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Afaq F, Elmets CA.

Photodermatol Photoimmunol Photomed. 2018 Jan;34(1):4. doi: 10.1111/phpp.12369. No abstract available.


Tea polyphenols for the prevention of UVB-induced skin cancer.

Sharma P, Montes de Oca MK, Alkeswani AR, McClees SF, Das T, Elmets CA, Afaq F.

Photodermatol Photoimmunol Photomed. 2018 Jan;34(1):50-59. doi: 10.1111/phpp.12356. Epub 2017 Nov 20. Review.


Potential therapeutic targets of epithelial-mesenchymal transition in melanoma.

Pearlman RL, Montes de Oca MK, Pal HC, Afaq F.

Cancer Lett. 2017 Apr 10;391:125-140. doi: 10.1016/j.canlet.2017.01.029. Epub 2017 Jan 25. Review.


Pomegranate for Prevention and Treatment of Cancer: An Update.

Sharma P, McClees SF, Afaq F.

Molecules. 2017 Jan 24;22(1). pii: E177. doi: 10.3390/molecules22010177. Review.


Phytochemicals for the Prevention of Photocarcinogenesis.

Montes de Oca MK, Pearlman RL, McClees SF, Strickland R, Afaq F.

Photochem Photobiol. 2017 Jul;93(4):956-974. doi: 10.1111/php.12711. Epub 2017 Mar 14. Review.


Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype.

Srivastava RK, Li C, Weng Z, Agarwal A, Elmets CA, Afaq F, Athar M.

Sci Rep. 2016 Oct 11;6:34865. doi: 10.1038/srep34865.


Fisetin and Its Role in Chronic Diseases.

Pal HC, Pearlman RL, Afaq F.

Adv Exp Med Biol. 2016;928:213-244. Review.


ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis.

Srivastava RK, Li C, Ahmad A, Abrams O, Gorbatyuk MS, Harrod KS, Wek RC, Afaq F, Athar M.

Arch Biochem Biophys. 2016 Nov 1;609:39-50. doi: 10.1016/ Epub 2016 Sep 13.


Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.

Li C, Srivastava RK, Weng Z, Croutch CR, Agarwal A, Elmets CA, Afaq F, Athar M.

Am J Pathol. 2016 Oct;186(10):2637-49. doi: 10.1016/j.ajpath.2016.06.012. Epub 2016 Aug 12.


Phytochemicals for the Management of Melanoma.

Pal HC, Hunt KM, Diamond A, Elmets CA, Afaq F.

Mini Rev Med Chem. 2016;16(12):953-79. Review. Erratum in: Mini Rev Med Chem. 2017;17 (15):1500.


Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.

Pal HC, Diamond AC, Strickland LR, Kappes JC, Katiyar SK, Elmets CA, Athar M, Afaq F.

Oncotarget. 2016 Jan 12;7(2):1227-41. doi: 10.18632/oncotarget.6237.


Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells.

Pal HC, Baxter RD, Hunt KM, Agarwal J, Elmets CA, Athar M, Afaq F.

Oncotarget. 2015 Sep 29;6(29):28296-311. doi: 10.18632/oncotarget.5064.


Prodifferentiation, anti-inflammatory and antiproliferative effects of delphinidin, a dietary anthocyanidin, in a full-thickness three-dimensional reconstituted human skin model of psoriasis.

Chamcheu JC, Pal HC, Siddiqui IA, Adhami VM, Ayehunie S, Boylan BT, Noubissi FK, Khan N, Syed DN, Elmets CA, Wood GS, Afaq F, Mukhtar H.

Skin Pharmacol Physiol. 2015;28(4):177-88. doi: 10.1159/000368445. Epub 2015 Jan 22.


Targeting drivers of melanoma with synthetic small molecules and phytochemicals.

Strickland LR, Pal HC, Elmets CA, Afaq F.

Cancer Lett. 2015 Apr 1;359(1):20-35. doi: 10.1016/j.canlet.2015.01.016. Epub 2015 Jan 15. Review.


Fisetin inhibits UVB-induced cutaneous inflammation and activation of PI3K/AKT/NFκB signaling pathways in SKH-1 hairless mice.

Pal HC, Athar M, Elmets CA, Afaq F.

Photochem Photobiol. 2015 Jan-Feb;91(1):225-34. doi: 10.1111/php.12337. Epub 2014 Oct 7.


Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.

Arumugam A, Weng Z, Chaudhary SC, Afaq F, Elmets CA, Athar M.

Biochem Biophys Res Commun. 2014 Aug 29;451(3):394-401. doi: 10.1016/j.bbrc.2014.07.129. Epub 2014 Aug 2.


Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways.

Pal HC, Sharma S, Strickland LR, Katiyar SK, Ballestas ME, Athar M, Elmets CA, Afaq F.

PLoS One. 2014 Jan 23;9(1):e86338. doi: 10.1371/journal.pone.0086338. eCollection 2014.


Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis.

Arumugam A, Weng Z, Talwelkar SS, Chaudhary SC, Kopelovich L, Elmets CA, Afaq F, Athar M.

PLoS One. 2013 Nov 8;8(11):e80076. doi: 10.1371/journal.pone.0080076. eCollection 2013.


Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway.

Chaudhary SC, Singh T, Talwelkar SS, Srivastava RK, Arumugam A, Weng Z, Elmets CA, Afaq F, Kopelovich L, Athar M.

Cancer Prev Res (Phila). 2014 Feb;7(2):186-98. doi: 10.1158/1940-6207.CAPR-13-0276. Epub 2013 Nov 11.


Delphinidin reduces cell proliferation and induces apoptosis of non-small-cell lung cancer cells by targeting EGFR/VEGFR2 signaling pathways.

Pal HC, Sharma S, Strickland LR, Agarwal J, Athar M, Elmets CA, Afaq F.

PLoS One. 2013 Oct 4;8(10):e77270. doi: 10.1371/journal.pone.0077270. eCollection 2013.

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