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Items: 1 to 20 of 69


A consensus research agenda for optimising nasal drug delivery.

Forbes B, Bommer R, Goole J, Hellfritzsch M, de Kruijf W, Lambert P, Caivano G, Regard A, Schiaretti F, Trenkel M, Vecellio L, Williams G, Sonvico F, Scherließ R.

Expert Opin Drug Deliv. 2020 Jan 13. doi: 10.1080/17425247.2020.1714589. [Epub ahead of print] No abstract available.


Nasal Drug Delivery of Anticancer Drugs for the Treatment of Glioblastoma: Preclinical and Clinical Trials.

Bruinsmann FA, Richter Vaz G, de Cristo Soares Alves A, Aguirre T, Raffin Pohlmann A, Stanisçuaski Guterres S, Sonvico F.

Molecules. 2019 Nov 26;24(23). pii: E4312. doi: 10.3390/molecules24234312. Review.


Novel O/W nanoemulsions for nasal administration: Structural hints in the selection of performing vehicles with enhanced mucopenetration.

Di Cola E, Cantu' L, Brocca P, Rondelli V, Fadda GC, Canelli E, Martelli P, Clementino A, Sonvico F, Bettini R, Del Favero E.

Colloids Surf B Biointerfaces. 2019 Nov 1;183:110439. doi: 10.1016/j.colsurfb.2019.110439. Epub 2019 Aug 15.


Dry powder inhaler of colistimethate sodium for lung infections in cystic fibrosis: optimization of powder construction.

Kozáková J, Altay A, Ždímal V, Mašková L, Sonvico F, Quarta E, Rossi A, Buttini F, Colombo G.

Drug Dev Ind Pharm. 2019 Oct;45(10):1664-1673. doi: 10.1080/03639045.2019.1652636. Epub 2019 Aug 30.


Ucuùba (Virola surinamensis) Fat-Based Nanostructured Lipid Carriers for Nail Drug Delivery of Ketoconazole: Development and Optimization Using Box-Behnken Design.

Pereira RR, Testi M, Rossi F, Silva Junior JOC, Ribeiro-Costa RM, Bettini R, Santi P, Padula C, Sonvico F.

Pharmaceutics. 2019 Jun 17;11(6). pii: E284. doi: 10.3390/pharmaceutics11060284.


Lipid-core nanocapsules are an alternative to the pulmonary delivery and to increase the stability of statins.

Lorenzoni R, Cordenonsi LM, Davies S, Antonow MB, Medina Diedrich AS, Santos CG, Vitalis GS, Garrastazu G, Buttini F, Sonvico F, Gomes P, Raffin RP.

J Microencapsul. 2019 Jun;36(4):317-326. doi: 10.1080/02652048.2019.1624849. Epub 2019 Jun 19.


Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections.

Rossi I, Buttini F, Sonvico F, Affaticati F, Martinelli F, Annunziato G, Machado D, Viveiros M, Pieroni M, Bettini R.

Pharmaceutics. 2019 May 1;11(5). pii: E203. doi: 10.3390/pharmaceutics11050203.


Chitosan-Coated Nanoparticles: Effect of Chitosan Molecular Weight on Nasal Transmucosal Delivery.

Bruinsmann FA, Pigana S, Aguirre T, Dadalt Souto G, Garrastazu Pereira G, Bianchera A, Tiozzo Fasiolo L, Colombo G, Marques M, Raffin Pohlmann A, Stanisçuaski Guterres S, Sonvico F.

Pharmaceutics. 2019 Feb 18;11(2). pii: E86. doi: 10.3390/pharmaceutics11020086.


Anti-inflammatory flurbiprofen nasal powders for nose-to-brain delivery in Alzheimer's disease.

Tiozzo Fasiolo L, Manniello MD, Bortolotti F, Buttini F, Rossi A, Sonvico F, Colombo P, Valsami G, Colombo G, Russo P.

J Drug Target. 2019 Nov;27(9):984-994. doi: 10.1080/1061186X.2019.1574300. Epub 2019 Feb 11.


Nanoemulsion-Enabled Oral Delivery of Novel Anticancer ω-3 Fatty Acid Derivatives.

Garrastazu Pereira G, Rawling T, Pozzoli M, Pazderka C, Chen Y, Dunstan CR, Murray M, Sonvico F.

Nanomaterials (Basel). 2018 Oct 13;8(10). pii: E825. doi: 10.3390/nano8100825.


Combined hyaluronate-based films loaded with pemetrexed and cisplatin for the treatment of malignant pleural mesothelioma: Preliminary evaluation in an orthotopic tumor recurrence model.

Sonvico F, Barbieri S, Colombo P, Barocelli E, Mucchino C, Cantoni AM, Petronini PG, Rusca M, Carbognani P, Ampollini L.

Eur J Pharm Sci. 2018 Oct 15;123:89-97. doi: 10.1016/j.ejps.2018.07.035. Epub 2018 Jul 17.


Dose administration maneuvers and patient care in tobramycin dry powder inhalation therapy.

Buttini F, Balducci AG, Colombo G, Sonvico F, Montanari S, Pisi G, Rossi A, Colombo P, Bettini R.

Int J Pharm. 2018 Sep 5;548(1):182-191. doi: 10.1016/j.ijpharm.2018.06.006. Epub 2018 Jun 5.


Development and validation of a RP-HPLC method for the simultaneous detection and quantification of simvastatin's isoforms and coenzyme Q10 in lecithin/chitosan nanoparticles.

Clementino A, Sonvico F.

J Pharm Biomed Anal. 2018 Jun 5;155:33-41. doi: 10.1016/j.jpba.2018.03.046. Epub 2018 Mar 23.


Surface-Modified Nanocarriers for Nose-to-Brain Delivery: From Bioadhesion to Targeting.

Sonvico F, Clementino A, Buttini F, Colombo G, Pescina S, Stanisçuaski Guterres S, Raffin Pohlmann A, Nicoli S.

Pharmaceutics. 2018 Mar 15;10(1). pii: E34. doi: 10.3390/pharmaceutics10010034. Review.


Polymeric films loaded with cisplatin for malignant pleural mesothelioma: a pharmacokinetic study in an ovine model.

Ampollini L, Barocelli E, Cavazzoni A, Petronini P, Mucchino C, Cantoni AM, Leonardi F, Ventura L, Barbieri S, Colombo P, Fusari A, Carbognani P, Rusca M, Sonvico F.

J Thorac Dis. 2018 Jan;10(Suppl 2):S207-S220. doi: 10.21037/jtd.2017.10.74.


Physicochemical and pharmacokinetic properties of polymeric films loaded with cisplatin for the treatment of malignant pleural mesothelioma.

Sonvico F, Barbieri S, Colombo P, Mucchino C, Barocelli E, Cantoni AM, Cavazzoni A, Petronini PG, Rusca M, Carbognani P, Ampollini L.

J Thorac Dis. 2018 Jan;10(Suppl 2):S194-S206. doi: 10.21037/jtd.2017.10.12.


In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates.

Giuliani A, Balducci AG, Zironi E, Colombo G, Bortolotti F, Lorenzini L, Galligioni V, Pagliuca G, Scagliarini A, Calzà L, Sonvico F.

Drug Deliv. 2018 Nov;25(1):376-387. doi: 10.1080/10717544.2018.1428242.


Nebulized coenzyme Q10 nanosuspensions: A versatile approach for pulmonary antioxidant therapy.

Rossi I, Sonvico F, McConville JT, Rossi F, Fröhlich E, Zellnitz S, Rossi A, Del Favero E, Bettini R, Buttini F.

Eur J Pharm Sci. 2018 Feb 15;113:159-170. doi: 10.1016/j.ejps.2017.10.024. Epub 2017 Oct 21.


Opportunity and challenges of nasal powders: Drug formulation and delivery.

Tiozzo Fasiolo L, Manniello MD, Tratta E, Buttini F, Rossi A, Sonvico F, Bortolotti F, Russo P, Colombo G.

Eur J Pharm Sci. 2018 Feb 15;113:2-17. doi: 10.1016/j.ejps.2017.09.027. Epub 2017 Sep 20. Review.


Gel-like TPGS-Based Microemulsions for Imiquimod Dermal Delivery: Role of Mesostructure on the Uptake and Distribution into the Skin.

Telò I, Favero ED, Cantù L, Frattini N, Pescina S, Padula C, Santi P, Sonvico F, Nicoli S.

Mol Pharm. 2017 Oct 2;14(10):3281-3289. doi: 10.1021/acs.molpharmaceut.7b00348. Epub 2017 Sep 1.


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