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Items: 1 to 20 of 25

1.

Comparisons of In Vivo and In Vitro Opioid Effects of Newly Synthesized 14-Methoxycodeine-6-O-sulfate and Codeine-6-O-sulfate.

Zádor F, Mohammadzadeh A, Balogh M, Zádori ZS, Király K, Barsi S, Galambos AR, László SB, Hutka B, Váradi A, Hosztafi S, Riba P, Benyhe S, Fürst S, Al-Khrasani M.

Molecules. 2020 Mar 17;25(6). pii: E1370. doi: 10.3390/molecules25061370.

2.

Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists.

Szűcs E, Stefanucci A, Dimmito MP, Zádor F, Pieretti S, Zengin G, Vécsei L, Benyhe S, Nalli M, Mollica A.

Biomolecules. 2020 Feb 12;10(2). pii: E284. doi: 10.3390/biom10020284.

3.

Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening.

Poli G, Dimmito MP, Mollica A, Zengin G, Benyhe S, Zador F, Stefanucci A.

Molecules. 2019 Oct 27;24(21). pii: E3872. doi: 10.3390/molecules24213872.

4.

Kynurenines and the Endocannabinoid System in Schizophrenia: Common Points and Potential Interactions.

Zádor F, Nagy-Grócz G, Kekesi G, Dvorácskó S, Szűcs E, Tömböly C, Horvath G, Benyhe S, Vécsei L.

Molecules. 2019 Oct 15;24(20). pii: E3709. doi: 10.3390/molecules24203709. Review.

5.

Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine.

Kudla L, Bugno R, Skupio U, Wiktorowska L, Solecki W, Wojtas A, Golembiowska K, Zádor F, Benyhe S, Buda S, Makuch W, Przewlocka B, Bojarski AJ, Przewlocki R.

Br J Pharmacol. 2019 Dec;176(23):4434-4445. doi: 10.1111/bph.14805. Epub 2019 Dec 8.

PMID:
31347704
6.

Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors.

Dvorácskó S, Keresztes A, Mollica A, Stefanucci A, Macedonio G, Pieretti S, Zádor F, Walter FR, Deli MA, Kékesi G, Bánki L, Tuboly G, Horváth G, Tömböly C.

Eur J Med Chem. 2019 Sep 15;178:571-588. doi: 10.1016/j.ejmech.2019.05.037. Epub 2019 May 21.

PMID:
31220675
7.

Efficacy-Based Perspective to Overcome Reduced Opioid Analgesia of Advanced Painful Diabetic Neuropathy in Rats.

Balogh M, Zádor F, Zádori ZS, Shaqura M, Király K, Mohammadzadeh A, Varga B, Lázár B, Mousa SA, Hosztafi S, Riba P, Benyhe S, Gyires K, Schäfer M, Fürst S, Al-Khrasani M.

Front Pharmacol. 2019 Apr 9;10:347. doi: 10.3389/fphar.2019.00347. eCollection 2019.

8.

The Peripheral Versus Central Antinociception of a Novel Opioid Agonist: Acute Inflammatory Pain in Rats.

Balogh M, Zádori ZS, Lázár B, Karádi D, László S, Mousa SA, Hosztafi S, Zádor F, Riba P, Schäfer M, Fürst S, Al-Khrasani M.

Neurochem Res. 2018 Jun;43(6):1250-1257. doi: 10.1007/s11064-018-2542-7. Epub 2018 May 3.

PMID:
29725918
9.

Biochemical and pharmacological characterization of three opioid-nociceptin hybrid peptide ligands reveals substantially differing modes of their actions.

Erdei AI, Borbély A, Magyar A, Taricska N, Perczel A, Zsíros O, Garab G, Szűcs E, Ötvös F, Zádor F, Balogh M, Al-Khrasani M, Benyhe S.

Peptides. 2018 Jan;99:205-216. doi: 10.1016/j.peptides.2017.10.005. Epub 2017 Oct 13.

PMID:
29038035
10.

14-O-Methylmorphine: A Novel Selective Mu-Opioid Receptor Agonist with High Efficacy and Affinity.

Zádor F, Balogh M, Váradi A, Zádori ZS, Király K, Szűcs E, Varga B, Lázár B, Hosztafi S, Riba P, Benyhe S, Fürst S, Al-Khrasani M.

Eur J Pharmacol. 2017 Nov 5;814:264-273. doi: 10.1016/j.ejphar.2017.08.034. Epub 2017 Aug 30.

PMID:
28864212
11.

Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile.

Stefanucci A, Carotenuto A, Macedonio G, Novellino E, Pieretti S, Marzoli F, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Jul 12;8(8):858-863. doi: 10.1021/acsmedchemlett.7b00210. eCollection 2017 Aug 10.

12.

Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on Migraine.

Nagy-Grócz G, Zádor F, Dvorácskó S, Bohár Z, Benyhe S, Tömböly C, Párdutz Á, Vécsei L.

Int J Mol Sci. 2017 Jul 30;18(8). pii: E1617. doi: 10.3390/ijms18081617. Review.

13.

New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology.

Zádor F, Király K, Váradi A, Balogh M, Fehér Á, Kocsis D, Erdei AI, Lackó E, Zádori ZS, Hosztafi S, Noszál B, Riba P, Benyhe S, Fürst S, Al-Khrasani M.

Eur J Pharmacol. 2017 Aug 15;809:111-121. doi: 10.1016/j.ejphar.2017.05.024. Epub 2017 May 11.

PMID:
28502630
14.

Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.

Stefanucci A, Novellino E, Mirzaie S, Macedonio G, Pieretti S, Minosi P, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Mar 14;8(4):449-454. doi: 10.1021/acsmedchemlett.7b00044. eCollection 2017 Apr 13.

15.

Kynurenic acid and its analogue can alter the opioid receptor G-protein signaling after acute treatment via NMDA receptor in rat cortex and striatum.

Samavati R, Zádor F, Szűcs E, Tuka B, Martos D, Veres G, Gáspár R, Mándity IM, Fülöp F, Vécsei L, Benyhe S, Borsodi A.

J Neurol Sci. 2017 May 15;376:63-70. doi: 10.1016/j.jns.2017.02.053. Epub 2017 Feb 27.

PMID:
28431630
16.

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, Chiavaroli A, Orlando G, Brunetti L, Ferrante C, Pieretti S, Novellino E, Benyhe S, Zador F, Erdei A, Szucs E, Samavati R, Dvrorasko S, Tomboly C, Ragno R, Patsilinakos A, Silvestri R.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):444-451. doi: 10.1080/14756366.2016.1260565.

17.

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates.

Monti L, Stefanucci A, Pieretti S, Marzoli F, Fidanza L, Mollica A, Mirzaie S, Carradori S, De Petrocellis L, Schiano Moriello A, Benyhe S, Zádor F, Szűcs E, Ötvös F, Erdei AI, Samavati R, Dvorácskó S, Tömböly C, Novellino E.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1638-47. doi: 10.3109/14756366.2016.1160902. Epub 2016 Apr 11.

PMID:
27063555
18.

Receptome: Interactions between three pain-related receptors or the "Triumvirate" of cannabinoid, opioid and TRPV1 receptors.

Zádor F, Wollemann M.

Pharmacol Res. 2015 Dec;102:254-63. doi: 10.1016/j.phrs.2015.10.015. Epub 2015 Oct 28. Review.

PMID:
26520391
19.

Further Characterization of Hemopressin Peptide Fragments in the Opioid and Cannabinoid Systems.

Szlavicz E, Perera PS, Tomboly C, Helyes Z, Zador F, Benyhe S, Borsodi A, Bojnik E.

Anesth Analg. 2015 Dec;121(6):1488-94. doi: 10.1213/ANE.0000000000000964.

PMID:
26465932
20.

Inhibition of opioid receptor mediated G-protein activity after chronic administration of kynurenic acid and its derivative without direct binding to opioid receptors.

Zador F, Samavati R, Szlavicz E, Tuka B, Bojnik E, Fulop F, Toldi J, Vecsei L, Borsodi A.

CNS Neurol Disord Drug Targets. 2014;13(9):1520-9.

PMID:
25478797

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