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Items: 1 to 20 of 30


Behavioral Analyses of Animal Models of Intellectual and Developmental Disabilities.

Crawley JN, Fagiolini M, Harrison FE, Samaco R, Wozniak DF, Robinson MB.

Neurobiol Learn Mem. 2019 Sep 6:107087. doi: 10.1016/j.nlm.2019.107087. [Epub ahead of print]


Cell-free hemoglobin augments acute kidney injury during experimental sepsis.

Shaver CM, Paul MG, Putz ND, Landstreet SR, Kuck JL, Scarfe L, Skrypnyk NI, Yang H, Harrison FE, de Caestecker MP, Bastarache JA, Ware LB.

Am J Physiol Renal Physiol. 2019 Jul 31. doi: 10.1152/ajprenal.00375.2018. [Epub ahead of print]


Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.

DiCarlo GE, Aguilar JI, Matthies HJ, Harrison FE, Bundschuh KE, West A, Hashemi P, Herborg F, Rickhag M, Chen H, Gether U, Wallace MT, Galli A.

J Clin Invest. 2019 May 16;129(8):3407-3419. doi: 10.1172/JCI127411.


Impaired amygdala-based learning and decreased anxiety in a murine model of pseudohypoparathyroidism type 1A.

Shoemaker AH, Paffenroth KC, Bingham N, Harrison FE.

Behav Brain Res. 2019 Jul 23;367:53-58. doi: 10.1016/j.bbr.2019.03.041. Epub 2019 Mar 25.


Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma.

Bernardo-Colón A, Vest V, Clark A, Cooper ML, Calkins DJ, Harrison FE, Rex TS.

Cell Death Dis. 2018 Oct 26;9(11):1097. doi: 10.1038/s41419-018-1061-4.


Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice.

Mi DJ, Dixit S, Warner TA, Kennard JA, Scharf DA, Kessler ES, Moore LM, Consoli DC, Bown CW, Eugene AJ, Kang JQ, Harrison FE.

Neurobiol Aging. 2018 Nov;71:241-254. doi: 10.1016/j.neurobiolaging.2018.08.002. Epub 2018 Aug 7.


Oxidative Stress Levels in the Brain Are Determined by Post-Mortem Interval and Ante-Mortem Vitamin C State but Not Alzheimer's Disease Status.

Eckman J, Dixit S, Nackenoff A, Schrag M, Harrison FE.

Nutrients. 2018 Jul 9;10(7). pii: E883. doi: 10.3390/nu10070883.


Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens.

Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M.

Free Radic Biol Med. 2018 Feb 1;115:351-360. doi: 10.1016/j.freeradbiomed.2017.12.016. Epub 2017 Dec 15.


Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate.

Dixit S, Fessel JP, Harrison FE.

Free Radic Biol Med. 2017 Nov;112:515-523. doi: 10.1016/j.freeradbiomed.2017.08.021. Epub 2017 Aug 31.


Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease.

Walker JM, Dixit S, Saulsberry AC, May JM, Harrison FE.

Neurobiol Dis. 2017 Apr;100:87-98. doi: 10.1016/j.nbd.2017.01.004. Epub 2017 Jan 17.


Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive Decline.

Walker JM, Harrison FE.

Nutrients. 2015 Sep 1;7(9):7332-57. doi: 10.3390/nu7095341. Review.


Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics.

Rao SK, Ross JM, Harrison FE, Bernardo A, Reiserer RS, Reiserer RS, Mobley JA, McDonald MP.

Neurobiol Dis. 2015 Jun;78:45-55. doi: 10.1016/j.nbd.2015.03.018. Epub 2015 Mar 25.


Low brain ascorbic acid increases susceptibility to seizures in mouse models of decreased brain ascorbic acid transport and Alzheimer's disease.

Warner TA, Kang JQ, Kennard JA, Harrison FE.

Epilepsy Res. 2015 Feb;110:20-5. doi: 10.1016/j.eplepsyres.2014.11.017. Epub 2014 Nov 26.


Vitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control manner.

He XB, Kim M, Kim SY, Yi SH, Rhee YH, Kim T, Lee EH, Park CH, Dixit S, Harrison FE, Lee SH.

Stem Cells. 2015 Apr;33(4):1320-32. doi: 10.1002/stem.1932.


Ascorbic acid and the brain: rationale for the use against cognitive decline.

Harrison FE, Bowman GL, Polidori MC.

Nutrients. 2014 Apr 24;6(4):1752-81. doi: 10.3390/nu6041752. Review.


Intravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice.

Kennard JA, Harrison FE.

Behav Brain Res. 2014 May 1;264:34-42. doi: 10.1016/j.bbr.2014.01.044. Epub 2014 Feb 5.


Antioxidant supplementation ameliorates molecular deficits in Smith-Lemli-Opitz syndrome.

Korade Z, Xu L, Harrison FE, Ahsen R, Hart SE, Folkes OM, Mirnics K, Porter NA.

Biol Psychiatry. 2014 Feb 1;75(3):215-22. doi: 10.1016/j.biopsych.2013.06.013. Epub 2013 Jul 26.


Role of vitamin C in the function of the vascular endothelium.

May JM, Harrison FE.

Antioxid Redox Signal. 2013 Dec 10;19(17):2068-83. doi: 10.1089/ars.2013.5205. Epub 2013 May 29. Review.


Combined vitamin C and E deficiency induces motor defects in gulo(-/-)/SVCT2(+/-) mice.

Pierce MR, Diasio DL, Rodrigues LM, Harrison FE, May JM.

Nutr Neurosci. 2013 Jul;16(4):160-73. doi: 10.1179/1476830512Y.0000000042. Epub 2012 Dec 4. Erratum in: Nutr Neurosci. 2013 Sep;16(5):240-2.


Behavioral and monoamine changes following severe vitamin C deficiency.

Ward MS, Lamb J, May JM, Harrison FE.

J Neurochem. 2013 Feb;124(3):363-75. doi: 10.1111/jnc.12069. Epub 2012 Nov 30.

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