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Items: 1 to 20 of 75

1.

ZEB2 in T-cells and T-ALL.

De Coninck S, Berx G, Taghon T, Van Vlierberghe P, Goossens S.

Adv Biol Regul. 2019 Jul 27:100639. doi: 10.1016/j.jbior.2019.100639. [Epub ahead of print] Review.

PMID:
31383581
2.

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies.

Pieters T, T'Sas S, Demoen L, Almeida A, Haenebalcke L, Matthijssens F, Lemeire K, D'Hont J, Van Rockeghem F, Hochepied T, Lintermans B, Reunes L, Lammens T, Berx G, Haigh JJ, Goossens S, Van Vlierberghe P.

Sci Rep. 2019 Jul 22;9(1):10577. doi: 10.1038/s41598-019-46853-x.

3.

The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance.

Loret N, Denys H, Tummers P, Berx G.

Cancers (Basel). 2019 Jun 17;11(6). pii: E838. doi: 10.3390/cancers11060838. Review.

4.

A new mouse model to study the role of ectopic Nanos3 expression in cancer.

Andries V, De Keuckelaere E, Staes K, Hochepied T, Taminau J, Lemeire K, Birembaut P, Berx G, van Roy F.

BMC Cancer. 2019 Jun 17;19(1):598. doi: 10.1186/s12885-019-5807-x.

5.

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

Van Hove H, Martens L, Scheyltjens I, De Vlaminck K, Pombo Antunes AR, De Prijck S, Vandamme N, De Schepper S, Van Isterdael G, Scott CL, Aerts J, Berx G, Boeckxstaens GE, Vandenbroucke RE, Vereecke L, Moechars D, Guilliams M, Van Ginderachter JA, Saeys Y, Movahedi K.

Nat Neurosci. 2019 Jun;22(6):1021-1035. doi: 10.1038/s41593-019-0393-4. Epub 2019 May 6.

PMID:
31061494
6.

From neural crest cells to melanocytes: cellular plasticity during development and beyond.

Vandamme N, Berx G.

Cell Mol Life Sci. 2019 May;76(10):1919-1934. doi: 10.1007/s00018-019-03049-w. Epub 2019 Mar 4. Review.

PMID:
30830237
7.

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.

Goossens S, Wang J, Tremblay CS, De Medts J, T'Sas S, Nguyen T, Saw J, Haigh K, Curtis DJ, Van Vlierberghe P, Berx G, Taghon T, Haigh JJ.

Haematologica. 2019 Aug;104(8):1608-1616. doi: 10.3324/haematol.2018.207837. Epub 2019 Jan 24.

8.

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition.

Skrypek N, Bruneel K, Vandewalle C, De Smedt E, Soen B, Loret N, Taminau J, Goossens S, Vandamme N, Berx G.

Epigenetics Chromatin. 2018 Nov 16;11(1):70. doi: 10.1186/s13072-018-0239-4.

9.

An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation.

Haensel D, Sun P, MacLean AL, Ma X, Zhou Y, Stemmler MP, Brabletz S, Berx G, Plikus MV, Nie Q, Brabletz T, Dai X.

EMBO Rep. 2019 Jan;20(1). pii: e46273. doi: 10.15252/embr.201846273. Epub 2018 Nov 9.

PMID:
30413481
10.

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.

Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutierrez-Diaz BT, Wang KK, Johnson MR, Volk AG, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, Abshiru NA, Hijiya N, Peirs S, Vandamme N, Berx G, Goosens S, Marshall SA, Rendleman EJ, Takahashi YH, Wang L, Rawat R, Bartom ET, Collings CK, Van Vlierberghe P, Strikoudis A, Kelly S, Ueberheide B, Mantis C, Kandela I, Bourquin JP, Bornhauser B, Serafin V, Bresolin S, Paganin M, Accordi B, Basso G, Kelleher NL, Weinstock J, Kumar S, Crispino JD, Shilatifard A, Ntziachristos P.

Clin Cancer Res. 2019 Jan 1;25(1):222-239. doi: 10.1158/1078-0432.CCR-18-1740. Epub 2018 Sep 17.

PMID:
30224337
11.

The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.

Scott CL, T'Jonck W, Martens L, Todorov H, Sichien D, Soen B, Bonnardel J, De Prijck S, Vandamme N, Cannoodt R, Saelens W, Vanneste B, Toussaint W, De Bleser P, Takahashi N, Vandenabeele P, Henri S, Pridans C, Hume DA, Lambrecht BN, De Baetselier P, Milling SWF, Van Ginderachter JA, Malissen B, Berx G, Beschin A, Saeys Y, Guilliams M.

Immunity. 2018 Aug 21;49(2):312-325.e5. doi: 10.1016/j.immuni.2018.07.004. Epub 2018 Jul 31.

12.

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia.

Milani G, Matthijssens F, Van Loocke W, Durinck K, Roels J, Peirs S, Thénoz M, Pieters T, Reunes L, Lintermans B, Vandamme N, Lammens T, Van Roy N, Van Nieuwerburgh F, Deforce D, Schwab C, Raimondi S, Dalla Pozza L, Carroll AJ 3rd, De Moerloose B, Benoit Y, Goossens S, Berx G, Harrison CJ, Basso G, Cavé H, Sutton R, Asnafi V, Meijerink J, Mullighan C, Loh M, Van Vlierberghe P.

Br J Haematol. 2019 Apr;185(1):169-174. doi: 10.1111/bjh.15425. Epub 2018 Jun 25. No abstract available.

PMID:
29938777
13.

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

Renard M, Vanhauwaert S, Vanhomwegen M, Rihani A, Vandamme N, Goossens S, Berx G, Van Vlierberghe P, Haigh JJ, Decaesteker B, Van Laere J, Lambertz I, Speleman F, Vandesompele J, Willaert A.

Sci Rep. 2018 May 16;8(1):7642. doi: 10.1038/s41598-018-25389-6.

14.

Nanos genes and their role in development and beyond.

De Keuckelaere E, Hulpiau P, Saeys Y, Berx G, van Roy F.

Cell Mol Life Sci. 2018 Jun;75(11):1929-1946. doi: 10.1007/s00018-018-2766-3. Epub 2018 Feb 3. Review.

PMID:
29397397
15.

Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo.

De Jaeghere E, De Vlieghere E, Van Hoorick J, Van Vlierberghe S, Wagemans G, Pieters L, Melsens E, Praet M, Van Dorpe J, Boone MN, Ghobeira R, De Geyter N, Bracke M, Vanhove C, Neyt S, Berx G, De Geest BG, Dubruel P, Declercq H, Ceelen W, De Wever O.

Biomaterials. 2018 Mar;158:95-105. doi: 10.1016/j.biomaterials.2017.12.017. Epub 2017 Dec 23.

PMID:
29306747
16.

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

Köhler C, Nittner D, Rambow F, Radaelli E, Stanchi F, Vandamme N, Baggiolini A, Sommer L, Berx G, van den Oord JJ, Gerhardt H, Blanpain C, Marine JC.

Cell Stem Cell. 2017 Nov 2;21(5):679-693.e6. doi: 10.1016/j.stem.2017.08.003. Epub 2017 Oct 12.

17.

Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity.

Skrypek N, Goossens S, De Smedt E, Vandamme N, Berx G.

Trends Genet. 2017 Dec;33(12):943-959. doi: 10.1016/j.tig.2017.08.004. Epub 2017 Sep 14. Review.

PMID:
28919019
18.

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

Goossens S, Vandamme N, Van Vlierberghe P, Berx G.

Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):584-591. doi: 10.1016/j.bbcan.2017.06.006. Epub 2017 Jun 29. Review.

PMID:
28669750
19.

Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research.

Vergauwen G, Dhondt B, Van Deun J, De Smedt E, Berx G, Timmerman E, Gevaert K, Miinalainen I, Cocquyt V, Braems G, Van den Broecke R, Denys H, De Wever O, Hendrix A.

Sci Rep. 2017 Jun 2;7(1):2704. doi: 10.1038/s41598-017-02599-y.

20.

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange.

Pieters T, Haenebalcke L, Bruneel K, Vandamme N, Hochepied T, van Hengel J, Wirth D, Berx G, Haigh JJ, van Roy F, Goossens S.

J Vis Exp. 2017 Apr 27;(122). doi: 10.3791/55575.

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