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Items: 1 to 20 of 21


Synthetic lethality: a step forward for personalized medicine in cancer.

Jariyal H, Weinberg F, Achreja A, Nagarath D, Srivastava A.

Drug Discov Today. 2019 Dec 4. pii: S1359-6446(19)30456-8. doi: 10.1016/j.drudis.2019.11.014. [Epub ahead of print] Review.


Reactive Oxygen Species in the Tumor Microenvironment: An Overview.

Weinberg F, Ramnath N, Nagrath D.

Cancers (Basel). 2019 Aug 16;11(8). pii: E1191. doi: 10.3390/cancers11081191. Review.


Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.

Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A.

Cell Metab. 2019 Aug 6;30(2):385-401.e9. doi: 10.1016/j.cmet.2019.06.017.


Combination pembrolizumab plus chemotherapy: a new standard of care for patients with advanced non-small-cell lung cancer.

Weinberg F, Gadgeel S.

Lung Cancer (Auckl). 2019 Jun 4;10:47-56. doi: 10.2147/LCTT.S176391. eCollection 2019.


Targeting IL22: a potential therapeutic approach for Kras mutant lung cancer?

Weinberg FD, Ramnath N.

Transl Lung Cancer Res. 2018 Sep;7(Suppl 3):S243-S247. doi: 10.21037/tlcr.2018.09.04. No abstract available.


Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function.

Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM.

Cancer Res. 2014 Sep 15;74(18):5118-26. doi: 10.1158/0008-5472.CAN-14-0660. Epub 2014 Jul 21.


Algebraic and combinatorial properties of common RNA pseudoknot classes with applications.

Nebel ME, Weinberg F.

J Comput Biol. 2012 Oct;19(10):1134-50. doi: 10.1089/cmb.2011.0094.


Random generation of RNA secondary structures according to native distributions.

Nebel ME, Scheid A, Weinberg F.

Algorithms Mol Biol. 2011 Oct 12;6:24. doi: 10.1186/1748-7188-6-24.


Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Weinberg F, Hamanaka R, Wheaton WW, Weinberg S, Joseph J, Lopez M, Kalyanaraman B, Mutlu GM, Budinger GR, Chandel NS.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26.


Mitochondrial metabolism and cancer.

Weinberg F, Chandel NS.

Ann N Y Acad Sci. 2009 Oct;1177:66-73. doi: 10.1111/j.1749-6632.2009.05039.x. Review.


Reactive oxygen species-dependent signaling regulates cancer.

Weinberg F, Chandel NS.

Cell Mol Life Sci. 2009 Dec;66(23):3663-73. doi: 10.1007/s00018-009-0099-y. Epub 2009 Jul 24. Review.


Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio.

Emerling BM, Weinberg F, Snyder C, Burgess Z, Mutlu GM, Viollet B, Budinger GR, Chandel NS.

Free Radic Biol Med. 2009 May 15;46(10):1386-91. doi: 10.1016/j.freeradbiomed.2009.02.019. Epub 2009 Mar 3.


Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS.

Klimova TA, Bell EL, Shroff EH, Weinberg FD, Snyder CM, Dimri GP, Schumacker PT, Budinger GR, Chandel NS.

FASEB J. 2009 Mar;23(3):783-94. doi: 10.1096/fj.08-114256. Epub 2008 Oct 23.


Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.

Meoli E, Bossis I, Cazabat L, Mavrakis M, Horvath A, Stergiopoulos S, Shiferaw ML, Fumey G, Perlemoine K, Muchow M, Robinson-White A, Weinberg F, Nesterova M, Patronas Y, Groussin L, Bertherat J, Stratakis CA.

Cancer Res. 2008 May 1;68(9):3133-41. doi: 10.1158/0008-5472.CAN-08-0064.


PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).

Emerling BM, Weinberg F, Liu JL, Mak TW, Chandel NS.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2622-7. doi: 10.1073/pnas.0706790105. Epub 2008 Feb 11.


Large deletions of the PRKAR1A gene in Carney complex.

Horvath A, Bossis I, Giatzakis C, Levine E, Weinberg F, Meoli E, Robinson-White A, Siegel J, Soni P, Groussin L, Matyakhina L, Verma S, Remmers E, Nesterova M, Carney JA, Bertherat J, Stratakis CA.

Clin Cancer Res. 2008 Jan 15;14(2):388-95. doi: 10.1158/1078-0432.CCR-07-1155.


A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation.

Lin X, David CA, Donnelly JB, Michaelides M, Chandel NS, Huang X, Warrior U, Weinberg F, Tormos KV, Fesik SW, Shen Y.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):174-9. doi: 10.1073/pnas.0706585104. Epub 2008 Jan 2.


Enzastaurin (LY317615), a protein kinase Cbeta inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines.

Rizvi MA, Ghias K, Davies KM, Ma C, Weinberg F, Munshi HG, Krett NL, Rosen ST.

Mol Cancer Ther. 2006 Jul;5(7):1783-9.


Insulin augments GnRH-stimulated LHbeta gene expression by Egr-1.

Buggs C, Weinberg F, Kim E, Wolfe A, Radovick S, Wondisford F.

Mol Cell Endocrinol. 2006 Apr 25;249(1-2):99-106. Epub 2006 Mar 10.


A mouse model for Carney complex.

Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos S, Robinson-White A, Weinberg F, Meoli E, Bornstein SR, Stratakis CA.

Endocr Res. 2004 Nov;30(4):903-11.


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