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Items: 1 to 20 of 149


Relevance of Receptor for Advanced Glycation end Products (RAGE) in Murine Antibody-Mediated Autoimmune Diseases.

Eichhorst A, Daniel C, Rzepka R, Sehnert B, Nimmerjahn F, Voll RE, Chevalier N.

Int J Mol Sci. 2019 Jul 1;20(13). pii: E3234. doi: 10.3390/ijms20133234.


Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?

Schifferli A, Nimmerjahn F, Kühne T.

Front Immunol. 2019 Jun 4;10:1196. doi: 10.3389/fimmu.2019.01196. eCollection 2019. Review.


Two sequential layers of antibody-mediated control of Legionella pneumophila infection.

Weber SS, Stoycheva D, Nimmerjahn F, Oxenius A.

Eur J Immunol. 2019 Sep;49(9):1415-1420. doi: 10.1002/eji.201948106. Epub 2019 Jun 18.


Editorial: Autoantibodies.

Holmdahl R, Nimmerjahn F, Ludwig RJ.

Front Immunol. 2019 Apr 2;10:484. doi: 10.3389/fimmu.2019.00484. eCollection 2019. No abstract available.


Eosinophils Mediate Basophil-Dependent Allergic Skin Inflammation in Mice.

Eberle JU, Radtke D, Nimmerjahn F, Voehringer D.

J Invest Dermatol. 2019 Sep;139(9):1957-1965.e2. doi: 10.1016/j.jid.2019.03.1129. Epub 2019 Mar 22.


Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss.

Grötsch B, Lux A, Rombouts Y, Hoffmann AC, Andreev D, Nimmerjahn F, Xiang W, Scherer HU, Schett G, Bozec A.

J Bone Miner Res. 2019 Jul;34(7):1352-1365. doi: 10.1002/jbmr.3705. Epub 2019 Mar 19.


Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases.

Wannick M, Bezdek S, Guillen N, Thieme M, Meshrkey F, Mousavi S, Seeling M, Nimmerjahn F, Mócsai A, Zillikens D, Sezin T, Sadik CD.

Pharmacol Res Perspect. 2018 Nov 8;6(6):e00438. doi: 10.1002/prp2.438. eCollection 2018 Dec.


IgG-Independent Co-aggregation of FcεRI and FcγRIIB Results in LYN- and SHIP1-Dependent Tyrosine Phosphorylation of FcγRIIB in Murine Bone Marrow-Derived Mast Cells.

Gast M, Preisinger C, Nimmerjahn F, Huber M.

Front Immunol. 2018 Aug 27;9:1937. doi: 10.3389/fimmu.2018.01937. eCollection 2018.


Dissecting FcγR Regulation through a Multivalent Binding Model.

Robinett RA, Guan N, Lux A, Biburger M, Nimmerjahn F, Meyer AS.

Cell Syst. 2018 Jul 25;7(1):41-48.e5. doi: 10.1016/j.cels.2018.05.018. Epub 2018 Jun 27.


CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.

Heger L, Balk S, Lühr JJ, Heidkamp GF, Lehmann CHK, Hatscher L, Purbojo A, Hartmann A, Garcia-Martin F, Nishimura SI, Cesnjevar R, Nimmerjahn F, Dudziak D.

Front Immunol. 2018 Apr 27;9:744. doi: 10.3389/fimmu.2018.00744. eCollection 2018.


Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women.

Engdahl C, Bondt A, Harre U, Raufer J, Pfeifle R, Camponeschi A, Wuhrer M, Seeling M, Mårtensson IL, Nimmerjahn F, Krönke G, Scherer HU, Forsblad-d'Elia H, Schett G.

Arthritis Res Ther. 2018 May 2;20(1):84. doi: 10.1186/s13075-018-1586-z.


More Rules, Still Exceptions: Understanding Immunomodulatory Antibody Activity In Vivo.

Ipsen-Escobedo A, Nimmerjahn F.

Cancer Cell. 2018 Apr 9;33(4):545-546. doi: 10.1016/j.ccell.2018.03.016.


Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice.

Mihai S, Hirose M, Wang Y, Thurman JM, Holers VM, Morgan BP, Köhl J, Zillikens D, Ludwig RJ, Nimmerjahn F.

Front Immunol. 2018 Mar 16;9:535. doi: 10.3389/fimmu.2018.00535. eCollection 2018.


Tolerogenic properties of the Fc portion of IgG and its relevance to the treatment and management of hemophilia

Blumberg RS, Lillicrap D; IgG Fc Immune Tolerance Group.

Blood. 2018 May 17;131(20):2205-2214. doi: 10.1182/blood-2017-12-822908. Epub 2018 Mar 27. Review.


High-resolution definition of humoral immune response correlates of effective immunity against HIV.

Alter G, Dowell KG, Brown EP, Suscovich TJ, Mikhailova A, Mahan AE, Walker BD, Nimmerjahn F, Bailey-Kellogg C, Ackerman ME.

Mol Syst Biol. 2018 Mar 26;14(3):e7881. doi: 10.15252/msb.20177881.


Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB.

Stopforth RJ, Oldham RJ, Tutt AL, Duriez P, Chan HTC, Binkowski BF, Zimprich C, Li D, Hargreaves PG, Cong M, Reddy V, Leandro MJ, Cambridge G, Lux A, Nimmerjahn F, Cragg MS.

J Immunol. 2018 Mar 1;200(5):1937-1950. doi: 10.4049/jimmunol.1700832. Epub 2018 Jan 19.


Sweet SIGNs: IgG glycosylation leads the way in IVIG-mediated resolution of inflammation.

Brückner C, Lehmann C, Dudziak D, Nimmerjahn F.

Int Immunol. 2017 Dec 30;29(11):499-509. doi: 10.1093/intimm/dxx053. Review.


Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions.

Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, Triplett K, Donkor M, Lungu OI, Lux A, Marshall N, Lindorfer MA, Goff OR, Balbino B, Kang TH, Tanno H, Delidakis G, Alford C, Taylor RP, Nimmerjahn F, Varadarajan N, Bruhns P, Zhang YJ, Georgiou G.

Nat Immunol. 2017 Sep 19;18(10):1173. doi: 10.1038/ni1017-1173c. No abstract available.


Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity?

Seeling M, Brückner C, Nimmerjahn F.

Nat Rev Rheumatol. 2017 Oct;13(10):621-630. doi: 10.1038/nrrheum.2017.146. Epub 2017 Sep 14. Review.


Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment.

Heidkamp GF, Sander J, Lehmann CHK, Heger L, Eissing N, Baranska A, Lühr JJ, Hoffmann A, Reimer KC, Lux A, Söder S, Hartmann A, Zenk J, Ulas T, McGovern N, Alexiou C, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Repp R, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Dudziak D.

Sci Immunol. 2016 Dec 16;1(6). pii: eaai7677. doi: 10.1126/sciimmunol.aai7677. Epub 2016 Dec 16.


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