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Int J Artif Organs. 2017 Nov 24;40(12):683-689. doi: 10.5301/ijao.5000634. Epub 2017 Aug 11.

An original valveless artificial heart providing pulsatile flow tested in mock circulatory loops.

Author information

1
 Cardiovascular Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne - Switzerland.
2
 Laboratory for Hydraulic Machines, EPFL, Ecole Polytechnique Fédérale Lausanne, Lausanne - Switzerland.
3
 Lausanne University School of Medicine, Lausanne - Switzerland.

Abstract

PURPOSE:

We present the test bench results of a valveless total artificial heart that is potentially compatible with the pediatric population.

METHODS:

The RollingHeart is a valveless volumetric pump generating pulsatile flow. It consists of a single spherical cavity divided into 4 chambers by 2 rotating disks. The combined rotations of both disks produce changes in the volumes of the 4 cavities (suction and ejection). The blood enters/exits the spherical cavity through 4 openings that are symmetrical to the fixed rotation axis of the first disk.Mock circulatory system: The device pumps a 37% glycerin solution through 2 parallel circuits, simulating the pulmonary and systemic circulations. Flow rates are acquired with a magnetic inductive flowmeter, while pressure sensors collect pressure in the left and right outflow and inflow tracts.In vitro test protocol: The pump is run at speeds ranging from 20 to 180 ejections per minute. The waveform of the pressure generated at the inflow and outflow of the 4 chambers and the flow rate in the systemic circulation are measured.

RESULTS:

At an ejection rate of 178 min-1, the RollingHeart pumps 5.3 L/min for a systemic maximal pressure gradient of 174 mmHg and a pulmonary maximal pressure gradient of 75 mmHg. The power input was 14 W, corresponding to an efficiency of 21%.

CONCLUSIONS:

The RollingHeart represents a new approach in the domain of total artificial heart. This preliminary study endorses the feasibility of a single valveless device acting as a total artificial heart.

PMID:
28862717
DOI:
10.5301/ijao.5000634
[Indexed for MEDLINE]

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