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Items: 1 to 20 of 41

1.

Ajothiolanes: 3,4-Dimethylthiolane Natural Products from Garlic ( Allium sativum).

Block E, Dethier B, Bechand B, Cotelesage JJH, George GN, Goto K, Pickering IJ, Mendoza Rengifo E, Sheridan R, Sneeden EY, Vogt L.

J Agric Food Chem. 2018 Sep 19. doi: 10.1021/acs.jafc.8b03638. [Epub ahead of print]

PMID:
30196701
2.

A Multispecific Investigation of the Metal Effect in Mammalian Odorant Receptors for Sulfur-Containing Compounds.

Zhang R, Pan Y, Ahmed L, Block E, Zhang Y, Batista VS, Zhuang H.

Chem Senses. 2018 May 23;43(5):357-366. doi: 10.1093/chemse/bjy022.

PMID:
29659735
3.

Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds.

Ahmed L, Zhang Y, Block E, Buehl M, Corr MJ, Cormanich RA, Gundala S, Matsunami H, O'Hagan D, Ozbil M, Pan Y, Sekharan S, Ten N, Wang M, Yang M, Zhang Q, Zhang R, Batista VS, Zhuang H.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3950-E3958. doi: 10.1073/pnas.1713026115. Epub 2018 Apr 9.

PMID:
29632183
4.

Fluorinated Analog NMR s of Organosulfur Compounds from Garlic (Allium sativum): Synthesis, Chemistry and Anti-Angiogenesis and Antithrombotic Studies.

Block E, Bechand B, Gundala S, Vattekkatte A, Wang K, Mousa SS, Godugu K, Yalcin M, Mousa SA.

Molecules. 2017 Nov 28;22(12). pii: E2081. doi: 10.3390/molecules22122081.

5.

Photochemically Generated Thiyl Free Radicals Observed by X-ray Absorption Spectroscopy.

Sneeden EY, Hackett MJ, Cotelesage JJH, Prince RC, Barney M, Goto K, Block E, Pickering IJ, George GN.

J Am Chem Soc. 2017 Aug 23;139(33):11519-11526. doi: 10.1021/jacs.7b05116. Epub 2017 Aug 11.

PMID:
28750509
6.

The role of metals in mammalian olfaction of low molecular weight organosulfur compounds.

Block E, Batista VS, Matsunami H, Zhuang H, Ahmed L.

Nat Prod Rep. 2017 May 10;34(5):529-557. doi: 10.1039/c7np00016b. Review.

7.

Smelling Sulfur: Copper and Silver Regulate the Response of Human Odorant Receptor OR2T11 to Low-Molecular-Weight Thiols.

Li S, Ahmed L, Zhang R, Pan Y, Matsunami H, Burger JL, Block E, Batista VS, Zhuang H.

J Am Chem Soc. 2016 Oct 3. [Epub ahead of print]

PMID:
27659093
8.

Trifluoroselenomethionine: A New Unnatural Amino Acid.

Block E, Booker SJ, Flores-Penalba S, George GN, Gundala S, Landgraf BJ, Liu J, Lodge SN, Pushie MJ, Rozovsky S, Vattekkatte A, Yaghi R, Zeng H.

Chembiochem. 2016 Sep 15;17(18):1738-51. doi: 10.1002/cbic.201600266. Epub 2016 Sep 7.

9.

Reply to Turin et al.: Vibrational theory of olfaction is implausible.

Block E, Jang S, Matsunami H, Batista VS, Zhuang H.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3155. doi: 10.1073/pnas.1508443112. Epub 2015 Jun 4. No abstract available.

10.

Implausibility of the vibrational theory of olfaction.

Block E, Jang S, Matsunami H, Sekharan S, Dethier B, Ertem MZ, Gundala S, Pan Y, Li S, Li Z, Lodge SN, Ozbil M, Jiang H, Penalba SF, Batista VS, Zhuang H.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2766-74. doi: 10.1073/pnas.1503054112. Epub 2015 Apr 21.

11.

QM/MM model of the mouse olfactory receptor MOR244-3 validated by site-directed mutagenesis experiments.

Sekharan S, Ertem MZ, Zhuang H, Block E, Matsunami H, Zhang R, Wei JN, Pan Y, Batista VS.

Biophys J. 2014 Sep 2;107(5):L5-L8. doi: 10.1016/j.bpj.2014.07.031.

12.

Crucial role of copper in detection of metal-coordinating odorants.

Duan X, Block E, Li Z, Connelly T, Zhang J, Huang Z, Su X, Pan Y, Wu L, Chi Q, Thomas S, Zhang S, Ma M, Matsunami H, Chen GQ, Zhuang H.

Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3492-7. doi: 10.1073/pnas.1111297109. Epub 2012 Feb 10.

13.

Microwave spectra and gas phase structural parameters for N-hydroxypyridine-2(1H)-thione.

Daly AM, Mitchell EG, Sanchez DA, Block E, Kukolich SG.

J Phys Chem A. 2011 Dec 22;115(50):14526-30. doi: 10.1021/jp2080385. Epub 2011 Nov 30.

PMID:
22070758
14.
16.

Electrochemical and chemical oxidation of dithia-, diselena-, ditellura-, selenathia-, and tellurathiamesocycles and stability of the oxidized species.

Evans DH, Gruhn NE, Jin J, Li B, Lorance E, Okumura N, MacĂ­as-Ruvalcaba NA, Zakai UI, Zhang SZ, Block E, Glass RS.

J Org Chem. 2010 Mar 19;75(6):1997-2009. doi: 10.1021/jo9026484.

PMID:
20180528
17.
18.

A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors.

Wang T, Ledeboer MW, Duffy JP, Salituro FG, Pierce AC, Zuccola HJ, Block E, Shlyakter D, Hogan JK, Bennani YL.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):153-6. doi: 10.1016/j.bmcl.2009.11.021. Epub 2009 Nov 12. Erratum in: Bioorg Med Chem Lett. 2010 Apr 15;20(8):2684. Salituro, Francesco G [added].

PMID:
19945871
19.

In vitro and in vivo isotope effects with hepatitis C protease inhibitors: enhanced plasma exposure of deuterated telaprevir versus telaprevir in rats.

Maltais F, Jung YC, Chen M, Tanoury J, Perni RB, Mani N, Laitinen L, Huang H, Liao S, Gao H, Tsao H, Block E, Ma C, Shawgo RS, Town C, Brummel CL, Howe D, Pazhanisamy S, Raybuck S, Namchuk M, Bennani YL.

J Med Chem. 2009 Dec 24;52(24):7993-8001. doi: 10.1021/jm901023f.

PMID:
19894743
20.

Localizing the chemical forms of sulfur in vivo using X-ray fluorescence spectroscopic imaging: application to onion (Allium cepa) tissues.

Pickering IJ, Sneeden EY, Prince RC, Block E, Harris HH, Hirsch G, George GN.

Biochemistry. 2009 Jul 28;48(29):6846-53. doi: 10.1021/bi900368x.

PMID:
19463015

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