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Items: 1 to 20 of 135

1.

CD90/Thy-1, a Cancer-Associated Cell Surface Signaling Molecule.

Sauzay C, Voutetakis K, Chatziioannou A, Chevet E, Avril T.

Front Cell Dev Biol. 2019 Apr 26;7:66. doi: 10.3389/fcell.2019.00066. eCollection 2019. Review.

2.

Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion.

Limia CM, Sauzay C, Urra H, Hetz C, Chevet E, Avril T.

Cancers (Basel). 2019 May 6;11(5). pii: E631. doi: 10.3390/cancers11050631. Review.

3.

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.

Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E.

EMBO Mol Med. 2019 Jun;11(6). pii: e10120. doi: 10.15252/emmm.201810120.

4.

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.

Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, Chintha C, Schubert T, Samali A, Chevet E, Eriksson LA, Huber M, Tirosh B.

Cell Death Dis. 2019 Apr 1;10(4):300. doi: 10.1038/s41419-019-1523-3.

5.

The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation.

Parzych K, Saavedra-García P, Valbuena GN, Al-Sadah HA, Robinson ME, Penfold L, Kuzeva DM, Ruiz-Tellez A, Loaiza S, Holzmann V, Caputo V, Johnson DC, Kaiser MF, Karadimitris A, Lam EW, Chevet E, Feldhahn N, Keun HC, Auner HW.

Oncogene. 2019 Apr;38(17):3216-3231. doi: 10.1038/s41388-018-0651-z. Epub 2019 Jan 9.

6.

The expression of EMX2 lead to cell cycle arrest in glioblastoma cell line.

Monnier A, Boniface R, Bouvet R, Etcheverry A, Aubry M, Avril T, Quillien V, Chevet E, Mosser J.

BMC Cancer. 2018 Dec 4;18(1):1213. doi: 10.1186/s12885-018-5094-y.

7.

Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.

Obiedat A, Seidel E, Mahameed M, Berhani O, Tsukerman P, Voutetakis K, Chatziioannou A, McMahon M, Avril T, Chevet E, Mandelboim O, Tirosh B.

FASEB J. 2019 Mar;33(3):3481-3495. doi: 10.1096/fj.201801350RR. Epub 2018 Nov 19.

PMID:
30452881
8.

Alterations of EDEM1 functions enhance ATF6 pro-survival signaling.

Papaioannou A, Higa A, Jégou G, Jouan F, Pineau R, Saas L, Avril T, Pluquet O, Chevet E.

FEBS J. 2018 Nov;285(22):4146-4164. doi: 10.1111/febs.14669. Epub 2018 Oct 20.

9.

Should the clinic matter to nonphysician scientists?

Le Reste PJ, Chevet E.

Sci Signal. 2018 Sep 11;11(547). pii: eaau4240. doi: 10.1126/scisignal.aau4240. Review.

PMID:
30206137
10.

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy.

Logue SE, McGrath EP, Cleary P, Greene S, Mnich K, Almanza A, Chevet E, Dwyer RM, Oommen A, Legembre P, Godey F, Madden EC, Leuzzi B, Obacz J, Zeng Q, Patterson JB, Jäger R, Gorman AM, Samali A.

Nat Commun. 2018 Aug 15;9(1):3267. doi: 10.1038/s41467-018-05763-8.

11.

Publisher Correction: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0186-0.

PMID:
30089843
12.

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications.

Almanza A, Carlesso A, Chintha C, Creedican S, Doultsinos D, Leuzzi B, Luís A, McCarthy N, Montibeller L, More S, Papaioannou A, Püschel F, Sassano ML, Skoko J, Agostinis P, de Belleroche J, Eriksson LA, Fulda S, Gorman AM, Healy S, Kozlov A, Muñoz-Pinedo C, Rehm M, Chevet E, Samali A.

FEBS J. 2019 Jan;286(2):241-278. doi: 10.1111/febs.14608. Epub 2018 Aug 4. Review.

13.

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Erratum in: Nat Cell Biol. 2018 Oct;20(10):1228.

PMID:
30013108
14.

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.

Lebeaupin C, Vallée D, Hazari Y, Hetz C, Chevet E, Bailly-Maitre B.

J Hepatol. 2018 Oct;69(4):927-947. doi: 10.1016/j.jhep.2018.06.008. Epub 2018 Jun 27. Review.

15.

Reshaping the Immune Tumor Microenvironment Through IRE1 Signaling.

Rubio-Patiño C, Bossowski JP, Chevet E, Ricci JE.

Trends Mol Med. 2018 Jul;24(7):607-614. doi: 10.1016/j.molmed.2018.05.005. Epub 2018 May 24. Review.

PMID:
29804923
16.

Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.

Rubio-Patiño C, Bossowski JP, De Donatis GM, Mondragón L, Villa E, Aira LE, Chiche J, Mhaidly R, Lebeaupin C, Marchetti S, Voutetakis K, Chatziioannou A, Castelli FA, Lamourette P, Chu-Van E, Fenaille F, Avril T, Passeron T, Patterson JB, Verhoeyen E, Bailly-Maitre B, Chevet E, Ricci JE.

Cell Metab. 2018 Apr 3;27(4):828-842.e7. doi: 10.1016/j.cmet.2018.02.009.

17.

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.

Sepulveda D, Rojas-Rivera D, Rodríguez DA, Groenendyk J, Köhler A, Lebeaupin C, Ito S, Urra H, Carreras-Sureda A, Hazari Y, Vasseur-Cognet M, Ali MMU, Chevet E, Campos G, Godoy P, Vaisar T, Bailly-Maitre B, Nagata K, Michalak M, Sierralta J, Hetz C.

Mol Cell. 2018 Jan 18;69(2):238-252.e7. doi: 10.1016/j.molcel.2017.12.028.

18.

Dual IRE1 RNase functions dictate glioblastoma development.

Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E.

EMBO Mol Med. 2018 Mar;10(3). pii: e7929. doi: 10.15252/emmm.201707929.

19.

Regulation of tumor-stroma interactions by the unfolded protein response.

Obacz J, Avril T, Rubio-Patiño C, Bossowski JP, Igbaria A, Ricci JE, Chevet E.

FEBS J. 2019 Jan;286(2):279-296. doi: 10.1111/febs.14359. Epub 2017 Dec 29. Review.

20.

CD90 Expression Controls Migration and Predicts Dasatinib Response in Glioblastoma.

Avril T, Etcheverry A, Pineau R, Obacz J, Jegou G, Jouan F, Le Reste PJ, Hatami M, Colen RR, Carlson BL, Decker PA, Sarkaria JN, Vauléon E, Chiforeanu DC, Clavreul A, Mosser J, Chevet E, Quillien V.

Clin Cancer Res. 2017 Dec 1;23(23):7360-7374. doi: 10.1158/1078-0432.CCR-17-1549. Epub 2017 Sep 22.

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