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Activity of Estafietin and Analogues on Trypanosoma cruzi and Leishmania braziliensis.

Sülsen VP, Lizarraga EF, Elso OG, Cerny N, Sanchez Alberti A, Bivona AE, Malchiodi EL, Cazorla SI, Catalán CAN.

Molecules. 2019 Mar 28;24(7). pii: E1209. doi: 10.3390/molecules24071209.


Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action.

Beer MF, Bivona AE, Sánchez Alberti A, Cerny N, Reta GF, Martín VS, Padrón JM, Malchiodi EL, Sülsen VP, Donadel OJ.

Molecules. 2019 Mar 20;24(6). pii: E1113. doi: 10.3390/molecules24061113.


Trypanosoma cruzi 80 kDa prolyl oligopeptidase (Tc80) as a novel immunogen for Chagas disease vaccine.

Bivona AE, Sánchez Alberti A, Matos MN, Cerny N, Cardoso AC, Morales C, González G, Cazorla SI, Malchiodi EL.

PLoS Negl Trop Dis. 2018 Mar 30;12(3):e0006384. doi: 10.1371/journal.pntd.0006384. eCollection 2018 Mar.


Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection.

Sanchez Alberti A, Bivona AE, Cerny N, Schulze K, Weißmann S, Ebensen T, Morales C, Padilla AM, Cazorla SI, Tarleton RL, Guzmán CA, Malchiodi EL.

NPJ Vaccines. 2017 Apr 10;2:9. doi: 10.1038/s41541-017-0010-z. eCollection 2017.


Evidence of size-dependent effect of silica micro- and nano-particles on basal and specialized monocyte functions.

De Marzi MC, Saraceno M, Mitarotonda R, Todone M, Fernandez M, Malchiodi EL, Desimone MF.

Ther Deliv. 2017 Dec;8(12):1035-1049. doi: 10.4155/tde-2017-0053.


Assessment of sesquiterpene lactones isolated from Mikania plants species for their potential efficacy against Trypanosoma cruzi and Leishmania sp.

Laurella LC, Cerny N, Bivona AE, Sánchez Alberti A, Giberti G, Malchiodi EL, Martino VS, Catalan CA, Alonso MR, Cazorla SI, Sülsen VP.

PLoS Negl Trop Dis. 2017 Sep 25;11(9):e0005929. doi: 10.1371/journal.pntd.0005929. eCollection 2017 Sep.


Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi.

Matos MN, Cazorla SI, Schulze K, Ebensen T, Guzmán CA, Malchiodi EL.

PLoS Negl Trop Dis. 2017 Feb 24;11(2):e0005300. doi: 10.1371/journal.pntd.0005300. eCollection 2017 Feb.


Kinetic and thermodynamic studies of the interaction between activating and inhibitory Ly49 natural killer receptors and MHC class I molecules.

Romasanta PN, Curto LM, Sarratea MB, Noli Truant S, Antonoglou MB, Fernández Lynch MJ, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

Biochem J. 2017 Jan 1;474(1):179-194. doi: 10.1042/BCJ20160876. Epub 2016 Nov 9.


MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity.

Margara LM, Fernández MM, Malchiodi EL, Argaraña CE, Monti MR.

Nucleic Acids Res. 2016 Sep 19;44(16):7700-13. doi: 10.1093/nar/gkw494. Epub 2016 Jun 1.


A prime-boost immunization with Tc52 N-terminal domain DNA and the recombinant protein expressed in Pichia pastoris protects against Trypanosoma cruzi infection.

Matos MN, Sánchez Alberti A, Morales C, Cazorla SI, Malchiodi EL.

Vaccine. 2016 Jun 14;34(28):3243-51. doi: 10.1016/j.vaccine.2016.05.011. Epub 2016 May 10.


Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells.

Fernández MM, Ferragut F, Cárdenas Delgado VM, Bracalente C, Bravo AI, Cagnoni AJ, Nuñez M, Morosi LG, Quinta HR, Espelt MV, Troncoso MF, Wolfenstein-Todel C, Mariño KV, Malchiodi EL, Rabinovich GA, Elola MT.

Biochim Biophys Acta. 2016 Oct;1860(10):2255-68. doi: 10.1016/j.bbagen.2016.04.019. Epub 2016 Apr 26.


Attenuated Salmonella sp. as a DNA Delivery System for Trypanosoma cruzi Antigens.

Bivona AE, Cerny N, Alberti AS, Cazorla SI, Malchiodi EL.

Methods Mol Biol. 2016;1404:683-95. doi: 10.1007/978-1-4939-3389-1_44.


Coadministration of cruzipain and GM-CSF DNAs, a new immunotherapeutic vaccine against Trypanosoma cruzi infection.

Cerny N, Sánchez Alberti A, Bivona AE, De Marzi MC, Frank FM, Cazorla SI, Malchiodi EL.

Hum Vaccin Immunother. 2016;12(2):438-50. doi: 10.1080/21645515.2015.1078044.


A positive cooperativity binding model between Ly49 natural killer cell receptors and the viral immunoevasin m157. KINETIC AND THERMODYNAMIC STUDIES.

Romasanta PN, Curto LM, Urtasun N, Sarratea MB, Chiappini S, Miranda MV, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

J Biol Chem. 2015 Aug 14;290(33):20098-9. doi: 10.1074/jbc.A113.532929. No abstract available.


Peptidoglycan recognition protein-peptidoglycan complexes increase monocyte/macrophage activation and enhance the inflammatory response.

De Marzi MC, Todone M, Ganem MB, Wang Q, Mariuzza RA, Fernández MM, Malchiodi EL.

Immunology. 2015 Jul;145(3):429-42. doi: 10.1111/imm.12460. Epub 2015 Apr 16.


Oral multicomponent DNA vaccine delivered by attenuated Salmonella elicited immunoprotection against American trypanosomiasis.

Cazorla SI, Matos MN, Cerny N, Ramirez C, Alberti AS, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

J Infect Dis. 2015 Mar 1;211(5):698-707. doi: 10.1093/infdis/jiu480. Epub 2014 Aug 25.


Galectin-3 is essential for early wound healing and ventricular remodeling after myocardial infarction in mice.

González GE, Cassaglia P, Noli Truant S, Fernández MM, Wilensky L, Volberg V, Malchiodi EL, Morales C, Gelpi RJ.

Int J Cardiol. 2014 Oct 20;176(3):1423-5. doi: 10.1016/j.ijcard.2014.08.011. Epub 2014 Aug 8. No abstract available.


Tc52 amino-terminal-domain DNA carried by attenuated Salmonella enterica serovar Typhimurium induces protection against a Trypanosoma cruzi lethal challenge.

Matos MN, Cazorla SI, Bivona AE, Morales C, Guzmán CA, Malchiodi EL.

Infect Immun. 2014 Oct;82(10):4265-75. doi: 10.1128/IAI.02190-14. Epub 2014 Jul 28.


A positive cooperativity binding model between Ly49 natural killer cell receptors and the viral immunoevasin m157: kinetic and thermodynamic studies.

Romasanta PN, Curto LM, Urtasun N, Sarratea MB, Chiappini S, Miranda MV, Delfino JM, Mariuzza RA, Fernández MM, Malchiodi EL.

J Biol Chem. 2014 Feb 21;289(8):5083-96. doi: 10.1074/jbc.M113.532929. Epub 2013 Dec 30. Erratum in: J Biol Chem. 2015 Aug 14;290(33):20098-9.


Novel evidence for the specific interaction between cholesterol and α-haemolysin of Escherichia coli.

Vazquez RF, Maté SM, Bakás LS, Fernández MM, Malchiodi EL, Herlax VS.

Biochem J. 2014 Mar 15;458(3):481-9. doi: 10.1042/BJ20131432.


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