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Items: 1 to 20 of 41


Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.

Aitken L, Benek O, McKelvie BE, Hughes RE, Hroch L, Schmidt M, Major LL, Vinklarova L, Kuca K, Smith TK, Musilek K, Gunn-Moore FJ.

Molecules. 2019 Jul 29;24(15). pii: E2757. doi: 10.3390/molecules24152757.


Approaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis.

Abdul Razzak R, Florence GJ, Gunn-Moore FJ.

Int J Mol Sci. 2019 Jun 25;20(12). pii: E3108. doi: 10.3390/ijms20123108. Review.


All-Optical Assay to Study Biological Neural Networks.

Afshar Saber W, Gasparoli FM, Dirks MG, Gunn-Moore FJ, Antkowiak M.

Front Neurosci. 2018 Jul 5;12:451. doi: 10.3389/fnins.2018.00451. eCollection 2018.


Light-sheet microscopy with attenuation-compensated propagation-invariant beams.

Nylk J, McCluskey K, Preciado MA, Mazilu M, Yang Z, Gunn-Moore FJ, Aggarwal S, Tello JA, Ferrier DEK, Dholakia K.

Sci Adv. 2018 Apr 6;4(4):eaar4817. doi: 10.1126/sciadv.aar4817. eCollection 2018 Apr.


In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease.

Aitken L, Baillie G, Pannifer A, Morrison A, Jones PS, Smith TK, McElroy SP, Gunn-Moore FJ.

SLAS Discov. 2017 Jul;22(6):676-685. doi: 10.1177/2472555217697964. Epub 2017 Mar 17.


Willing to Be Involved in Cancer.

Gunn-Moore FJ, Tilston-Lünel AM, Reynolds PA.

Genes (Basel). 2016 Jul 18;7(7). pii: E37. doi: 10.3390/genes7070037. Review.


Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells.

Tilston-Lünel AM, Haley KE, Schlecht NF, Wang Y, Chatterton AL, Moleirinho S, Watson A, Hundal HS, Prystowsky MB, Gunn-Moore FJ, Reynolds PA.

J Mol Cell Biol. 2016 Apr 18. [Epub ahead of print]


Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10.

Aitken L, Quinn SD, Perez-Gonzalez C, Samuel ID, Penedo JC, Gunn-Moore FJ.

Chembiochem. 2016 Jun 2;17(11):1029-37. doi: 10.1002/cbic.201600081. Epub 2016 Apr 25.


Visualization of podocyte substructure with structured illumination microscopy (SIM): a new approach to nephrotic disease.

Pullman JM, Nylk J, Campbell EC, Gunn-Moore FJ, Prystowsky MB, Dholakia K.

Biomed Opt Express. 2016 Jan 6;7(2):302-11. doi: 10.1364/BOE.7.000302. eCollection 2016 Feb 1.


Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF).

Kailainathan S, Piers TM, Yi JH, Choi S, Fahey MS, Borger E, Gunn-Moore FJ, O'Neill L, Lever M, Whitcomb DJ, Cho K, Allen SJ.

Pharmacol Res. 2016 Feb;104:97-107. doi: 10.1016/j.phrs.2015.12.008. Epub 2015 Dec 11.


Fibroblasts in Head and Neck Squamous Cell Carcinoma Associated With Perineural Invasion Have High-Level Nuclear Yes-Associated Protein (YAP) Expression.

Wang Y, Gersten A, Moleirinho S, Gunn-Moore FJ, Reynolds PA, Prystowsky MB.

Acad Pathol. 2015 Nov 26;2(4):2374289515616972. doi: 10.1177/2374289515616972. eCollection 2015 Oct-Dec.


Macro-optical trapping for sample confinement in light sheet microscopy.

Yang Z, Piksarv P, Ferrier DE, Gunn-Moore FJ, Dholakia K.

Biomed Opt Express. 2015 Jul 8;6(8):2778-85. doi: 10.1364/BOE.6.002778. eCollection 2015 Aug 1.


A compact Airy beam light sheet microscope with a tilted cylindrical lens.

Yang Z, Prokopas M, Nylk J, Coll-Lladó C, Gunn-Moore FJ, Ferrier DE, Vettenburg T, Dholakia K.

Biomed Opt Express. 2014 Sep 5;5(10):3434-42. doi: 10.1364/BOE.5.003434. eCollection 2014 Oct 1.


Light-sheet microscopy using an Airy beam.

Vettenburg T, Dalgarno HI, Nylk J, Coll-Lladó C, Ferrier DE, Čižmár T, Gunn-Moore FJ, Dholakia K.

Nat Methods. 2014 May;11(5):541-4. doi: 10.1038/nmeth.2922. Epub 2014 Apr 6.


Fast targeted gene transfection and optogenetic modification of single neurons using femtosecond laser irradiation.

Antkowiak M, Torres-Mapa ML, Witts EC, Miles GB, Dholakia K, Gunn-Moore FJ.

Sci Rep. 2013 Nov 21;3:3281. doi: 10.1038/srep03281.


Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform.

Mitchell CA, Kalies S, Cizmár T, Heisterkamp A, Torrance L, Roberts AG, Gunn-Moore FJ, Dholakia K.

PLoS One. 2013 Nov 14;8(11):e79235. doi: 10.1371/journal.pone.0079235. eCollection 2013.


Femtosecond optical transfection of individual mammalian cells.

Antkowiak M, Torres-Mapa ML, Stevenson DJ, Dholakia K, Gunn-Moore FJ.

Nat Protoc. 2013 Jun;8(6):1216-33. doi: 10.1038/nprot.2013.071. Epub 2013 May 30.


Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts.

Moleirinho S, Patrick C, Tilston-Lünel AM, Higginson JR, Angus L, Antkowiak M, Barnett SC, Prystowsky MB, Reynolds PA, Gunn-Moore FJ.

PLoS One. 2013 Apr 8;8(4):e60028. doi: 10.1371/journal.pone.0060028. Print 2013.


High-throughput optical injection of mammalian cells using a Bessel light beam.

Rendall HA, Marchington RF, Praveen BB, Bergmann G, Arita Y, Heisterkamp A, Gunn-Moore FJ, Dholakia K.

Lab Chip. 2012 Nov 21;12(22):4816-20. doi: 10.1039/c2lc40708f.


Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β.

Doherty GH, Beccano-Kelly D, Yan SD, Gunn-Moore FJ, Harvey J.

Neurobiol Aging. 2013 Jan;34(1):226-37. doi: 10.1016/j.neurobiolaging.2012.08.003. Epub 2012 Aug 22.


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