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Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling.

Bi J, Thiel KW, Litman JM, Zhang Y, Devor EJ, Newtson AM, Schnieders MJ, Gonzalez Bosquet J, Leslie KK.

Clin Obstet Gynecol. 2020 Mar;63(1):109-119. doi: 10.1097/GRF.0000000000000516.


Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice.

Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL.

Hypertension. 2020 Feb;75(2):569-579. doi: 10.1161/HYPERTENSIONAHA.119.14056. Epub 2019 Dec 23.


Prediction of Epithelial Ovarian Cancer Outcomes With Integration of Genomic Data.

Newtson AM, Devor EJ, Gonzalez Bosquet J.

Clin Obstet Gynecol. 2020 Mar;63(1):92-108. doi: 10.1097/GRF.0000000000000493.


Differential DNA methylation in high-grade serous ovarian cancer (HGSOC) is associated with tumor behavior.

Reyes HD, Devor EJ, Warrier A, Newtson AM, Mattson J, Wagner V, Duncan GN, Leslie KK, Gonzalez-Bosquet J.

Sci Rep. 2019 Nov 29;9(1):17996. doi: 10.1038/s41598-019-54401-w.


Integration of Clinical and Molecular Features into Prediction Models for Outcomes in Endometrial Cancer.

Miller MD, Devor EJ.

Clin Obstet Gynecol. 2020 Mar;63(1):40-47. doi: 10.1097/GRF.0000000000000498.


An integrated prediction model of recurrence in endometrial endometrioid cancers.

Miller MD, Salinas EA, Newtson AM, Sharma D, Keeney ME, Warrier A, Smith BJ, Bender DP, Goodheart MJ, Thiel KW, Devor EJ, Leslie KK, Gonzalez-Bosquet J.

Cancer Manag Res. 2019 Jun 6;11:5301-5315. doi: 10.2147/CMAR.S202628. eCollection 2019.


Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer.

McDonald ME, Salinas EA, Devor EJ, Newtson AM, Thiel KW, Goodheart MJ, Bender DP, Smith BJ, Leslie KK, Gonzalez-Bosquet J.

Int J Mol Sci. 2019 Mar 7;20(5). pii: E1175. doi: 10.3390/ijms20051175.


A Prediction Model for Preoperative Risk Assessment in Endometrial Cancer Utilizing Clinical and Molecular Variables.

Salinas EA, Miller MD, Newtson AM, Sharma D, McDonald ME, Keeney ME, Smith BJ, Bender DP, Goodheart MJ, Thiel KW, Devor EJ, Leslie KK, Gonzalez Bosquet J.

Int J Mol Sci. 2019 Mar 9;20(5). pii: E1205. doi: 10.3390/ijms20051205.


Population Substructure Has Implications in Validating Next-Generation Cancer Genomics Studies with TCGA.

Miller MD, Devor EJ, Salinas EA, Newtson AM, Goodheart MJ, Leslie KK, Gonzalez-Bosquet J.

Int J Mol Sci. 2019 Mar 8;20(5). pii: E1192. doi: 10.3390/ijms20051192.


Trimester-specific plasma exosome microRNA expression profiles in preeclampsia.

Devor E, Santillan D, Scroggins S, Warrier A, Santillan M.

J Matern Fetal Neonatal Med. 2019 Jan 30:1-9. doi: 10.1080/14767058.2019.1569614. [Epub ahead of print]


Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations.

Meng X, Yang S, Li Y, Li Y, Devor EJ, Bi J, Wang X, Umesalma S, Quelle DE, Thiel WH, Thiel KW, Leslie KK.

Dis Markers. 2018 Dec 17;2018:3810108. doi: 10.1155/2018/3810108. eCollection 2018.


Current Landscape and the Potential Role of Hypoxia-Inducible Factors and Selenium in Clear Cell Renal Cell Carcinoma Treatment.

Garje R, An JJ, Sanchez K, Greco A, Stolwijk J, Devor E, Rustum Y, Zakharia Y.

Int J Mol Sci. 2018 Dec 1;19(12). pii: E3834. doi: 10.3390/ijms19123834. Review.


The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes.

Devor EJ, Cha E, Warrier A, Miller MD, Gonzalez-Bosquet J, Leslie KK.

Onco Targets Ther. 2018 Oct 18;11:7205-7211. doi: 10.2147/OTT.S180921. eCollection 2018.


Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics.

Givens BE, Naguib YW, Geary SM, Devor EJ, Salem AK.

AAPS J. 2018 Oct 10;20(6):108. doi: 10.1208/s12248-018-0267-9. Review.


Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia.

Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK.

Clin Sci (Lond). 2018 Feb 14;132(3):419-436. doi: 10.1042/CS20171059. Print 2018 Feb 14.


Dysregulation of miR-181c expression influences recurrence of endometrial endometrioid adenocarcinoma by modulating NOTCH2 expression: An NRG Oncology/Gynecologic Oncology Group study.

Devor EJ, Miecznikowski J, Schickling BM, Gonzalez-Bosquet J, Lankes HA, Thaker P, Argenta PA, Pearl ML, Zweizig SL, Mannel RS, Brown A, Ramirez NC, Ioffe OB, Park KJ, Creasman WT, Birrer MJ, Mutch D, Leslie KK.

Gynecol Oncol. 2017 Dec;147(3):648-653. doi: 10.1016/j.ygyno.2017.09.025. Epub 2017 Sep 29.


High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study.

Reyes HD, Miecznikowski J, Gonzalez-Bosquet J, Devor EJ, Zhang Y, Thiel KW, Samuelson MI, McDonald M, Stephan JM, Hanjani P, Guntupalli S, Tewari KS, Backes F, Ramirez N, Fleming GF, Filiaci V, Birrer MJ, Leslie KK.

Gynecol Oncol. 2017 Aug;146(2):247-253. doi: 10.1016/j.ygyno.2017.05.017. Epub 2017 May 19.


Placenta-Specific Protein 1 Expression in Human Papillomavirus 16/18-Positive Cervical Cancers Is Associated With Tumor Histology.

Devor EJ, Reyes HD, Gonzalez-Bosquet J, Warrier A, Kenzie SA, Ibik NV, Miller MD, Schickling BM, Goodheart MJ, Thiel KW, Leslie KK.

Int J Gynecol Cancer. 2017 May;27(4):784-790. doi: 10.1097/IGC.0000000000000957.


p53 mutation status is a primary determinant of placenta-specific protein 1 expression in serous ovarian cancers.

Devor EJ, Gonzalez-Bosquet J, Warrier A, Reyes HD, Ibik NV, Schickling BM, Newtson A, Goodheart MJ, Leslie KK.

Int J Oncol. 2017 May;50(5):1721-1728. doi: 10.3892/ijo.2017.3931. Epub 2017 Mar 23.


Differentially expressed genes in preimplantation human embryos: potential candidate genes for blastocyst formation and implantation.

Munch EM, Sparks AE, Gonzalez Bosquet J, Christenson LK, Devor EJ, Van Voorhis BJ.

J Assist Reprod Genet. 2016 Aug;33(8):1017-25. doi: 10.1007/s10815-016-0745-x. Epub 2016 May 30.

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