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Items: 1 to 20 of 52

1.

Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis.

Simón Serrano S, Grönberg A, Longato L, Rombouts K, Kuo J, Gregory M, Moss S, Elmér E, Mazza G, Gallay P, Pinzani M, Hansson MJ, Massoumi R.

Cells. 2019 Nov 8;8(11). pii: E1409. doi: 10.3390/cells8111409.

2.

Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice.

Tomašić N, Kotarsky H, de Oliveira Figueiredo R, Hansson E, Mörgelin M, Tomašić I, Kallijärvi J, Elmér E, Jauhiainen M, Eklund EA, Fellman V.

Biochim Biophys Acta Mol Basis Dis. 2020 Jan 1;1866(1):165573. doi: 10.1016/j.bbadis.2019.165573. Epub 2019 Oct 29.

PMID:
31672551
3.

Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients.

Kelsen J, Karlsson M, Hansson MJ, Yang Z, Fischer W, Hugerth M, Nordström CH, Åstrand R, Keep MF, Kilbaugh T, Wang KKW, Møller K, Juhler M, Elmér E.

J Neurotrauma. 2019 Dec 1;36(23):3253-3263. doi: 10.1089/neu.2018.6369. Epub 2019 Aug 1.

4.

Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production.

Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ.

Intensive Care Med Exp. 2018 Aug 1;6(1):22. doi: 10.1186/s40635-018-0186-1.

5.

Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury.

Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T.

J Neurotrauma. 2018 Jul 24. doi: 10.1089/neu.2018.5706. [Epub ahead of print]

6.

Effect and Safety of Morphine Use in Acute Anterior ST-Segment Elevation Myocardial Infarction.

Bonin M, Mewton N, Roubille F, Morel O, Cayla G, Angoulvant D, Elbaz M, Claeys MJ, Garcia-Dorado D, Giraud C, Rioufol G, Jossan C, Ovize M, Guerin P; CIRCUS Study Investigators.

J Am Heart Assoc. 2018 Feb 10;7(4). pii: e006833. doi: 10.1161/JAHA.117.006833.

7.

Cyclosporine before Coronary Artery Bypass Grafting Does Not Prevent Postoperative Decreases in Renal Function: A Randomized Clinical Trial.

Ederoth P, Dardashti A, Grins E, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H.

Anesthesiology. 2018 Apr;128(4):710-717. doi: 10.1097/ALN.0000000000002104. Erratum in: Anesthesiology. 2019 Feb;130(2):360.

PMID:
29369890
8.

Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease.

Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E.

Pediatr Res. 2018 Feb;83(2):455-465. doi: 10.1038/pr.2017.250. Epub 2017 Nov 15.

PMID:
28981487
9.

Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model.

Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V.

Orphanet J Rare Dis. 2017 Apr 20;12(1):73. doi: 10.1186/s13023-017-0624-2.

10.

Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): a study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study.

Ederoth P, Grins E, Dardashti A, Brondén B, Metzsch C, Erdling A, Nozohoor S, Mokhtari A, Hansson MJ, Elmér E, Algotsson L, Jovinge S, Bjursten H.

BMJ Open. 2016 Dec 15;6(12):e012299. doi: 10.1136/bmjopen-2016-012299.

11.

Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction - An in vivo large animal model.

Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E.

Mitochondrion. 2016 Nov;31:56-62. doi: 10.1016/j.mito.2016.10.003. Epub 2016 Oct 18.

PMID:
27769952
12.

Retraction Note: Brain injury following cardiac arrest: pathophysiology for neurocritical care.

Uchino H, Ogihara Y, Fukui H, Chijiiwa M, Sekine S, Hara N, Elmér E.

J Intensive Care. 2016 Sep 20;4:61. doi: 10.1186/s40560-016-0185-9. eCollection 2016.

13.

Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.

Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E.

Nat Commun. 2016 Aug 9;7:12317. doi: 10.1038/ncomms12317.

14.

White Adipose Tissue Browning in the R6/2 Mouse Model of Huntington's Disease.

McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M.

PLoS One. 2016 Aug 3;11(8):e0159870. doi: 10.1371/journal.pone.0159870. eCollection 2016.

15.

Brain injury following cardiac arrest: pathophysiology for neurocritical care.

Uchino H, Ogihara Y, Fukui H, Chijiiwa M, Sekine S, Hara N, Elmér E.

J Intensive Care. 2016 Apr 27;4:31. doi: 10.1186/s40560-016-0140-9. eCollection 2016. Review. Retraction in: Uchino H, Ogihara Y, Fukui H, Chijiiwa M, Sekine S, Hara N, Elmér E. J Intensive Care. 2016;4:61.

16.

Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients.

Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E.

Mov Disord Clin Pract. 2016 Feb 11;3(5):472-482. doi: 10.1002/mdc3.12308. eCollection 2016 Sep-Oct.

17.

Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury.

Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS.

Mitochondrion. 2016 Jan;26:19-25. doi: 10.1016/j.mito.2015.11.001. Epub 2015 Nov 5.

18.

DIVERSE AND TISSUE-SPECIFIC MITOCHONDRIAL RESPIRATORY RESPONSE IN A MOUSE MODEL OF SEPSIS-INDUCED MULTIPLE ORGAN FAILURE.

Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E.

Shock. 2016 Apr;45(4):404-10. doi: 10.1097/SHK.0000000000000525.

PMID:
26536202
19.

Metabolomic Analyses of Brain Tissue in Sepsis Induced by Cecal Ligation Reveal Specific Redox Alterations--Protective Effects of the Oxygen Radical Scavenger Edaravone.

Hara N, Chijiiwa M, Yara M, Ishida Y, Ogiwara Y, Inazu M, Kuroda M, Karlsson M, Sjovall F, Elmér E, Uchino H.

Shock. 2015 Dec;44(6):578-84. doi: 10.1097/SHK.0000000000000465.

PMID:
26529662
20.

Cyclosporine before PCI in Patients with Acute Myocardial Infarction.

Cung TT, Morel O, Cayla G, Rioufol G, Garcia-Dorado D, Angoulvant D, Bonnefoy-Cudraz E, Guérin P, Elbaz M, Delarche N, Coste P, Vanzetto G, Metge M, Aupetit JF, Jouve B, Motreff P, Tron C, Labeque JN, Steg PG, Cottin Y, Range G, Clerc J, Claeys MJ, Coussement P, Prunier F, Moulin F, Roth O, Belle L, Dubois P, Barragan P, Gilard M, Piot C, Colin P, De Poli F, Morice MC, Ider O, Dubois-Randé JL, Unterseeh T, Le Breton H, Béard T, Blanchard D, Grollier G, Malquarti V, Staat P, Sudre A, Elmer E, Hansson MJ, Bergerot C, Boussaha I, Jossan C, Derumeaux G, Mewton N, Ovize M.

N Engl J Med. 2015 Sep 10;373(11):1021-31. doi: 10.1056/NEJMoa1505489. Epub 2015 Aug 30.

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