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S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.

Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB.

Cancer Res. 2019 Nov 15;79(22):5758-5768. doi: 10.1158/0008-5472.CAN-19-1366. Epub 2019 Oct 4.


Genomics and molecular mechanisms of high grade serous ovarian cancer: the 12th Biennial Rivkin Center Ovarian Cancer Research Symposium.

Rankin EB.

Int J Gynecol Cancer. 2019 Aug;29(Suppl 2):s7-s11. doi: 10.1136/ijgc-2019-000490.


Hypoxia-Induced Phenotypes that Mediate Tumor Heterogeneity.

Qian J, Rankin EB.

Adv Exp Med Biol. 2019;1136:43-55. doi: 10.1007/978-3-030-12734-3_3. Review.


Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.

Natarajan S, Foreman KM, Soriano MI, Rossen NS, Shehade H, Fregoso DR, Eggold JT, Krishnan V, Dorigo O, Krieg AJ, Heilshorn SC, Sinha S, Fuh KC, Rankin EB.

Cancer Res. 2019 May 1;79(9):2271-2284. doi: 10.1158/0008-5472.CAN-18-2616. Epub 2019 Mar 12.


Erythropoiesis, EPO, macrophages, and bone.

Eggold JT, Rankin EB.

Bone. 2019 Feb;119:36-41. doi: 10.1016/j.bone.2018.03.014. Epub 2018 Mar 15. Review.


Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells.

Wu PH, Onodera Y, Ichikawa Y, Rankin EB, Giaccia AJ, Watanabe Y, Qian W, Hashimoto T, Shirato H, Nam JM.

Int J Nanomedicine. 2017 Jul 14;12:5069-5085. doi: 10.2147/IJN.S137833. eCollection 2017.


Hypoxia: Signaling the Metastatic Cascade.

Rankin EB, Nam JM, Giaccia AJ.

Trends Cancer. 2016 Jun;2(6):295-304. doi: 10.1016/j.trecan.2016.05.006. Epub 2016 Jun 2. Review.


Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data.

Sinha S, Thomas D, Chan S, Gao Y, Brunen D, Torabi D, Reinisch A, Hernandez D, Chan A, Rankin EB, Bernards R, Majeti R, Dill DL.

Nat Commun. 2017 May 31;8:15580. doi: 10.1038/ncomms15580.


Reprogramming the immunological microenvironment through radiation and targeting Axl.

Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ.

Nat Commun. 2016 Dec 23;7:13898. doi: 10.1038/ncomms13898.


Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.

Kariolis MS, Miao YR, Diep A, Nash SE, Olcina MM, Jiang D, Jones DS 2nd, Kapur S, Mathews II, Koong AC, Rankin EB, Cochran JR, Giaccia AJ.

J Clin Invest. 2017 Jan 3;127(1):183-198. doi: 10.1172/JCI85610. Epub 2016 Nov 28.


The Receptor Tyrosine Kinase AXL in Cancer Progression.

Rankin EB, Giaccia AJ.

Cancers (Basel). 2016 Nov 9;8(11). pii: E103. Review.


AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.

Divine LM, Nguyen MR, Meller E, Desai RA, Arif B, Rankin EB, Bligard KH, Meyerson C, Hagemann IS, Massad M, Thaker PH, Hagemann AR, McCourt CK, Powell MA, Mutch DG, Fuh KC.

Oncotarget. 2016 Nov 22;7(47):77291-77305. doi: 10.18632/oncotarget.12637.


Cabozantinib inhibits tumor growth and metastasis of a patient-derived xenograft model of papillary renal cell carcinoma with MET mutation.

Zhao H, Nolley R, Chan AMW, Rankin EB, Peehl DM.

Cancer Biol Ther. 2017 Nov 2;18(11):863-871. doi: 10.1080/15384047.2016.1219816. Epub 2016 Aug 11.


Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling.

Mirzamohammadi F, Papaioannou G, Inloes JB, Rankin EB, Xie H, Schipani E, Orkin SH, Kobayashi T.

Nat Commun. 2016 Jun 22;7:12047. doi: 10.1038/ncomms12047.


Hypoxic control of metastasis.

Rankin EB, Giaccia AJ.

Science. 2016 Apr 8;352(6282):175-80. doi: 10.1126/science.aaf4405. Epub 2016 Apr 7. Review.


Biology of the bone marrow microenvironment and myelodysplastic syndromes.

Rankin EB, Narla A, Park JK, Lin S, Sakamoto KM.

Mol Genet Metab. 2015 Sep-Oct;116(1-2):24-8. doi: 10.1016/j.ymgme.2015.07.004. Epub 2015 Jul 20. Review.


Corrigendum: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.

Wu C, Rankin EB, Castellini L, Alcudia JF, LaGory EL, Andersen R, Rhodes SD, Wilson TL, Mohammad KS, Castillo AB, Guise TA, Schipani E, Giaccia AJ.

Genes Dev. 2015 Jun 1;29(11):1202. No abstract available.


Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.

Wu C, Rankin EB, Castellini L, Alcudia JF, LaGory EL, Andersen R, Rhodes SD, Wilson TL, Mohammad KS, Castillo AB, Guise TA, Schipani E, Giaccia AJ.

Genes Dev. 2015 Apr 15;29(8):817-31. doi: 10.1101/gad.255000.114. Epub 2015 Apr 6. Erratum in: Genes Dev. 2015 Jun 1;29(11):1202. Fernandez-Alcudia, Javier [corrected to Alcudia, Javier F].


Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.

Finger EC, Castellini L, Rankin EB, Vilalta M, Krieg AJ, Jiang D, Banh A, Zundel W, Powell MB, Giaccia AJ.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4441-6. doi: 10.1073/pnas.1418164112. Epub 2015 Mar 19.


Osteoblasts: a novel source of erythropoietin.

Wu C, Giaccia AJ, Rankin EB.

Curr Osteoporos Rep. 2014 Dec;12(4):428-32. doi: 10.1007/s11914-014-0236-x. Review.

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