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Reperfusion Arrhythmias Increase after Superior Cervical Ganglionectomy Due to Conduction Disorders and Changes in Repolarization.

Prado NJ, Muñoz EM, Farias Altamirano LE, Aguiar F, Ponce Zumino AZ, Sánchez FJ, Miatello RM, Pueyo E, Diez ER.

Int J Mol Sci. 2020 Mar 6;21(5). pii: E1804. doi: 10.3390/ijms21051804.


Conditional KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.

Lozano-Gerona J, Oliván-Viguera A, Delgado-Wicke P, Singh V, Brown BM, Tapia-Casellas E, Pueyo E, Valero MS, Garcia-Otín ÁL, Giraldo P, Abarca-Lachen E, Surra JC, Osada J, Hamilton KL, Raychaudhuri SP, Marigil M, Juarranz Á, Wulff H, Miura H, Gilaberte Y, Köhler R.

PLoS One. 2020 Mar 9;15(3):e0222619. doi: 10.1371/journal.pone.0222619. eCollection 2020.


The 'Digital Twin' to enable the vision of precision cardiology.

Corral-Acero J, Margara F, Marciniak M, Rodero C, Loncaric F, Feng Y, Gilbert A, Fernandes JF, Bukhari HA, Wajdan A, Martinez MV, Santos MS, Shamohammdi M, Luo H, Westphal P, Leeson P, DiAchille P, Gurev V, Mayr M, Geris L, Pathmanathan P, Morrison T, Cornelussen R, Prinzen F, Delhaas T, Doltra A, Sitges M, Vigmond EJ, Zacur E, Grau V, Rodriguez B, Remme EW, Niederer S, Mortier P, McLeod K, Potse M, Pueyo E, Bueno-Orovio A, Lamata P.

Eur Heart J. 2020 Mar 4. pii: ehaa159. doi: 10.1093/eurheartj/ehaa159. [Epub ahead of print]


Complex Interaction Between Low-Frequency APD Oscillations and Beat-to-Beat APD Variability in Humans Is Governed by the Sympathetic Nervous System.

Duijvenboden SV, Porter B, Pueyo E, Sampedro-Puente DA, Fernandez-Bes J, Sidhu B, Gould J, Orini M, Bishop MJ, Hanson B, Lambiase P, Razavi R, Rinaldi CA, Gill JS, Taggart P.

Front Physiol. 2020 Jan 22;10:1582. doi: 10.3389/fphys.2019.01582. eCollection 2019.


Time Course of Low-Frequency Oscillatory Behavior in Human Ventricular Repolarization Following Enhanced Sympathetic Activity and Relation to Arrhythmogenesis.

Sampedro-Puente DA, Fernandez-Bes J, Szentandrássy N, Nánási P, Taggart P, Pueyo E.

Front Physiol. 2020 Jan 14;10:1547. doi: 10.3389/fphys.2019.01547. eCollection 2019.


Long-Term Microgravity Exposure Increases ECG Repolarization Instability Manifested by Low-Frequency Oscillations of T-Wave Vector.

Palacios S, Caiani EG, Landreani F, Martínez JP, Pueyo E.

Front Physiol. 2019 Dec 17;10:1510. doi: 10.3389/fphys.2019.01510. eCollection 2019.


Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics.

Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M, Munroe PB.

Circ Arrhythm Electrophysiol. 2019 Oct;12(10):e007549. doi: 10.1161/CIRCEP.119.007549. Epub 2019 Oct 14.


Mechanisms Underlying Interactions Between Low-Frequency Oscillations and Beat-to-Beat Variability of Celullar Ventricular Repolarization in Response to Sympathetic Stimulation: Implications for Arrhythmogenesis.

Sampedro-Puente DA, Fernandez-Bes J, Porter B, van Duijvenboden S, Taggart P, Pueyo E.

Front Physiol. 2019 Aug 2;10:916. doi: 10.3389/fphys.2019.00916. eCollection 2019.


Data-Driven Identification of Stochastic Model Parameters and State Variables: Application to the Study of Cardiac Beat-to-Beat Variability.

Sampedro-Puente DA, Fernandez-Bes J, Virag L, Varro A, Pueyo E.

IEEE J Biomed Health Inform. 2020 Mar;24(3):693-704. doi: 10.1109/JBHI.2019.2921881. Epub 2019 Jun 10.


KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility.

Valero MS, Ramón-Gimenez M, Lozano-Gerona J, Delgado-Wicke P, Calmarza P, Oliván-Viguera A, López V, Garcia-Otín ÁL, Valero S, Pueyo E, Hamilton KL, Miura H, Köhler R.

Int J Mol Sci. 2019 Mar 8;20(5). pii: E1193. doi: 10.3390/ijms20051193.


Corrigendum to "Limitations in electrophysiological model development and validation caused by differences between simulations and experimental protocols" [Prog. Biophys. Mol. Biol. 129 (2017) 53-64].

Carro J, Rodríguez-Matas JF, Monasterio V, Pueyo E.

Prog Biophys Mol Biol. 2018 Dec;140:175. doi: 10.1016/j.pbiomolbio.2018.11.001. Epub 2018 Nov 15. No abstract available.


A response surface optimization approach to adjust ionic current conductances of cardiac electrophysiological models. Application to the study of potassium level changes.

Carro J, Pueyo E, Rodríguez Matas JF.

PLoS One. 2018 Oct 3;13(10):e0204411. doi: 10.1371/journal.pone.0204411. eCollection 2018.


Editorial: Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond.

Grandi E, Morotti S, Pueyo E, Rodriguez B.

Front Physiol. 2018 Jun 8;9:678. doi: 10.3389/fphys.2018.00678. eCollection 2018. No abstract available.


Corrigendum: Influence of Heart Rate in Non-linear HRV Indices as a Sampling Rate Effect Evaluated on Supine and Standing.

Bolea J, Pueyo E, Orini M, Bailón R.

Front Physiol. 2018 May 28;9:620. doi: 10.3389/fphys.2018.00620. eCollection 2018.


Corrigendum to "Interactive effect of beta-adrenergic stimulation and mechanical stretch on low-frequency oscillations of ventricular action potential duration in humans" [J. Mol. Cell. Cardiol. 97 (2016) 93-105].

Pueyo E, Orini M, Rodríguez JF, Taggart P.

J Mol Cell Cardiol. 2018 Aug;121:305. doi: 10.1016/j.yjmcc.2018.05.006. Epub 2018 May 21. No abstract available.


Correction: Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.

Vicente J, Johannesen L, Hosseini M, Mason JW, Sager PT, Pueyo E, Strauss DG.

PLoS One. 2018 May 21;13(5):e0197952. doi: 10.1371/journal.pone.0197952. eCollection 2018.


Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.

Olivan-Viguera A, Garcia-Otin AL, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis AJ, Hamilton KL, Gilaberte Y, Pueyo E, Köhler R.

PLoS One. 2018 Jan 2;13(1):e0190307. doi: 10.1371/journal.pone.0190307. eCollection 2018.


Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model.

Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, Bayés de Luna A, Martínez JP, Laguna P, Pueyo E.

PLoS One. 2017 Oct 11;12(10):e0186152. doi: 10.1371/journal.pone.0186152. eCollection 2017.


A Time-Varying Nonparametric Methodology for Assessing Changes in QT Variability Unrelated to Heart Rate Variability.

Orini M, Pueyo E, Laguna P, Bailon R.

IEEE Trans Biomed Eng. 2018 Jul;65(7):1443-1451. doi: 10.1109/TBME.2017.2758925. Epub 2017 Oct 6.


Pulse Rate and Transit Time Analysis to Predict Hypotension Events After Spinal Anesthesia During Programmed Cesarean Labor.

Bolea J, Lázaro J, Gil E, Rovira E, Remartínez JM, Laguna P, Pueyo E, Navarro A, Bailón R.

Ann Biomed Eng. 2017 Sep;45(9):2253-2263. doi: 10.1007/s10439-017-1864-y. Epub 2017 Jul 11.


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