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Items: 1 to 20 of 204

1.

HAI Peptide and Backbone Analogs-Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles.

Arranz-Gibert P, Prades R, Guixer B, Guerrero S, Araya E, Ciudad S, Kogan MJ, Giralt E, Teixidó M.

Sci Rep. 2018 Dec 18;8(1):17932. doi: 10.1038/s41598-018-35938-8.

2.

Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood-brain barrier transport.

Díaz-Perlas C, Oller-Salvia B, Sánchez-Navarro M, Teixidó M, Giralt E.

Chem Sci. 2018 Sep 18;9(44):8409-8415. doi: 10.1039/c8sc02415d. eCollection 2018 Nov 28.

3.

Targeted Nanoswitchable Inhibitors of Protein-Protein Interactions Involved in Apoptosis.

Nevola L, Varese M, Martín-Quirós A, Mari G, Eckelt K, Gorostiza P, Giralt E.

ChemMedChem. 2019 Jan 8;14(1):100-106. doi: 10.1002/cmdc.201800647. Epub 2018 Dec 10.

PMID:
30380184
4.

From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom.

Díaz-Perlas C, Varese M, Guardiola S, García J, Sánchez-Navarro M, Giralt E, Teixidó M.

Chem Commun (Camb). 2018 Nov 8;54(90):12738-12741. doi: 10.1039/c8cc06725b.

PMID:
30357254
5.

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.

Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24.

PMID:
30249646
6.

Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.

Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.

J Antimicrob Chemother. 2018 Dec 1;73(12):3405-3412. doi: 10.1093/jac/dky343.

PMID:
30188994
7.

Blocking EGFR Activation with Anti-EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms.

Guardiola S, Varese M, Sánchez-Navarro M, Vincke C, Teixidó M, García J, Muyldermans S, Giralt E.

Angew Chem Int Ed Engl. 2018 Oct 15;57(42):13843-13847. doi: 10.1002/anie.201807736. Epub 2018 Sep 21.

PMID:
30152597
8.

d-Polyarginine Lipopeptides as Intestinal Permeation Enhancers.

Garcia J, Fernández-Blanco Á, Teixidó M, Sánchez-Navarro M, Giralt E.

ChemMedChem. 2018 Oct 8;13(19):2045-2052. doi: 10.1002/cmdc.201800428. Epub 2018 Aug 20.

PMID:
30063113
9.

Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics.

Guardiola S, Prades R, Mendieta L, Brouwer AJ, Streefkerk J, Nevola L, Tarragó T, Liskamp RMJ, Giralt E.

Cell Chem Biol. 2018 Aug 16;25(8):1031-1037.e4. doi: 10.1016/j.chembiol.2018.04.013. Epub 2018 May 17.

PMID:
29779956
10.

Immunosilencing peptides by stereochemical inversion and sequence reversal: retro-D-peptides.

Arranz-Gibert P, Ciudad S, Seco J, García J, Giralt E, Teixidó M.

Sci Rep. 2018 Apr 24;8(1):6446. doi: 10.1038/s41598-018-24517-6.

11.

Bromotryptophans and their incorporation in cyclic and bicyclic privileged peptides.

García-Pindado J, Willemse T, Goss R, Maes BUW, Giralt E, Ballet S, Teixidó M.

Biopolymers. 2018 Aug;109(10):e23112. doi: 10.1002/bip.23112. Epub 2018 Mar 12.

PMID:
29528113
12.

PEG-PGA enveloped octaarginine-peptide nanocomplexes: An oral peptide delivery strategy.

Niu Z, Samaridou E, Jaumain E, Coëne J, Ullio G, Shrestha N, Garcia J, Durán-Lobato M, Tovar S, Santander-Ortega MJ, Lozano MV, Arroyo-Jimenez MM, Ramos-Membrive R, Peñuelas I, Mabondzo A, Préat V, Teixidó M, Giralt E, Alonso MJ.

J Control Release. 2018 Apr 28;276:125-139. doi: 10.1016/j.jconrel.2018.03.004. Epub 2018 Mar 6.

PMID:
29518466
13.

Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach.

McCully M, Sanchez-Navarro M, Teixido M, Giralt E.

Curr Pharm Des. 2018;24(13):1366-1376. doi: 10.2174/1381612824666171201115126.

14.

Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity.

Kalafatovic D, Giralt E.

Molecules. 2017 Nov 8;22(11). pii: E1929. doi: 10.3390/molecules22111929. Review.

15.

Toward a Novel Drug To Target the EGF-EGFR Interaction: Design of Metabolically Stable Bicyclic Peptides.

Guardiola S, Seco J, Varese M, Díaz-Lobo M, García J, Teixidó M, Nevola L, Giralt E.

Chembiochem. 2018 Jan 4;19(1):76-84. doi: 10.1002/cbic.201700519. Epub 2017 Nov 29.

PMID:
29105934
16.

Combating virulence of Gram-negative bacilli by OmpA inhibition.

Vila-Farrés X, Parra-Millán R, Sánchez-Encinales V, Varese M, Ayerbe-Algaba R, Bayó N, Guardiola S, Pachón-Ibáñez ME, Kotev M, García J, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.

Sci Rep. 2017 Oct 31;7(1):14683. doi: 10.1038/s41598-017-14972-y.

17.

Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2.

Velasco-Aguirre C, Morales-Zavala F, Salas-Huenuleo E, Gallardo-Toledo E, Andonie O, Muñoz L, Rojas X, Acosta G, Sánchez-Navarro M, Giralt E, Araya E, Albericio F, Kogan MJ.

Nanomedicine (Lond). 2017 Oct;12(20):2503-2517. doi: 10.2217/nnm-2017-0181. Epub 2017 Sep 8.

PMID:
28882086
18.

Cytosolic delivery: Just passing through.

Sánchez-Navarro M, Teixidó M, Giralt E.

Nat Chem. 2017 Jul 25;9(8):727-728. doi: 10.1038/nchem.2837. No abstract available.

PMID:
28754938
19.

Jumping Hurdles: Peptides Able To Overcome Biological Barriers.

Sánchez-Navarro M, Teixidó M, Giralt E.

Acc Chem Res. 2017 Aug 15;50(8):1847-1854. doi: 10.1021/acs.accounts.7b00204. Epub 2017 Jul 17.

PMID:
28715199
20.

Peptide multifunctionalized gold nanorods decrease toxicity of β-amyloid peptide in a Caenorhabditis elegans model of Alzheimer's disease.

Morales-Zavala F, Arriagada H, Hassan N, Velasco C, Riveros A, Álvarez AR, Minniti AN, Rojas-Silva X, Muñoz LL, Vasquez R, Rodriguez K, Sanchez-Navarro M, Giralt E, Araya E, Aldunate R, Kogan MJ.

Nanomedicine. 2017 Oct;13(7):2341-2350. doi: 10.1016/j.nano.2017.06.013. Epub 2017 Jun 30.

PMID:
28673851

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