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Items: 1 to 20 of 22


Renal Regenerative Potential of Extracellular Vesicles Derived from miRNA-Engineered Mesenchymal Stromal Cells.

Tapparo M, Bruno S, Collino F, Togliatto G, Deregibus MC, Provero P, Wen S, Quesenberry PJ, Camussi G.

Int J Mol Sci. 2019 May 14;20(10). pii: E2381. doi: 10.3390/ijms20102381.


Rs12778366 single nucleotide polymorphism of Sirtuin 1 (SIRT1) and response to resveratrol supplementation in patients with type 2 diabetes mellitus.

Gambino R, Fanni G, Togliatto G, Ponzo V, Goitre I, Cassader M, Brizzi MF, Bo S.

Acta Diabetol. 2019 Apr 12. doi: 10.1007/s00592-019-01341-6. [Epub ahead of print] No abstract available.


PDGF-BB Carried by Endothelial Cell-Derived Extracellular Vesicles Reduces Vascular Smooth Muscle Cell Apoptosis in Diabetes.

Togliatto G, Dentelli P, Rosso A, Lombardo G, Gili M, Gallo S, Gai C, Solini A, Camussi G, Brizzi MF.

Diabetes. 2018 Apr;67(4):704-716. doi: 10.2337/db17-0371. Epub 2018 Jan 31.


Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury.

Rossetti A, Togliatto G, Rolo AP, Teodoro JS, Granata R, Ghigo E, Columbano A, Palmeira CM, Brizzi MF.

Cell Death Discov. 2017 Dec 4;3:17077. doi: 10.1038/cddiscovery.2017.77. eCollection 2017.


Impact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation.

Bo S, Togliatto G, Gambino R, Ponzo V, Lombardo G, Rosato R, Cassader M, Brizzi MF.

Acta Diabetol. 2018 Apr;55(4):331-340. doi: 10.1007/s00592-017-1097-4. Epub 2018 Jan 12.


Empagliflozin Limits Myocardial Infarction in Vivo and Cell Death in Vitro: Role of STAT3, Mitochondria, and Redox Aspects.

Andreadou I, Efentakis P, Balafas E, Togliatto G, Davos CH, Varela A, Dimitriou CA, Nikolaou PE, Maratou E, Lambadiari V, Ikonomidis I, Kostomitsopoulos N, Brizzi MF, Dimitriadis G, Iliodromitis EK.

Front Physiol. 2017 Dec 19;8:1077. doi: 10.3389/fphys.2017.01077. eCollection 2017.


IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway.

Lombardo G, Gili M, Grange C, Cavallari C, Dentelli P, Togliatto G, Taverna D, Camussi G, Brizzi MF.

Oncogene. 2018 Mar;37(9):1175-1191. doi: 10.1038/s41388-017-0034-x. Epub 2017 Dec 14.


The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side.

Togliatto G, Lombardo G, Brizzi MF.

Int J Mol Sci. 2017 Sep 15;18(9). pii: E1988. doi: 10.3390/ijms18091988. Review.


Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting.

Gallo S, Gili M, Lombardo G, Rossetti A, Rosso A, Dentelli P, Togliatto G, Deregibus MC, Taverna D, Camussi G, Brizzi MF.

PLoS One. 2016 Sep 9;11(9):e0162417. doi: 10.1371/journal.pone.0162417. eCollection 2016.


Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action.

Lombardo G, Dentelli P, Togliatto G, Rosso A, Gili M, Gallo S, Deregibus MC, Camussi G, Brizzi MF.

Sci Rep. 2016 May 9;6:25689. doi: 10.1038/srep25689.


Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications.

Togliatto G, Dentelli P, Brizzi MF.

J Diabetes Res. 2015;2015:373708. doi: 10.1155/2015/373708. Epub 2015 Apr 30. Review.


Unacylated ghrelin induces oxidative stress resistance in a glucose intolerance and peripheral artery disease mouse model by restoring endothelial cell miR-126 expression.

Togliatto G, Trombetta A, Dentelli P, Gallo S, Rosso A, Cotogni P, Granata R, Falcioni R, Delale T, Ghigo E, Brizzi MF.

Diabetes. 2015 Apr;64(4):1370-82. doi: 10.2337/db14-0991. Epub 2014 Nov 3.


miR-221/222 control luminal breast cancer tumor progression by regulating different targets.

Dentelli P, Traversa M, Rosso A, Togliatto G, Olgasi C, Marchiò C, Provero P, Lembo A, Bon G, Annaratone L, Sapino A, Falcioni R, Brizzi MF.

Cell Cycle. 2014;13(11):1811-26. doi: 10.4161/cc.28758. Epub 2014 Apr 15.


Unacylated ghrelin promotes skeletal muscle regeneration following hindlimb ischemia via SOD-2-mediated miR-221/222 expression.

Togliatto G, Trombetta A, Dentelli P, Cotogni P, Rosso A, Tschöp MH, Granata R, Ghigo E, Brizzi MF.

J Am Heart Assoc. 2013 Dec 5;2(6):e000376. doi: 10.1161/JAHA.113.000376.


DNA vaccination against membrane-bound Kit ligand: a new approach to inhibiting tumour growth and angiogenesis.

Olgasi C, Dentelli P, Rosso A, Iavello A, Togliatto G, Toto V, Liberatore M, Barutello G, Musiani P, Cavallo F, Brizzi MF.

Eur J Cancer. 2014 Jan;50(1):234-46. doi: 10.1016/j.ejca.2013.09.016. Epub 2013 Oct 18.


Increase of palmitic acid concentration impairs endothelial progenitor cell and bone marrow-derived progenitor cell bioavailability: role of the STAT5/PPARγ transcriptional complex.

Trombetta A, Togliatto G, Rosso A, Dentelli P, Olgasi C, Cotogni P, Brizzi MF.

Diabetes. 2013 Apr;62(4):1245-57. doi: 10.2337/db12-0646. Epub 2012 Dec 6.


Obestatin regulates adipocyte function and protects against diet-induced insulin resistance and inflammation.

Granata R, Gallo D, Luque RM, Baragli A, Scarlatti F, Grande C, Gesmundo I, Córdoba-Chacón J, Bergandi L, Settanni F, Togliatto G, Volante M, Garetto S, Annunziata M, Chanclón B, Gargantini E, Rocchietto S, Matera L, Datta G, Morino M, Brizzi MF, Ong H, Camussi G, Castaño JP, Papotti M, Ghigo E.

FASEB J. 2012 Aug;26(8):3393-411. doi: 10.1096/fj.11-201343. Epub 2012 May 17.


Des-acyl ghrelin fragments and analogues promote survival of pancreatic β-cells and human pancreatic islets and prevent diabetes in streptozotocin-treated rats.

Granata R, Settanni F, Julien M, Nano R, Togliatto G, Trombetta A, Gallo D, Piemonti L, Brizzi MF, Abribat T, van Der Lely AJ, Ghigo E.

J Med Chem. 2012 Mar 22;55(6):2585-96. doi: 10.1021/jm201223m. Epub 2012 Mar 5.


High glucose via NOX-dependent ROS generation and AKT activity promotes adipose-derived stem cell de-differentiation.

Barale C, Dentelli P, Togliatto G, Trombetta A, Olgasi C, Scozzari G, Toppino M, Morino M, Brizzi MF.

Stem Cells Dev. 2012 Jan 24. doi: 10.1089/scd.2011.0699. Epub 2012 Jan 24. Retraction in: Parker GC. Stem Cells Dev. 2012 Apr 10;21(6):995.


Unacylated ghrelin rescues endothelial progenitor cell function in individuals with type 2 diabetes.

Togliatto G, Trombetta A, Dentelli P, Baragli A, Rosso A, Granata R, Ghigo D, Pegoraro L, Ghigo E, Brizzi MF.

Diabetes. 2010 Apr;59(4):1016-25. doi: 10.2337/db09-0858. Epub 2010 Jan 12.

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