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Items: 1 to 20 of 574

1.

Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication.

Merlino F, Tomassi S, Yousif AM, Messere A, Marinelli L, Grieco P, Novellino E, Cosconati S, Di Maro S.

Org Lett. 2019 Aug 16;21(16):6378-6382. doi: 10.1021/acs.orglett.9b02283. Epub 2019 Jul 30.

PMID:
31361506
2.

Polyphenols: A concise overview on the chemistry, occurrence, and human health.

Durazzo A, Lucarini M, Souto EB, Cicala C, Caiazzo E, Izzo AA, Novellino E, Santini A.

Phytother Res. 2019 Jul 29. doi: 10.1002/ptr.6419. [Epub ahead of print] Review.

PMID:
31359516
3.

Online comprehensive hydrophilic interaction chromatography × reversed phase liquid chromatography coupled to mass spectrometry for in depth peptidomic profile of microalgae gastro-intestinal digests.

Sommella E, Salviati E, Merciai F, Manfra M, Bertamino A, Gasparrini F, Novellino E, Campiglia P.

J Pharm Biomed Anal. 2019 Jul 19;175:112783. doi: 10.1016/j.jpba.2019.112783. [Epub ahead of print]

PMID:
31352169
4.

Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations.

Bruno A, Barresi E, Simola N, Da Pozzo E, Costa B, Novellino E, Da Settimo F, Martini C, Taliani S, Cosconati S.

ACS Chem Neurosci. 2019 Aug 21;10(8):3805-3814. doi: 10.1021/acschemneuro.9b00300. Epub 2019 Jul 3.

PMID:
31268683
5.

Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives.

Pelliccia S, Amato J, Capasso D, Di Gaetano S, Massarotti A, Piccolo M, Irace C, Tron GC, Pagano B, Randazzo A, Novellino E, Giustiniano M.

J Med Chem. 2019 Jul 10. doi: 10.1021/acs.jmedchem.9b00262. [Epub ahead of print]

PMID:
31241946
6.

Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: A critical review of in vitro and in vivo animal-based studies.

Annunziata G, Barrea L, Ciampaglia R, Cicala C, Arnone A, Savastano S, Nabavi SM, Tenore GC, Novellino E.

Phytother Res. 2019 Jun 24. doi: 10.1002/ptr.6416. [Epub ahead of print] Review.

PMID:
31232489
7.

Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II).

D'Alessandro S, Alfano G, Di Cerbo L, Brogi S, Chemi G, Relitti N, Brindisi M, Lamponi S, Novellino E, Campiani G, Gemma S, Basilico N, Taramelli D, Baratto MC, Pogni R, Butini S.

Bioorg Chem. 2019 Aug;89:103020. doi: 10.1016/j.bioorg.2019.103020. Epub 2019 May 31.

PMID:
31185392
8.

Identification of novel indole derivatives acting as inhibitors of the Keap1-Nrf2 interaction.

Cosimelli B, Greco G, Laneri S, Novellino E, Sacchi A, Amendola G, Cosconati S, Bortolozzi R, Viola G.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1152-1157. doi: 10.1080/14756366.2019.1623209.

9.

Effect of Grape Pomace Polyphenols With or Without Pectin on TMAO Serum Levels Assessed by LC/MS-Based Assay: A Preliminary Clinical Study on Overweight/Obese Subjects.

Annunziata G, Maisto M, Schisano C, Ciampaglia R, Narciso V, Hassan STS, Tenore GC, Novellino E.

Front Pharmacol. 2019 May 21;10:575. doi: 10.3389/fphar.2019.00575. eCollection 2019.

10.

Fruit-based juices: Focus on antioxidant properties-Study approach and update.

Durazzo A, Lucarini M, Novellino E, Daliu P, Santini A.

Phytother Res. 2019 Jul;33(7):1754-1769. doi: 10.1002/ptr.6380. Epub 2019 Jun 2. Review.

PMID:
31155809
11.

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines.

Galli U, Hysenlika R, Meneghetti F, Del Grosso E, Pelliccia S, Novellino E, Giustiniano M, Tron GC.

Molecules. 2019 May 21;24(10). pii: E1959. doi: 10.3390/molecules24101959.

12.

The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L.

Buommino E, Carotenuto A, Antignano I, Bellavita R, Casciaro B, Loffredo MR, Merlino F, Novellino E, Mangoni ML, Nocera FP, Brancaccio D, Punzi P, Roversi D, Ingenito R, Bianchi E, Grieco P.

ChemMedChem. 2019 Jul 3;14(13):1283-1290. doi: 10.1002/cmdc.201900221. Epub 2019 Jun 3.

PMID:
31087626
13.

Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study.

Iaccarino N, Amato J, Pagano B, Di Porzio A, Micucci M, Bolelli L, Aldini R, Novellino E, Budriesi R, Randazzo A.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1041-1050. doi: 10.1080/14756366.2019.1611802.

14.

Antioxidant Properties of Four Commonly Consumed Popular Italian Dishes.

Durazzo A, Lucarini M, Santini A, Camilli E, Gabrielli P, Marconi S, Lisciani S, Aguzzi A, Gambelli L, Novellino E, Marletta L.

Molecules. 2019 Apr 19;24(8). pii: E1543. doi: 10.3390/molecules24081543.

15.

Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.

De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A.

ACS Med Chem Lett. 2019 Feb 4;10(4):469-474. doi: 10.1021/acsmedchemlett.8b00507. eCollection 2019 Apr 11.

PMID:
30996781
16.

Discovery of Pyrido[3',2':5,6]thiopyrano[4,3-d]pyrimidine-Based Antiproliferative Multikinase Inhibitors.

Salerno S, Barresi E, García-Argáez AN, Taliani S, Simorini F, Amendola G, Tomassi S, Cosconati S, Novellino E, Da Settimo F, Marini AM, Dalla Via L.

ACS Med Chem Lett. 2019 Jan 17;10(4):457-462. doi: 10.1021/acsmedchemlett.8b00499. eCollection 2019 Apr 11.

PMID:
30996779
17.

Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: in Vivo and in Vitro Biological Profile.

Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A.

ACS Med Chem Lett. 2019 Mar 8;10(4):450-456. doi: 10.1021/acsmedchemlett.8b00495. eCollection 2019 Apr 11.

PMID:
30996778
18.

Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.

Sepe V, Marchianò S, Finamore C, Baronissi G, Di Leva FS, Carino A, Biagioli M, Fiorucci C, Cassiano C, Monti MC, Del Gaudio F, Novellino E, Limongelli V, Fiorucci S, Zampella A.

ACS Med Chem Lett. 2018 Dec 6;10(4):407-412. doi: 10.1021/acsmedchemlett.8b00423. eCollection 2019 Apr 11.

PMID:
30996771
19.

On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity.

Stefanucci A, Lei W, Pieretti S, Novellino E, Dimmito MP, Marzoli F, Streicher JM, Mollica A.

Sci Rep. 2019 Apr 8;9(1):5771. doi: 10.1038/s41598-019-42289-5.

20.

The acute myeloid leukemia-associated Nucleophosmin 1 gene mutations dictate amyloidogenicity of the C-terminal domain.

La Manna S, Scognamiglio PL, Roviello V, Borbone F, Florio D, Di Natale C, Bigi A, Cecchi C, Cascella R, Giannini C, Sibillano T, Novellino E, Marasco D.

FEBS J. 2019 Jun;286(12):2311-2328. doi: 10.1111/febs.14815. Epub 2019 Apr 8.

PMID:
30921500

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