nov 4;14(11):21805-18. doi: 10.3390/ijms141121805.

16.

In vitro assessment of the antimicrobial activity of new N-acyl-thiourea derivatives.

Diţu LM, Mihăescu G, Chifiriuc C, Bleotu C, Morusciag L, Niţulescu GM, Missir A.

Roum Arch Microbiol Immunol. 2010 Jan-Mar;69(1):41-7.

PMID:
21053783
17.

Synthesis of new pyrazole derivatives and their anticancer evaluation.

Nitulescu GM, Draghici C, Missir AV.

Eur J Med Chem. 2010 Nov;45(11):4914-9. doi: 10.1016/j.ejmech.2010.07.064. Epub 2010 Aug 10.

PMID:
20728965
18.

New thioureides of 2-(4-methylphenoxymethyl) benzoic acid with antimicrobial activity.

Drăcea O, Larion C, Chifiriuc MC, Raut I, Limban C, Niţulescu GM, Bădiceanu CD, Israil AM.

Roum Arch Microbiol Immunol. 2008 Jul-Dec;67(3-4):92-7.

PMID:
19496477
19.

Thioureides of 2-(phenoxymethyl)benzoic acid 4-R substituted: a novel class of anti-parasitic compounds.

Müller J, Limban C, Stadelmann B, Missir AV, Chirita IC, Chifiriuc MC, Nitulescu GM, Hemphill A.

Parasitol Int. 2009 Jun;58(2):128-35. doi: 10.1016/j.parint.2008.12.003. Epub 2008 Dec 25.

PMID:
19162220

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