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Items: 1 to 20 of 68

1.

Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis.

Lütjohann D, Stellaard F, Björkhem I.

J Neurol. 2020 Feb;267(2):572-573. doi: 10.1007/s00415-019-09650-0. Epub 2019 Nov 28. No abstract available.

PMID:
31781930
2.

The emerging concept of "individualized cholesterol-lowering therapy": A change in paradigm.

Lütjohann D, Stellaard F, Mulder MT, Sijbrands EJG, Weingärtner O.

Pharmacol Ther. 2019 Jul;199:111-116. doi: 10.1016/j.pharmthera.2019.03.004. Epub 2019 Mar 12. Review.

PMID:
30877023
3.

Cholesterol Absorption and Synthesis in Vegetarians and Omnivores.

Lütjohann D, Meyer S, von Bergmann K, Stellaard F.

Mol Nutr Food Res. 2018 Mar;62(6):e1700689. doi: 10.1002/mnfr.201700689. Epub 2018 Feb 23.

PMID:
29427539
4.

Influence of Chitosan Treatment on Surrogate Serum Markers of Cholesterol Metabolism in Obese Subjects.

Lütjohann D, Marinova M, Wolter K, Willinek W, Bitterlich N, Coenen M, Coch C, Stellaard F.

Nutrients. 2018 Jan 11;10(1). pii: E72. doi: 10.3390/nu10010072.

5.
6.

The value of surrogate markers to monitor cholesterol absorption, synthesis and bioconversion to bile acids under lipid lowering therapies.

Stellaard F, von Bergmann K, Sudhop T, Lütjohann D.

J Steroid Biochem Mol Biol. 2017 May;169:111-122. doi: 10.1016/j.jsbmb.2016.03.030. Epub 2016 Apr 6.

PMID:
27060336
7.

Gastrointestinal pH and Transit Time Profiling in Healthy Volunteers Using the IntelliCap System Confirms Ileo-Colonic Release of ColoPulse Tablets.

Maurer JM, Schellekens RC, van Rieke HM, Wanke C, Iordanov V, Stellaard F, Wutzke KD, Dijkstra G, van der Zee M, Woerdenbag HJ, Frijlink HW, Kosterink JG.

PLoS One. 2015 Jul 15;10(7):e0129076. doi: 10.1371/journal.pone.0129076. eCollection 2015.

8.

Fractional cholesterol absorption measurements in humans: determinants of the blood-based dual stable isotope tracer technique.

Stellaard F, Lütjohann D.

J Clin Lipidol. 2015 Jan-Feb;9(1):14-25. doi: 10.1016/j.jacl.2014.11.002. Epub 2014 Nov 13. Review.

PMID:
25670356
9.

The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.

Demetz E, Schroll A, Auer K, Heim C, Patsch JR, Eller P, Theurl M, Theurl I, Theurl M, Seifert M, Lener D, Stanzl U, Haschka D, Asshoff M, Dichtl S, Nairz M, Huber E, Stadlinger M, Moschen AR, Li X, Pallweber P, Scharnagl H, Stojakovic T, März W, Kleber ME, Garlaschelli K, Uboldi P, Catapano AL, Stellaard F, Rudling M, Kuba K, Imai Y, Arita M, Schuetz JD, Pramstaller PP, Tietge UJF, Trauner M, Norata GD, Claudel T, Hicks AA, Weiss G, Tancevski I.

Cell Metab. 2014 Nov 4;20(5):787-798. doi: 10.1016/j.cmet.2014.09.004.

10.

Isotope-labelled urea to test colon drug delivery devices in vivo: principles, calculations and interpretations.

Maurer MJ, Schellekens RC, Wutzke KD, Stellaard F.

Isotopes Environ Health Stud. 2013;49(4):473-91. doi: 10.1080/10256016.2013.803099. Review.

PMID:
24313370
11.

Laxative treatment with polyethylene glycol decreases microbial primary bile salt dehydroxylation and lipid metabolism in the intestine of rats.

van der Wulp MY, Derrien M, Stellaard F, Wolters H, Kleerebezem M, Dekker J, Rings EH, Groen AK, Verkade HJ.

Am J Physiol Gastrointest Liver Physiol. 2013 Oct 1;305(7):G474-82. doi: 10.1152/ajpgi.00375.2012. Epub 2013 Jul 18.

12.

Reduced absorption of long-chain fatty acids during methotrexate-induced gastrointestinal mucositis in the rat.

Fijlstra M, Tissing WJ, Stellaard F, Verkade HJ, Rings EH.

Clin Nutr. 2013 Jun;32(3):452-9. doi: 10.1016/j.clnu.2012.10.002. Epub 2012 Oct 5.

PMID:
23102689
13.

Laxative treatment with polyethylene glycol does not affect lipid absorption in rats.

van der Wulp MY, Cuperus FJ, Stellaard F, van Dijk TH, Dekker J, Rings EH, Groen AK, Verkade HJ.

J Pediatr Gastroenterol Nutr. 2012 Oct;55(4):457-62.

PMID:
23013930
14.

A non-invasive, low-cost study design to determine the release profile of colon drug delivery systems: a feasibility study.

Maurer MJ, Schellekens RC, Wutzke KD, Dijkstra G, Woerdenbag HJ, Frijlink HW, Kosterink JG, Stellaard F.

Pharm Res. 2012 Aug;29(8):2070-8. doi: 10.1007/s11095-012-0735-3. Epub 2012 Mar 16.

PMID:
22422322
15.

Applications of stable isotopes in clinical pharmacology.

Schellekens RC, Stellaard F, Woerdenbag HJ, Frijlink HW, Kosterink JG.

Br J Clin Pharmacol. 2011 Dec;72(6):879-97. doi: 10.1111/j.1365-2125.2011.04071.x. Review. Erratum in: Br J Clin Pharmacol. 2013 Apr;75(4):1171.

16.

Unconjugated bile salts shuttle through hepatocyte peroxisomes for taurine conjugation.

Rembacz KP, Woudenberg J, Hoekstra M, Jonkers EZ, van den Heuvel FA, Buist-Homan M, Woudenberg-Vrenken TE, Rohacova J, Marin ML, Miranda MA, Moshage H, Stellaard F, Faber KN.

Hepatology. 2010 Dec;52(6):2167-76. doi: 10.1002/hep.23954. Epub 2010 Nov 3.

PMID:
21049545
17.

Film coated tablets (ColoPulse technology) for targeted delivery in the lower intestinal tract: influence of the core composition on release characteristics.

Schellekens RC, Baltink JH, Woesthuis EM, Stellaard F, Kosterink JG, Woerdenbag HJ, Frijlink HW.

Pharm Dev Technol. 2012 Jan-Feb;17(1):40-7. doi: 10.3109/10837450.2010.513986. Epub 2010 Oct 5.

PMID:
20923321
18.

Plasma bile acids are not associated with energy metabolism in humans.

Brufau G, Bahr MJ, Staels B, Claudel T, Ockenga J, Böker KH, Murphy EJ, Prado K, Stellaard F, Manns MP, Kuipers F, Tietge UJ.

Nutr Metab (Lond). 2010 Sep 3;7:73. doi: 10.1186/1743-7075-7-73.

19.

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism.

Brufau G, Stellaard F, Prado K, Bloks VW, Jonkers E, Boverhof R, Kuipers F, Murphy EJ.

Hepatology. 2010 Oct;52(4):1455-64. doi: 10.1002/hep.23831.

PMID:
20725912
20.

Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice.

Jakulj L, Vissers MN, van Roomen CP, van der Veen JN, Vrins CL, Kunne C, Stellaard F, Kastelein JJ, Groen AK.

FEBS Lett. 2010 Aug 20;584(16):3625-8. doi: 10.1016/j.febslet.2010.07.035. Epub 2010 Jul 24.

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