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Items: 9


Development of a Novel Series of Anticancer and Antidiabetic: Spirothiazolidines Analogs.

Flefel EM, El-Sofany WI, Al-Harbi RAK, El-Shahat M.

Molecules. 2019 Jul 9;24(13). pii: E2511. doi: 10.3390/molecules24132511.


Synthesis, Molecular Docking and in Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridineā»Pyrazole Hybrid Derivatives.

Flefel EM, El-Sofany WI, El-Shahat M, Naqvi A, Assirey E.

Molecules. 2018 Oct 6;23(10). pii: E2548. doi: 10.3390/molecules23102548.


Synthesis and Anticancer Activity of New 1-Thia-4-azaspiro[4.5]decane, Their Derived Thiazolopyrimidine and 1,3,4-Thiadiazole Thioglycosides.

Flefel EM, El-Sayed WA, Mohamed AM, El-Sofany WI, Awad HM.

Molecules. 2017 Jan 20;22(1). pii: E170. doi: 10.3390/molecules22010170.


Synthesis of Some New Pyridazine Derivatives for Anti-HAV Evaluation.

Flefel EM, Tantawy WA, El-Sofany WI, El-Shahat M, El-Sayed AA, Abd-Elshafy DN.

Molecules. 2017 Jan 17;22(1). pii: E148. doi: 10.3390/molecules22010148.


Synthesis and Cytotoxic Effect of Some Novel 1,2-Dihydropyridin-3-carbonitrile and Nicotinonitrile Derivatives.

M Flefel E, S Abbas HA, E Abdel Mageid R, A Zaghary W.

Molecules. 2015 Dec 31;21(1):E30. doi: 10.3390/molecules21010030.


Synthesis and pharmacological activities of some new triazolo- and tetrazolopyrimidine derivatives.

Bahashwan SA, Fayed AA, Amr Ael-G, Flefel EM, Kalmouch A.

Molecules. 2013 Dec 6;18(12):15051-63. doi: 10.3390/molecules181215051.


Heterocyclic compounds based on 3-(4-bromophenyl) azo-5-phenyl-2(3H)-furanone: anti-avian influenza virus (H5N1) activity.

Flefel EM, Abdel-Mageid RE, Tantawy WA, Ali MA, Amr Ael-G.

Acta Pharm. 2012 Dec;62(4):593-606. doi: 10.2478/v10007-012-0037-7.


Synthesis of new macrocyclic polyamides as antimicrobial agent candidates.

El-Salam OI, Al-Omar MA, Fayed AA, Flefel EM, Amr Ael-G.

Molecules. 2012 Dec 6;17(12):14510-21. doi: 10.3390/molecules171214510.


Anti-HSV-1 activity and mechanism of action of some new synthesized substituted pyrimidine, thiopyrimidine and thiazolopyrimidine derivatives.

Mohamed SF, Flefel EM, Amr Ael-G, Abd El-Shafy DN.

Eur J Med Chem. 2010 Apr;45(4):1494-501. doi: 10.1016/j.ejmech.2009.12.057. Epub 2010 Jan 13.


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