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Items: 1 to 20 of 45

1.

Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors.

López-Ureña D, Orozco-Aguilar J, Chaves-Madrigal Y, Ramírez-Mata A, Villalobos-Jimenez A, Ost S, Quesada-Gómez C, Rodríguez C, Papatheodorou P, Chaves-Olarte E.

Toxins (Basel). 2019 Jun 17;11(6). pii: E348. doi: 10.3390/toxins11060348.

2.

Neutrophils as Trojan Horse Vehicles for Brucella abortus Macrophage Infection.

Gutiérrez-Jiménez C, Mora-Cartín R, Altamirano-Silva P, Chacón-Díaz C, Chaves-Olarte E, Moreno E, Barquero-Calvo E.

Front Immunol. 2019 May 7;10:1012. doi: 10.3389/fimmu.2019.01012. eCollection 2019.

3.

Neutrophils Dampen Adaptive Immunity in Brucellosis.

Mora-Cartín R, Gutiérrez-Jiménez C, Alfaro-Alarcón A, Chaves-Olarte E, Chacón-Díaz C, Barquero-Calvo E, Moreno E.

Infect Immun. 2019 Apr 23;87(5). pii: e00118-19. doi: 10.1128/IAI.00118-19. Print 2019 Mar.

4.

Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.

Papatheodorou P, Song S, López-Ureña D, Witte A, Marques F, Ost GS, Schorch B, Chaves-Olarte E, Aktories K.

FASEB J. 2019 Apr;33(4):4883-4892. doi: 10.1096/fj.201801440R. Epub 2018 Dec 28.

PMID:
30592645
5.

Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements.

Ramírez-Vargas G, López-Ureña D, Badilla A, Orozco-Aguilar J, Murillo T, Rojas P, Riedel T, Overmann J, González G, Chaves-Olarte E, Quesada-Gómez C, Rodríguez C.

Sci Rep. 2018 Sep 17;8(1):13951. doi: 10.1038/s41598-018-32390-6.

6.

Depletion of Complement Enhances the Clearance of Brucella abortus in Mice.

González-Espinoza G, Barquero-Calvo E, Lizano-González E, Alfaro-Alarcón A, Arias-Gómez B, Chaves-Olarte E, Lomonte B, Moreno E, Chacón-Díaz C.

Infect Immun. 2018 Sep 21;86(10). pii: e00567-18. doi: 10.1128/IAI.00567-18. Print 2018 Oct.

7.

Two Groups of Cocirculating, Epidemic Clostridiodes difficile Strains Microdiversify through Different Mechanisms.

Murillo T, Ramírez-Vargas G, Riedel T, Overmann J, Andersen JM, Guzmán-Verri C, Chaves-Olarte E, Rodríguez C.

Genome Biol Evol. 2018 Mar 1;10(3):982-998. doi: 10.1093/gbe/evy059.

8.

Brucella abortus Senses the Intracellular Environment through the BvrR/BvrS Two-Component System, Which Allows B. abortus To Adapt to Its Replicative Niche.

Altamirano-Silva P, Meza-Torres J, Castillo-Zeledón A, Ruiz-Villalobos N, Zuñiga-Pereira AM, Chacón-Díaz C, Moreno E, Guzmán-Verri C, Chaves-Olarte E.

Infect Immun. 2018 Mar 22;86(4). pii: e00713-17. doi: 10.1128/IAI.00713-17. Print 2018 Apr.

9.

Brucellosis caused by the wood rat pathogen Brucella neotomae: two case reports.

Villalobos-Vindas JM, Amuy E, Barquero-Calvo E, Rojas N, Chacón-Díaz C, Chaves-Olarte E, Guzman-Verri C, Moreno E.

J Med Case Rep. 2017 Dec 19;11(1):352. doi: 10.1186/s13256-017-1496-8.

10.

Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution.

Suárez-Esquivel M, Baker KS, Ruiz-Villalobos N, Hernández-Mora G, Barquero-Calvo E, González-Barrientos R, Castillo-Zeledón A, Jiménez-Rojas C, Chacón-Díaz C, Cloeckaert A, Chaves-Olarte E, Thomson NR, Moreno E, Guzmán-Verri C.

Genome Biol Evol. 2017 Jul 1;9(7):1901-1912. doi: 10.1093/gbe/evx137.

11.

Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease.

Hernández-Mora G, Ruiz-Villalobos N, Bonilla-Montoya R, Romero-Zúniga JJ, Jiménez-Arias J, González-Barrientos R, Barquero-Calvo E, Chacón-Díaz C, Rojas N, Chaves-Olarte E, Guzmán-Verri C, Moreno E.

PLoS One. 2017 Aug 10;12(8):e0182380. doi: 10.1371/journal.pone.0182380. eCollection 2017.

12.

Brucellosis in mammals of Costa Rica: An epidemiological survey.

Hernández-Mora G, Bonilla-Montoya R, Barrantes-Granados O, Esquivel-Suárez A, Montero-Caballero D, González-Barrientos R, Fallas-Monge Z, Palacios-Alfaro JD, Baldi M, Campos E, Chanto G, Barquero-Calvo E, Chacón-Díaz C, Chaves-Olarte E, Guzmán Verri C, Romero-Zúñiga JJ, Moreno E.

PLoS One. 2017 Aug 9;12(8):e0182644. doi: 10.1371/journal.pone.0182644. eCollection 2017.

13.

Brucella neotomae Infection in Humans, Costa Rica.

Suárez-Esquivel M, Ruiz-Villalobos N, Jiménez-Rojas C, Barquero-Calvo E, Chacón-Díaz C, Víquez-Ruiz E, Rojas-Campos N, Baker KS, Oviedo-Sánchez G, Amuy E, Chaves-Olarte E, Thomson NR, Moreno E, Guzmán-Verri C.

Emerg Infect Dis. 2017 Jun;23(6):997-1000. doi: 10.3201/eid2306.162018. Erratum in: Emerg Infect Dis. 2017 Aug;23(8):1435.

14.

A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements.

Ramírez-Vargas G, Quesada-Gómez C, Acuña-Amador L, López-Ureña D, Murillo T, Del Mar Gamboa-Coronado M, Chaves-Olarte E, Thomson N, Rodríguez-Cavallini E, Rodríguez C.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02054-16. doi: 10.1128/AAC.02054-16. Print 2017 Apr.

15.

Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains.

Suárez-Esquivel M, Ruiz-Villalobos N, Castillo-Zeledón A, Jiménez-Rojas C, Roop Ii RM, Comerci DJ, Barquero-Calvo E, Chacón-Díaz C, Caswell CC, Baker KS, Chaves-Olarte E, Thomson NR, Moreno E, Letesson JJ, De Bolle X, Guzmán-Verri C.

Front Microbiol. 2016 Sep 29;7:1557. eCollection 2016.

16.

Clostridium difficile Infection.

Shin JH, Chaves-Olarte E, Warren CA.

Microbiol Spectr. 2016 Jun;4(3). doi: 10.1128/microbiolspec.EI10-0007-2015. Review.

PMID:
27337475
17.

A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption.

Costa CL, López-Ureña D, de Oliveira Assis T, Ribeiro RA, Silva RO, Rupnik M, Wilcox MH, de Carvalho AF, do Carmo AO, Dias AA, de Carvalho CB, Chaves-Olarte E, Rodríguez C, Quesada-Gómez C, de Castro Brito GA.

Anaerobe. 2016 Aug;40:76-84. doi: 10.1016/j.anaerobe.2016.06.005. Epub 2016 Jun 14.

18.

N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils.

Mora-Cartín R, Chacón-Díaz C, Gutiérrez-Jiménez C, Gurdián-Murillo S, Lomonte B, Chaves-Olarte E, Barquero-Calvo E, Moreno E.

Infect Immun. 2016 May 24;84(6):1712-21. doi: 10.1128/IAI.00137-16. Print 2016 Jun.

19.

Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.

Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E.

Infect Immun. 2016 Jan 11;84(3):856-65. doi: 10.1128/IAI.01291-15.

20.

Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts.

Chacón-Díaz C, Altamirano-Silva P, González-Espinoza G, Medina MC, Alfaro-Alarcón A, Bouza-Mora L, Jiménez-Rojas C, Wong M, Barquero-Calvo E, Rojas N, Guzmán-Verri C, Moreno E, Chaves-Olarte E.

Infect Immun. 2015 Dec;83(12):4861-70. doi: 10.1128/IAI.00995-15. Epub 2015 Oct 5.

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