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Items: 1 to 20 of 75

1.

Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector.

Ellert-Miklaszewska A, Ochocka N, Maleszewska M, Ding L, Laurini E, Jiang Y, Roura AJ, Giorgio S, Gielniewski B, Pricl S, Peng L, Kaminska B.

Nanomedicine (Lond). 2019 Aug 28. doi: 10.2217/nnm-2019-0176. [Epub ahead of print]

PMID:
31456476
2.

Unchain My Blood: Lessons Learned from Self-Assembled Dendrimers as Nanoscale Heparin Binders.

Marson D, Laurini E, Aulic S, Fermeglia M, Pricl S.

Biomolecules. 2019 Aug 20;9(8). pii: E385. doi: 10.3390/biom9080385. Review.

3.

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled In Silico-Experimental Studies. Part I: Covalent siRNA Nanocarriers.

Marson D, Laurini E, Aulic S, Fermeglia M, Pricl S.

Pharmaceutics. 2019 Jul 18;11(7). pii: E351. doi: 10.3390/pharmaceutics11070351. Review.

4.

Evolution from Covalent to Self-Assembled PAMAM-Based Dendrimers as Nanovectors for siRNA Delivery in Cancer by Coupled in Silico-Experimental Studies. Part II: Self-Assembled siRNA Nanocarriers.

Laurini E, Marson D, Aulic S, Fermeglia M, Pricl S.

Pharmaceutics. 2019 Jul 10;11(7). pii: E324. doi: 10.3390/pharmaceutics11070324. Review.

5.

Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum.

Tena-Solsona M, Marson D, Rodrigo AC, Bromfield SM, Escuder B, Miravet JF, Apostolova N, Laurini E, Pricl S, Smith DK.

Biomater Sci. 2019 Aug 20;7(9):3812-3820. doi: 10.1039/c9bm00745h.

PMID:
31264671
6.

Dichloro-Phenyl-Benzotriazoles: A New Selective Class of Human Respiratory Syncytial Virus Entry Inhibitors.

Piras S, Sanna G, Carta A, Corona P, Ibba R, Loddo R, Madeddu S, Caria P, Aulic S, Laurini E, Fermeglia M, Pricl S.

Front Chem. 2019 Apr 16;7:247. doi: 10.3389/fchem.2019.00247. eCollection 2019.

7.

Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes.

Stassi S, Marini M, Allione M, Lopatin S, Marson D, Laurini E, Pricl S, Pirri CF, Ricciardi C, Di Fabrizio E.

Nat Commun. 2019 Apr 12;10(1):1690. doi: 10.1038/s41467-019-09612-0.

8.

Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety.

Kronenberg E, Weber F, Brune S, Schepmann D, Almansa C, Friedland K, Laurini E, Pricl S, Wünsch B.

J Med Chem. 2019 Apr 25;62(8):4204-4217. doi: 10.1021/acs.jmedchem.9b00449. Epub 2019 Apr 12.

PMID:
30939014
9.

Imidazole and 1,2,4-Triazole-based Derivatives Gifted with Antitubercular Activity: Cytotoxicity and Computational Assessment.

Zampieri D, Cateni F, Moneghini M, Zacchigna M, Laurini E, Marson D, De Logu A, Sanna A, Mamolo MG.

Curr Top Med Chem. 2019;19(8):620-632. doi: 10.2174/1568026619666190227183826.

PMID:
30827247
10.

Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase.

Carta A, Bua A, Corona P, Piras S, Briguglio I, Molicotti P, Zanetti S, Laurini E, Aulic S, Fermeglia M, Pricl S.

Eur J Med Chem. 2019 Jan 1;161:399-415. doi: 10.1016/j.ejmech.2018.10.031. Epub 2018 Oct 17.

PMID:
30384044
11.

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors.

Garrigue P, Tang J, Ding L, Bouhlel A, Tintaru A, Laurini E, Huang Y, Lyu Z, Zhang M, Fernandez S, Balasse L, Lan W, Mas E, Marson D, Weng Y, Liu X, Giorgio S, Iovanna J, Pricl S, Guillet B, Peng L.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11454-11459. doi: 10.1073/pnas.1812938115. Epub 2018 Oct 22.

12.

A Dual Targeting Dendrimer-Mediated siRNA Delivery System for Effective Gene Silencing in Cancer Therapy.

Dong Y, Yu T, Ding L, Laurini E, Huang Y, Zhang M, Weng Y, Lin S, Chen P, Marson D, Jiang Y, Giorgio S, Pricl S, Liu X, Rocchi P, Peng L.

J Am Chem Soc. 2018 Nov 28;140(47):16264-16274. doi: 10.1021/jacs.8b10021. Epub 2018 Nov 1.

PMID:
30346764
13.

Self-Assembled Nanomicelles as Curcumin Drug Delivery Vehicles: Impact on Solitary Fibrous Tumor Cell Protein Expression and Viability.

Dagrada G, Rupel K, Zacchigna S, Tamborini E, Pilotti S, Cavalleri A, Fechner LE, Laurini E, Smith DK, Brich S, Pricl S.

Mol Pharm. 2018 Oct 1;15(10):4689-4701. doi: 10.1021/acs.molpharmaceut.8b00655. Epub 2018 Sep 17.

PMID:
30179512
14.

Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.

Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI.

Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11.

PMID:
30025348
15.

Correction: Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment.

Ziouziou H, Andrieu C, Laurini E, Karaki S, Fermeglia M, Oueslati R, Taieb D, Camplo M, Siri O, Pricl S, Katsogiannou M, Rocchi P.

Oncotarget. 2018 Jun 19;9(47):28797. doi: 10.18632/oncotarget.25683. eCollection 2018 Jun 19.

16.

Enantiomeric and Diastereomeric Self-Assembled Multivalent Nanostructures: Understanding the Effects of Chirality on Binding to Polyanionic Heparin and DNA.

Thornalley KA, Laurini E, Pricl S, Smith DK.

Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8530-8534. doi: 10.1002/anie.201803298. Epub 2018 Jun 12.

PMID:
29761907
17.

Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins.

Laurini E, Martinelli V, Lanzicher T, Puzzi L, Borin D, Chen SN, Long CS, Lee P, Mestroni L, Taylor MRG, Sbaizero O, Pricl S.

Cardiovasc Res. 2018 May 1;114(6):846-857. doi: 10.1093/cvr/cvy040.

18.

Quinoxaline derivatives as new inhibitors of coxsackievirus B5.

Carta A, Sanna G, Briguglio I, Madeddu S, Vitale G, Piras S, Corona P, Peana AT, Laurini E, Fermeglia M, Pricl S, Serra A, Carta E, Loddo R, Giliberti G.

Eur J Med Chem. 2018 Feb 10;145:559-569. doi: 10.1016/j.ejmech.2017.12.083. Epub 2017 Dec 27.

PMID:
29339251
19.

9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp).

Loddo R, Francesconi V, Laurini E, Boccardo S, Aulic S, Fermeglia M, Pricl S, Tonelli M.

Bioorg Med Chem. 2018 Feb 15;26(4):855-868. doi: 10.1016/j.bmc.2018.01.001. Epub 2018 Jan 4.

PMID:
29325885
20.

Targeting Hsp27/eIF4E interaction with phenazine compound: a promising alternative for castration-resistant prostate cancer treatment.

Ziouziou H, Andrieu C, Laurini E, Karaki S, Fermeglia M, Oueslati R, Taieb D, Camplo M, Siri O, Pricl S, Katsogiannou M, Rocchi P.

Oncotarget. 2017 Aug 24;8(44):77317-77329. doi: 10.18632/oncotarget.20469. eCollection 2017 Sep 29. Erratum in: Oncotarget. 2018 Jun 19;9(47):28797.

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