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Items: 1 to 20 of 57


Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer?

Tang M, Svirskis D, Leung E, Kanamala M, Wang H, Wu Z.

J Control Release. 2019 Jul 10;305:89-100. doi: 10.1016/j.jconrel.2019.05.018. Epub 2019 May 13.


Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations.

Leung EY, Askarian-Amiri ME, Singleton DC, Ferraro-Peyret C, Joseph WR, Finlay GJ, Broom RJ, Kakadia PM, Bohlander SK, Marshall E, Baguley BC.

Front Oncol. 2018 Oct 12;8:425. doi: 10.3389/fonc.2018.00425. eCollection 2018.


mRNA transfection by a Xentry-protamine cell-penetrating peptide is enhanced by TLR antagonist E6446.

Bell GD, Yang Y, Leung E, Krissansen GW.

PLoS One. 2018 Jul 30;13(7):e0201464. doi: 10.1371/journal.pone.0201464. eCollection 2018.


A Bioactive l-Phenylalanine-Derived Arene in Multitargeted Organoruthenium Compounds: Impact on the Antiproliferative Activity and Mode of Action.

Movassaghi S, Leung E, Hanif M, Lee BYT, Holtkamp HU, Tu JKY, Söhnel T, Jamieson SMF, Hartinger CG.

Inorg Chem. 2018 Jul 16;57(14):8521-8529. doi: 10.1021/acs.inorgchem.8b01187. Epub 2018 Jun 27.


Correction: Sarkar, D., et al. Multiple Isoforms of ANRIL in Melanoma Cells: Structural Complexity Suggests Variations in Processing. Int. J. Mol. Sci. 2017, 18, 1378.

Sarkar D, Oghabian A, Bodiyabadu PK, Joseph WR, Leung EY, Finlay GJ, Baguley BC, Askarian-Amiri ME.

Int J Mol Sci. 2018 May 2;19(5). pii: E1343. doi: 10.3390/ijms19051343. No abstract available.


Clinical Implications of Digenic Inheritance and Epistasis in Primary Immunodeficiency Disorders.

Ameratunga R, Woon ST, Bryant VL, Steele R, Slade C, Leung EY, Lehnert K.

Front Immunol. 2018 Jan 26;8:1965. doi: 10.3389/fimmu.2017.01965. eCollection 2017.


HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells.

Huang WT, Tsai YH, Chen SH, Kuo CW, Kuo YL, Lee KT, Chen WC, Wu PC, Chuang CY, Cheng SM, Lin CH, Leung EY, Chang YC, Cheung CHA.

Front Pharmacol. 2017 Dec 13;8:902. doi: 10.3389/fphar.2017.00902. eCollection 2017.


Investigation into Improving the Aqueous Solubility of the Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Zafar A, Pilkington LI, Haverkate NA, van Rensburg M, Leung E, Kumara S, Denny WA, Barker D, Alsuraifi A, Hoskins C, Reynisson J.

Molecules. 2018 Jan 11;23(1). pii: E145. doi: 10.3390/molecules23010145.


GPCR Modulation of Thieno[2,3-b]pyridine Anti-Proliferative Agents.

Zafar A, Sari S, Leung E, Pilkington LI, van Rensburg M, Barker D, Reynisson J.

Molecules. 2017 Dec 18;22(12). pii: E2254. doi: 10.3390/molecules22122254.


Epistatic interactions between mutations of TACI (TNFRSF13B) and TCF3 result in a severe primary immunodeficiency disorder and systemic lupus erythematosus.

Ameratunga R, Koopmans W, Woon ST, Leung E, Lehnert K, Slade CA, Tempany JC, Enders A, Steele R, Browett P, Hodgkin PD, Bryant VL.

Clin Transl Immunology. 2017 Oct 20;6(10):e159. doi: 10.1038/cti.2017.41. eCollection 2017 Oct.


Endocrine Therapy of Estrogen Receptor-Positive Breast Cancer Cells: Early Differential Effects on Stem Cell Markers.

Leung EY, Askarian-Amiri ME, Sarkar D, Ferraro-Peyret C, Joseph WR, Finlay GJ, Baguley BC.

Front Oncol. 2017 Sep 4;7:184. doi: 10.3389/fonc.2017.00184. eCollection 2017.


Multiple Isoforms of ANRIL in Melanoma Cells: Structural Complexity Suggests Variations in Processing.

Sarkar D, Oghabian A, Bodiyabadu PK, Joseph WR, Leung EY, Finlay GJ, Baguley BC, Askarian-Amiri ME.

Int J Mol Sci. 2017 Jun 27;18(7). pii: E1378. doi: 10.3390/ijms18071378. Erratum in: Int J Mol Sci. 2018 May 02;19(5):.


Glycophenotype of breast and prostate cancer stem cells treated with thieno[2,3-b]pyridine anticancer compound.

Mastelić A, Čikeš Čulić V, Režić Mužinić N, Vuica-Ross M, Barker D, Leung EY, Reynisson J, Markotić A.

Drug Des Devel Ther. 2017 Mar 14;11:759-769. doi: 10.2147/DDDT.S121122. eCollection 2017.


Synthesis and antiproliferative activity of 2-chlorophenyl carboxamide thienopyridines.

van Rensburg M, Leung E, Haverkate NA, Eurtivong C, Pilkington LI, Reynisson J, Barker D.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):135-138. doi: 10.1016/j.bmcl.2016.12.009. Epub 2016 Dec 5.


ZFAS1: a long noncoding RNA associated with ribosomes in breast cancer cells.

Hansji H, Leung EY, Baguley BC, Finlay GJ, Cameron-Smith D, Figueiredo VC, Askarian-Amiri ME.

Biol Direct. 2016 Nov 21;11(1):62.


Selected GRIN2A mutations in melanoma cause oncogenic effects that can be modulated by extracellular glutamate.

D'mello SA, Joseph WR, Green TN, Leung EY, During MJ, Finlay GJ, Baguley BC, Kalev-Zylinska ML.

Cell Calcium. 2016 Dec;60(6):384-395. doi: 10.1016/j.ceca.2016.09.003. Epub 2016 Sep 14.


Synthesis and biological activity of pyrrole analogues of combretastatin A-4.

Jung EK, Leung E, Barker D.

Bioorg Med Chem Lett. 2016 Jul 1;26(13):3001-3005. doi: 10.1016/j.bmcl.2016.05.026. Epub 2016 May 10.


Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells.

Lee JY, Kuo CW, Tsai SL, Cheng SM, Chen SH, Chan HH, Lin CH, Lin KY, Li CF, Kanwar JR, Leung EY, Cheung CC, Huang WJ, Wang YC, Cheung CH.

Front Pharmacol. 2016 Mar 31;7:81. doi: 10.3389/fphar.2016.00081. eCollection 2016.


Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative.

Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY.

Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016.


The Regulatory Role of Long Noncoding RNAs in Cancer Drug Resistance.

Askarian-Amiri ME, Leung E, Finlay G, Baguley BC.

Methods Mol Biol. 2016;1395:207-27. doi: 10.1007/978-1-4939-3347-1_12. Review.


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