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Lipid Related Genes Altered in NASH Connect Inflammation in Liver Pathogenesis Progression to HCC: A Canonical Pathway.

Desterke C, Chiappini F.

Int J Mol Sci. 2019 Nov 8;20(22). pii: E5594. doi: 10.3390/ijms20225594.


Randomized controlled trial demonstrates the benefit of RGTA® based matrix therapy to treat tendinopathies in racing horses.

Jacquet-Guibon S, Dupays AG, Coudry V, Crevier-Denoix N, Leroy S, Siñeriz F, Chiappini F, Barritault D, Denoix JM.

PLoS One. 2018 Mar 9;13(3):e0191796. doi: 10.1371/journal.pone.0191796. eCollection 2018.


Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis.

Darnaud M, Dos Santos A, Gonzalez P, Augui S, Lacoste C, Desterke C, De Hertogh G, Valentino E, Braun E, Zheng J, Boisgard R, Neut C, Dubuquoy L, Chiappini F, Samuel D, Lepage P, Guerrieri F, Doré J, Bréchot C, Moniaux N, Faivre J.

Gastroenterology. 2018 Mar;154(4):1009-1023.e14. doi: 10.1053/j.gastro.2017.11.003. Epub 2017 Nov 11.


Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients.

Chiappini F, Coilly A, Kadar H, Gual P, Tran A, Desterke C, Samuel D, Duclos-Vallée JC, Touboul D, Bertrand-Michel J, Brunelle A, Guettier C, Le Naour F.

Sci Rep. 2017 Apr 24;7:46658. doi: 10.1038/srep46658.


Hepatic and serum lipid signatures specific to nonalcoholic steatohepatitis in murine models.

Chiappini F, Desterke C, Bertrand-Michel J, Guettier C, Le Naour F.

Sci Rep. 2016 Aug 11;6:31587. doi: 10.1038/srep31587.


Discrimination of cirrhotic nodules, dysplastic lesions and hepatocellular carcinoma by their vibrational signature.

Peng C, Kaščáková S, Chiappini F, Olaya N, Sandt C, Yousef I, Samuel D, Dumas P, Guettier C, Le Naour F.

J Transl Med. 2016 Jan 12;14:9. doi: 10.1186/s12967-016-0763-6.


Vibrational signatures to discriminate liver steatosis grades.

Peng C, Chiappini F, Kaščáková S, Danulot M, Sandt C, Samuel D, Dumas P, Guettier C, Le Naour F.

Analyst. 2015 Feb 21;140(4):1107-18. doi: 10.1039/c4an01679c.


Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice.

Chiappini F, Catalano KJ, Lee J, Peroni OD, Lynch J, Dhaneshwar AS, Wellenstein K, Sontheimer A, Neel BG, Kahn BB.

J Clin Invest. 2014 Sep;124(9):3781-92. doi: 10.1172/JCI68585. Epub 2014 Aug 1.


Single vs. two-photon microscopy for label free intrinsic tissue studies in the UV light region.

Zubkovs V, Jamme F, Kascakova S, Chiappini F, Le Naour F, Réfrégiers M.

Analyst. 2014 Jun 7;139(11):2663-7. doi: 10.1039/c4an00203b.


In situ chemical composition analysis of cirrhosis by combining synchrotron fourier transform infrared and synchrotron X-ray fluorescence microspectroscopies on the same tissue section.

Le Naour F, Sandt C, Peng C, Trcera N, Chiappini F, Flank AM, Guettier C, Dumas P.

Anal Chem. 2012 Dec 4;84(23):10260-6. doi: 10.1021/ac302072t. Epub 2012 Nov 13.


Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.

Chiappini F, Ramadoss P, Vella KR, Cunha LL, Ye FD, Stuart RC, Nillni EA, Hollenberg AN.

Mol Cell Endocrinol. 2013 Jan 5;365(1):84-94. doi: 10.1016/j.mce.2012.09.006. Epub 2012 Sep 20.


Circulating tumor cells measurements in hepatocellular carcinoma.

Chiappini F.

Int J Hepatol. 2012;2012:684802. doi: 10.1155/2012/684802. Epub 2012 May 28.


Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.

Chiappini F, Cunha LL, Harris JC, Hollenberg AN.

J Biol Chem. 2011 Mar 11;286(10):8094-105. doi: 10.1074/jbc.M110.178186. Epub 2011 Jan 5.


Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level.

Perello M, Cakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA.

Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E976-89. doi: 10.1152/ajpendo.00448.2010. Epub 2010 Sep 21. Erratum in: Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E422.


Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alpha.

Ramadoss P, Chiappini F, Bilban M, Hollenberg AN.

J Biol Chem. 2010 May 28;285(22):16453-66. doi: 10.1074/jbc.M109.066936. Epub 2010 Mar 19.


Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study.

Chiappini F, Teicher E, Saffroy R, Debuire B, Vittecoq D, Lemoine A.

Curr HIV Res. 2009 Mar;7(2):244-53.


Generation and modulation of hepatocellular carcinoma circulating cells: a new experimental model.

Scatton O, Chiappini F, Liu XH, Riou P, Marconi A, Debuire B, Azoulay D, Lemoine A.

J Surg Res. 2008 Dec;150(2):183-9. doi: 10.1016/j.jss.2008.03.052. Epub 2008 Apr 28.


Exploration of global gene expression in human liver steatosis by high-density oligonucleotide microarray.

Chiappini F, Barrier A, Saffroy R, Domart MC, Dagues N, Azoulay D, Sebagh M, Franc B, Chevalier S, Debuire B, Dudoit S, Lemoine A.

Lab Invest. 2006 Feb;86(2):154-65.


Gene expression profiling of nonneoplastic mucosa may predict clinical outcome of colon cancer patients.

Barrier A, Boelle PY, Lemoine A, Tse C, Brault D, Chiappini F, Lacaine F, Houry S, Huguier M, Flahault A, Dudoit S.

Dis Colon Rectum. 2005 Dec;48(12):2238-48.


Ischemic preconditioning modulates the expression of several genes, leading to the overproduction of IL-1Ra, iNOS, and Bcl-2 in a human model of liver ischemia-reperfusion.

Barrier A, Olaya N, Chiappini F, Roser F, Scatton O, Artus C, Franc B, Dudoit S, Flahault A, Debuire B, Azoulay D, Lemoine A.

FASEB J. 2005 Oct;19(12):1617-26.


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