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Items: 1 to 20 of 33

1.

Marine-Derived Natural Lead Compound Disulfide-Linked Dimer Psammaplin A: Biological Activity and Structural Modification.

Jing Q, Hu X, Ma Y, Mu J, Liu W, Xu F, Li Z, Bai J, Hua H, Li D.

Mar Drugs. 2019 Jun 27;17(7). pii: E384. doi: 10.3390/md17070384. Review.

2.

Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.

Sun Y, Yang J, Liu W, Yao G, Xu F, Hayashi T, Onodera S, Ikejima T.

Mol Cell Biochem. 2019 Jun 10. doi: 10.1007/s11010-019-03572-1. [Epub ahead of print]

PMID:
31183735
3.

Polysaccharide from Okra (Abelmoschus esculentus (L.) Moench) Improves Antioxidant Capacity via PI3K/AKT Pathways and Nrf2 Translocation in a Type 2 Diabetes Model.

Liao Z, Zhang J, Liu B, Yan T, Xu F, Xiao F, Wu B, Bi K, Jia Y.

Molecules. 2019 May 17;24(10). pii: E1906. doi: 10.3390/molecules24101906.

4.

Silibinin's regulation of proliferation and collagen gene expressions of rat pancreatic β-cells cultured on types I and V collagen involves β-catenin nuclear translocation.

Yang J, Sun Y, Liu X, Xu F, Liu W, Hayashi T, Imamura Y, Mizuno K, Hattori S, Tanaka K, Fujisaki H, Tashiro SI, Onodera S, Ikejima T.

Connect Tissue Res. 2019 Sep;60(5):463-476. doi: 10.1080/03008207.2019.1593393. Epub 2019 May 14.

PMID:
30871385
5.

Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation.

Yang J, Sun Y, Xu F, Liu W, Hayashi T, Hattori S, Ushiki-Kaku Y, Onodera S, Tashiro SI, Ikejima T.

Phytother Res. 2019 Apr;33(4):998-1009. doi: 10.1002/ptr.6293. Epub 2019 Feb 6.

PMID:
30729588
6.

Orthogonal test design for optimization of the extraction of essential oil from Asarum heterotropoides var. Mandshuricum and evaluation of its antibacterial activity against periodontal pathogens.

Wang X, Xu F, Zhang H, Peng L, Zhen Y, Wang L, Xu Y, He D, Li X.

3 Biotech. 2018 Nov;8(11):473. doi: 10.1007/s13205-018-1494-6. Epub 2018 Nov 8.

PMID:
30456007
7.

Tectochrysin from Alpinia Oxyphylla Miq. alleviates Aβ1-42 induced learning and memory impairments in mice.

He B, Xu F, Yan T, Xiao F, Wu B, Wang Y, Bi K, Jia Y.

Eur J Pharmacol. 2019 Jan 5;842:365-372. doi: 10.1016/j.ejphar.2018.11.002. Epub 2018 Nov 6.

PMID:
30412728
8.

Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives.

Hu X, Li D, Chu C, Li X, Wang X, Jia Y, Hua H, Xu F.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3403. doi: 10.3390/ijms19113403. Review.

9.

Hydrogen sulfide releasing enmein-type diterpenoid derivatives as apoptosis inducers through mitochondria-related pathways.

Xu F, Gao X, Li H, Xu S, Li X, Hu X, Li Z, Xu J, Hua H, Li D.

Bioorg Chem. 2019 Feb;82:192-203. doi: 10.1016/j.bioorg.2018.10.002. Epub 2018 Oct 8.

PMID:
30326401
10.

Silibinin decreases hepatic glucose production through the activation of gut-brain-liver axis in diabetic rats.

Xu F, Yang J, Negishi H, Sun Y, Li D, Zhang X, Hayashi T, Gao M, Ikeda K, Ikejima T.

Food Funct. 2018 Sep 19;9(9):4926-4935. doi: 10.1039/c8fo00565f.

PMID:
30178798
11.

Diterpenoid lead stevioside and its hydrolysis products steviol and isosteviol: Biological activity and structural modification.

Wang M, Li H, Xu F, Gao X, Li J, Xu S, Zhang D, Wu X, Xu J, Hua H, Li D.

Eur J Med Chem. 2018 Aug 5;156:885-906. doi: 10.1016/j.ejmech.2018.07.052. Epub 2018 Jul 24. Review.

PMID:
30059803
12.

Silibinin ameliorates amylin-induced pancreatic β-cell apoptosis partly via upregulation of GLP-1R/PKA pathway.

Yang J, Sun Y, Xu F, Liu W, Mai Y, Hayashi T, Hattori S, Ushiki-Kaku Y, Onodera S, Tashiro SI, Ikejima T.

Mol Cell Biochem. 2019 Feb;452(1-2):83-94. doi: 10.1007/s11010-018-3414-9. Epub 2018 Jul 18.

PMID:
30022448
13.

Role of silibinin in the management of diabetes mellitus and its complications.

Chu C, Li D, Zhang S, Ikejima T, Jia Y, Wang D, Xu F.

Arch Pharm Res. 2018 Aug;41(8):785-796. doi: 10.1007/s12272-018-1047-x. Epub 2018 Jul 6. Review.

PMID:
29978427
14.

Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer's Disease.

Xu F, He B, Xiao F, Yan T, Bi K, Jia Y, Wang Z.

Biomol Ther (Seoul). 2019 Jan 1;27(1):71-77. doi: 10.4062/biomolther.2018.051.

15.

Antiproliferative hydrogen sulfide releasing evodiamine derivatives and their apoptosis inducing properties.

Hu X, Jiao R, Li H, Wang X, Lyu H, Gao X, Xu F, Li Z, Hua H, Li D.

Eur J Med Chem. 2018 May 10;151:376-388. doi: 10.1016/j.ejmech.2018.04.009. Epub 2018 Apr 4.

PMID:
29635169
16.

Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity.

Yang J, Sun Y, Xu F, Liu W, Hayashi T, Onodera S, Tashiro SI, Ikejima T.

Biomed Pharmacother. 2018 Jun;102:344-353. doi: 10.1016/j.biopha.2018.01.128. Epub 2018 Mar 22.

PMID:
29571019
17.

Novel hybrids of brefeldin A and nitrogen mustards with improved antiproliferative selectivity: Design, synthesis and antitumor biological evaluation.

Han T, Tian K, Pan H, Liu Y, Xu F, Li Z, Uchita T, Gao M, Hua H, Li D.

Eur J Med Chem. 2018 Apr 25;150:53-63. doi: 10.1016/j.ejmech.2018.02.088. Epub 2018 Mar 1.

PMID:
29524728
18.

Engineering Gold Nanorod-Copper Sulfide Heterostructures with Enhanced Photothermal Conversion Efficiency and Photostability.

Leng C, Zhang X, Xu F, Yuan Y, Pei H, Sun Z, Li L, Bao Z.

Small. 2018 Mar;14(12):e1703077. doi: 10.1002/smll.201703077. Epub 2018 Feb 13.

PMID:
29436109
19.

Neuroprotective effects of nootkatone from Alpiniae oxyphyllae Fructus against amyloid-β-induced cognitive impairment.

He B, Xu F, Xiao F, Yan T, Wu B, Bi K, Jia Y.

Metab Brain Dis. 2018 Feb;33(1):251-259. doi: 10.1007/s11011-017-0154-6. Epub 2017 Nov 24.

PMID:
29177693
20.

Design and synthesis of novel nitrogen mustard-evodiamine hybrids with selective antiproliferative activity.

Hu X, Wang Y, Xue J, Han T, Jiao R, Li Z, Liu W, Xu F, Hua H, Li D.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):4989-4993. doi: 10.1016/j.bmcl.2017.10.014. Epub 2017 Oct 7.

PMID:
29037951

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