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Items: 16


Monoclonal antibodies with neutralizing activity and Fc-effector functions against the Machupo virus glycoprotein.

Amanat F, Duehr J, Huang C, Paessler S, Tan G, Krammer F.

J Virol. 2019 Dec 4. pii: JVI.01741-19. doi: 10.1128/JVI.01741-19. [Epub ahead of print]


Cross-Reactive Antibodies Binding to the Influenza Virus Subtype H11 Hemagglutinin.

Strohmeier S, Amanat F, Krammer F.

Pathogens. 2019 Oct 21;8(4). pii: E199. doi: 10.3390/pathogens8040199.


Pre-existing anti-neuraminidase antibodies are associated with shortened duration of influenza A (H1N1)pdm virus shedding and illness in naturally infected adults.

Maier HE, Nachbagauer R, Kuan G, Ng S, Lopez R, Sanchez N, Stadlbauer D, Gresh L, Schiller A, Rajabhathor A, Ojeda S, Guglia AF, Amanat F, Balmaseda A, Krammer F, Gordon A.

Clin Infect Dis. 2019 Jul 12. pii: ciz639. doi: 10.1093/cid/ciz639. [Epub ahead of print]


Novel correlates of protection against pandemic H1N1 influenza A virus infection.

Ng S, Nachbagauer R, Balmaseda A, Stadlbauer D, Ojeda S, Patel M, Rajabhathor A, Lopez R, Guglia AF, Sanchez N, Amanat F, Gresh L, Kuan G, Krammer F, Gordon A.

Nat Med. 2019 Jun;25(6):962-967. doi: 10.1038/s41591-019-0463-x. Epub 2019 Jun 3.


Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model.

Amanat F, Meade P, Strohmeier S, Krammer F.

Emerg Microbes Infect. 2019;8(1):155-168. doi: 10.1080/22221751.2018.1564369.


Broadly Cross-Reactive, Nonneutralizing Antibodies against Influenza B Virus Hemagglutinin Demonstrate Effector Function-Dependent Protection against Lethal Viral Challenge in Mice.

Asthagiri Arunkumar G, Ioannou A, Wohlbold TJ, Meade P, Aslam S, Amanat F, Ayllon J, García-Sastre A, Krammer F.

J Virol. 2019 Mar 5;93(6). pii: e01696-18. doi: 10.1128/JVI.01696-18. Print 2019 Mar 15.


Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model.

Stadlbauer D, Amanat F, Strohmeier S, Nachbagauer R, Krammer F.

Emerg Microbes Infect. 2018 Jun 20;7(1):110. doi: 10.1038/s41426-018-0115-0.


Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses.

Amanat F, Duehr J, Oestereich L, Hastie KM, Ollmann Saphire E, Krammer F.

mSphere. 2018 May 2;3(3). pii: e00189-18. doi: 10.1128/mSphere.00189-18. eCollection 2018 May-Jun.


Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.

Wang J, Hilchey SP, DeDiego M, Perry S, Hyrien O, Nogales A, Garigen J, Amanat F, Huertas N, Krammer F, Martinez-Sobrido L, Topham DJ, Treanor JJ, Sangster MY, Zand MS.

PLoS One. 2018 Apr 11;13(4):e0193680. doi: 10.1371/journal.pone.0193680. eCollection 2018.


An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations.

Rajendran M, Sun W, Comella P, Nachbagauer R, Wohlbold TJ, Amanat F, Kirkpatrick E, Palese P, Krammer F.

PLoS One. 2018 Apr 4;13(4):e0194830. doi: 10.1371/journal.pone.0194830. eCollection 2018.


Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans.

Stadlbauer D, Rajabhathor A, Amanat F, Kaplan D, Masud A, Treanor JJ, Izikson R, Cox MM, Nachbagauer R, Krammer F.

mSphere. 2017 Dec 13;2(6). pii: e00502-17. doi: 10.1128/mSphere.00502-17. eCollection 2017 Nov-Dec.


Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes.

Wohlbold TJ, Podolsky KA, Chromikova V, Kirkpatrick E, Falconieri V, Meade P, Amanat F, Tan J, tenOever BR, Tan GS, Subramaniam S, Palese P, Krammer F.

Nat Microbiol. 2017 Oct;2(10):1415-1424. doi: 10.1038/s41564-017-0011-8. Epub 2017 Aug 21.


Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model.

Duehr J, Wohlbold TJ, Oestereich L, Chromikova V, Amanat F, Rajendran M, Gomez-Medina S, Mena I, tenOever BR, García-Sastre A, Basler CF, Munoz-Fontela C, Krammer F.

J Virol. 2017 Jul 27;91(16). pii: e00652-17. doi: 10.1128/JVI.00652-17. Print 2017 Aug 15.


Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model.

Ermler ME, Kirkpatrick E, Sun W, Hai R, Amanat F, Chromikova V, Palese P, Krammer F.

J Virol. 2017 May 26;91(12). pii: e00286-17. doi: 10.1128/JVI.00286-17. Print 2017 Jun 15.


Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin.

Rajendran M, Nachbagauer R, Ermler ME, Bunduc P, Amanat F, Izikson R, Cox M, Palese P, Eichelberger M, Krammer F.

MBio. 2017 Mar 21;8(2). pii: e02281-16. doi: 10.1128/mBio.02281-16.


Hemagglutinin Stalk- and Neuraminidase-Specific Monoclonal Antibodies Protect against Lethal H10N8 Influenza Virus Infection in Mice.

Wohlbold TJ, Chromikova V, Tan GS, Meade P, Amanat F, Comella P, Hirsh A, Krammer F.

J Virol. 2015 Oct 28;90(2):851-61. doi: 10.1128/JVI.02275-15. Print 2016 Jan 15.

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