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Items: 1 to 20 of 48


mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer.

Liang SQ, Bührer ED, Berezowska S, Marti TM, Xu D, Froment L, Yang H, Hall SRR, Vassella E, Yang Z, Kocher GJ, Amrein MA, Riether C, Ochsenbein AF, Schmid RA, Peng RW.

Oncogene. 2019 Jan;38(5):622-636. doi: 10.1038/s41388-018-0479-6. Epub 2018 Aug 31.


Tumor Necrosis Factor-α Initiates miRNA-mRNA Signaling Cascades in Obstruction-Induced Bladder Dysfunction.

Koeck I, Hashemi Gheinani A, Baumgartner U, Vassella E, Bruggmann R, Burkhard FC, Monastyrskaya K.

Am J Pathol. 2018 Aug;188(8):1847-1864. doi: 10.1016/j.ajpath.2018.05.008. Epub 2018 Jun 18.


Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.

Zhong Q, Wagner U, Kurt H, Molinari F, Cathomas G, Komminoth P, Barman-Aksözen J, Schneider-Yin X, Rey JP, Vassella E, Rogel U, Diebold J, McKee T, Jochum W, Kashofer K, Hofman P, Zischka M, Moch H, Rechsteiner M, Wild PJ.

Pathol Res Pract. 2018 Jul;214(7):957-963. doi: 10.1016/j.prp.2018.05.020. Epub 2018 May 22.


Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance.

Wartenberg M, Cibin S, Zlobec I, Vassella E, Eppenberger-Castori S, Terracciano L, Eichmann MD, Worni M, Gloor B, Perren A, Karamitopoulou E.

Clin Cancer Res. 2018 Sep 15;24(18):4444-4454. doi: 10.1158/1078-0432.CCR-17-3401. Epub 2018 Apr 16.


Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery.

Gheinani AH, Vögeli M, Baumgartner U, Vassella E, Draeger A, Burkhard FC, Monastyrskaya K.

Sci Rep. 2018 Mar 2;8(1):3945. doi: 10.1038/s41598-018-22142-x.


miR-19b enhances proliferation and apoptosis resistance via the EGFR signaling pathway by targeting PP2A and BIM in non-small cell lung cancer.

Baumgartner U, Berger F, Hashemi Gheinani A, Burgener SS, Monastyrskaya K, Vassella E.

Mol Cancer. 2018 Feb 19;17(1):44. doi: 10.1186/s12943-018-0781-5.


Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome.

Amer W, Toth C, Vassella E, Meinrath J, Koitzsch U, Arens A, Huang J, Eischeid H, Adam A, Buettner R, Scheel A, Schaefer SC, Odenthal M.

Sci Rep. 2017 Sep 11;7(1):11069. doi: 10.1038/s41598-017-11345-3.


Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting.

Hewer E, Prebil N, Berezowska S, Gutt-Will M, Schucht P, Dettmer MS, Vassella E.

Virchows Arch. 2017 Nov;471(5):641-649. doi: 10.1007/s00428-017-2216-x. Epub 2017 Aug 19.


Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type.

Sartori E, Langer R, Vassella E, Hewer E, Schucht P, Zlobec I, Berezowska S.

Oncol Rep. 2017 Oct;38(4):2394-2400. doi: 10.3892/or.2017.5863. Epub 2017 Aug 1.


Exosomes and Exosomal MicroRNAs in Prostate Cancer Radiation Therapy.

Malla B, Zaugg K, Vassella E, Aebersold DM, Dal Pra A.

Int J Radiat Oncol Biol Phys. 2017 Aug 1;98(5):982-995. doi: 10.1016/j.ijrobp.2017.03.031. Epub 2017 Mar 27. Review.


MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer.

Karamitopoulou E, Haemmig S, Baumgartner U, Schlup C, Wartenberg M, Vassella E.

Mod Pathol. 2017 Aug;30(8):1116-1125. doi: 10.1038/modpathol.2017.35. Epub 2017 May 26.


Intestinal differentiated mucinous adenocarcinoma of the endometrium with sporadic MSI high status: a case report.

Trippel M, Imboden S, Papadia A, Mueller MD, Mertineit N, Härmä K, Nicolae A, Vassella E, Rau TT.

Diagn Pathol. 2017 May 12;12(1):39. doi: 10.1186/s13000-017-0629-0.


PTEN alterations of the stromal cells characterise an aggressive subpopulation of pancreatic cancer with enhanced metastatic potential.

Wartenberg M, Centeno I, Haemmig S, Vassella E, Zlobec I, Galván JA, Neuenschwander M, Schlup C, Gloor B, Lugli A, Perren A, Karamitopoulou E.

Eur J Cancer. 2016 Sep;65:80-90. doi: 10.1016/j.ejca.2016.06.013. Epub 2016 Jul 29.


miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.

Langsch S, Baumgartner U, Haemmig S, Schlup C, Schäfer SC, Berezowska S, Rieger G, Dorn P, Tschan MP, Vassella E.

Cancer Res. 2016 Jul 15;76(14):4160-9. doi: 10.1158/0008-5472.CAN-15-2580. Epub 2016 May 19. Erratum in: Cancer Res. 2016 Nov 1;76(21):6436.


Molecular profiling of lung adenosquamous carcinoma: hybrid or genuine type?

Vassella E, Langsch S, Dettmer MS, Schlup C, Neuenschwander M, Frattini M, Gugger M, Schäfer SC.

Oncotarget. 2015 Sep 15;6(27):23905-16.


Combined ATRX/IDH1 immunohistochemistry predicts genotype of oligoastrocytomas.

Hewer E, Vajtai I, Dettmer MS, Berezowska S, Vassella E.

Histopathology. 2016 Jan;68(2):272-8. doi: 10.1111/his.12743. Epub 2015 Jul 27.


Tissue Microarray Technology for Molecular Applications: Investigation of Cross-Contamination between Tissue Samples Obtained from the Same Punching Device.

Vassella E, Galván JA, Zlobec I.

Microarrays (Basel). 2015 Apr 2;4(2):188-95. doi: 10.3390/microarrays4020188.


Prognostic and predictive roles of MGMT protein expression and promoter methylation in sporadic pancreatic neuroendocrine neoplasms.

Schmitt AM, Pavel M, Rudolph T, Dawson H, Blank A, Komminoth P, Vassella E, Perren A.

Neuroendocrinology. 2014;100(1):35-44. doi: 10.1159/000365514. Epub 2014 Jul 5.


Polymorphous oligodendroglioma of Zülch revisited: a genetically heterogeneous group of anaplastic gliomas including tumors of bona fide oligodendroglial differentiation.

Hewer E, Beck J, Murek M, Kappeler A, Vassella E, Vajtai I.

Neuropathology. 2014 Aug;34(4):323-32. doi: 10.1111/neup.12097. Epub 2014 Jan 21.


Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.

Marinoni I, Kurrer AS, Vassella E, Dettmer M, Rudolph T, Banz V, Hunger F, Pasquinelli S, Speel EJ, Perren A.

Gastroenterology. 2014 Feb;146(2):453-60.e5. doi: 10.1053/j.gastro.2013.10.020. Epub 2013 Oct 19.


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