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Items: 1 to 20 of 42


Clinically Relevant Insulin Degludec and its Interaction with Polysaccharides: A Biophysical Examination.

Jiwani SI, Huang S, Beji O, Gyasi-Antwi P, Gillis RB, Adams GG.

Polymers (Basel). 2020 Feb 9;12(2). pii: E390. doi: 10.3390/polym12020390.


The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins.

Dinu V, Lu Y, Weston N, Lithgo R, Coupe H, Channell G, Adams GG, Torcello Gómez A, Sabater C, Mackie A, Parmenter C, Fisk I, Phillips-Jones MK, Harding SE.

Sci Rep. 2020 Jan 22;10(1):960. doi: 10.1038/s41598-020-57776-3.


Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity.

Dinu V, Gillis RB, MacCalman T, Lim M, Adams GG, Harding SE, Fisk ID.

Food Biophys. 2019;14(3):278-286. doi: 10.1007/s11483-019-09574-2. Epub 2019 Apr 15.


Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour.

Dinu V, Yakubov GE, Lim M, Hurst K, Adams GG, Harding SE, Fisk ID.

Int J Biol Macromol. 2019 Oct 1;138:831-836. doi: 10.1016/j.ijbiomac.2019.07.148. Epub 2019 Jul 25.


An enzymatically controlled mucoadhesive system for enhancing flavour during food oral processing.

Dinu V, Gadon A, Hurst K, Lim M, Ayed C, Gillis RB, Adams GG, Harding SE, Fisk ID.

NPJ Sci Food. 2019 Jul 1;3:11. doi: 10.1038/s41538-019-0043-y. eCollection 2019.


Analytical ultracentrifugation in saliva research: Impact of green tea astringency and its significance on the in-vivo aroma release.

Dinu V, Liu C, Ali J, Ayed C, Gershkovich P, Adams GG, Harding SE, Fisk ID.

Sci Rep. 2018 Sep 6;8(1):13350. doi: 10.1038/s41598-018-31625-w.


A simple cell-alignment protocol for sedimentation velocity analytical ultracentrifugation to complement mechanical and optical alignment procedures.

Channell G, Dinu V, Adams GG, Harding SE.

Eur Biophys J. 2018 Oct;47(7):809-813. doi: 10.1007/s00249-018-1328-9. Epub 2018 Aug 29.


Use of the Extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans.

Channell GA, Adams GG, Lu Y, Gillis RB, Dinu V, Grundy MM, Bajka B, Butterworth PJ, Ellis PR, Mackie A, Ballance S, Harding SE.

Sci Rep. 2018 Aug 7;8(1):11809. doi: 10.1038/s41598-018-29997-0.


Characterisation of insulin analogues therapeutically available to patients.

Adams GG, Meal A, Morgan PS, Alzahrani QE, Zobel H, Lithgo R, Kok MS, Besong DTM, Jiwani SI, Ballance S, Harding SE, Chayen N, Gillis RB.

PLoS One. 2018 Mar 29;13(3):e0195010. doi: 10.1371/journal.pone.0195010. eCollection 2018.


Controlled depolymerisation assessed by analytical ultracentrifugation of low molecular weight chitosan for use in archaeological conservation.

Wakefield JMK, Gillis RB, Adams GG, McQueen CMA, Harding SE.

Eur Biophys J. 2018 Oct;47(7):769-775. doi: 10.1007/s00249-018-1290-6. Epub 2018 Mar 17.


Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration.

Phillips-Jones MK, Lithgo R, Dinu V, Gillis RB, Harding JE, Adams GG, Harding SE.

Sci Rep. 2017 Oct 5;7(1):12697. doi: 10.1038/s41598-017-12620-z.


Glargine and degludec: Solution behaviour of higher dose synthetic insulins.

Adams GG, Alzahrani Q, Jiwani SI, Meal A, Morgan PS, Coffey F, Kok S, Rowe AJ, Harding SE, Chayen N, Gillis RB.

Sci Rep. 2017 Aug 4;7(1):7287. doi: 10.1038/s41598-017-06642-w.


The Effectiveness of Lifestyle Adaptation for the Prevention of Prediabetes in Adults: A Systematic Review.

Kerrison G, Gillis RB, Jiwani SI, Alzahrani Q, Kok S, Harding SE, Shaw I, Adams GG.

J Diabetes Res. 2017;2017:8493145. doi: 10.1155/2017/8493145. Epub 2017 Apr 16. Review.


Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin.

Phillips-Jones MK, Channell G, Kelsall CJ, Hughes CS, Ashcroft AE, Patching SG, Dinu V, Gillis RB, Adams GG, Harding SE.

Sci Rep. 2017 Apr 11;7:46180. doi: 10.1038/srep46180.


Both Reversible Self-Association and Structural Changes Underpin Molecular Viscoelasticity of mAb Solutions.

Sarangapani PS, Weaver J, Parupudi A, Besong TMD, Adams GG, Harding SE, Manikwar P, Castellanos MM, Bishop SM, Pathak JA.

J Pharm Sci. 2016 Dec;105(12):3496-3506. doi: 10.1016/j.xphs.2016.08.020. Epub 2016 Oct 25.


Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein.

Abdelhameed AS, Morris GA, Almutairi F, Adams GG, Duvivier P, Conrath K, Harding SE.

Sci Rep. 2016 Oct 26;6:35588. doi: 10.1038/srep35588.


Application of novel analytical ultracentrifuge analysis to solutions of fungal mannans.

Gillis RB, Adams GG, Besong DT, Machová E, Ebringerová A, Rowe AJ, Harding SE, Patel TR.

Eur Biophys J. 2017 Apr;46(3):235-245. doi: 10.1007/s00249-016-1159-5. Epub 2016 Jul 21.


Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils.

Berwick MR, Slope LN, Smith CF, King SM, Newton SL, Gillis RB, Adams GG, Rowe AJ, Harding SE, Britton MM, Peacock AFA.

Chem Sci. 2016 Mar 1;7(3):2207-2216. doi: 10.1039/c5sc04101e. Epub 2015 Dec 22.


A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate.

Abdelhameed AS, Adams GG, Morris GA, Almutairi FM, Duvivier P, Conrath K, Harding SE.

Sci Rep. 2016 Feb 26;6:22208. doi: 10.1038/srep22208.

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