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Items: 1 to 20 of 70


Disseminated hematogenous tuberculosis in puerperium-case report.

Barbosa OA, Teles FM, Maia ACC, Pessoa GMF, de Alencar IM, de Sousa ET, Jorge Bezerra Simão SD.

Oxf Med Case Reports. 2019 Dec 9;2019(11):479-481. doi: 10.1093/omcr/omz116. eCollection 2019 Nov.


P-glycoprotein activation by 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) in rat distal ileum: ex vivo and in vivo studies.

Rocha-Pereira C, Ghanem CI, Silva R, Casanova AG, Duarte-Araújo M, Gonçalves-Monteiro S, Sousa E, Bastos ML, Remião F.

Toxicol Appl Pharmacol. 2020 Jan 1;386:114832. doi: 10.1016/j.taap.2019.114832. Epub 2019 Nov 19.


Overcoming environmental problems of biocides: Synthetic bile acid derivatives as a sustainable alternative.

Neves AR, Almeida JR, Carvalhal F, Câmara A, Pereira S, Antunes J, Vasconcelos V, Pinto M, Silva ER, Sousa E, Correia-da-Silva M.

Ecotoxicol Environ Saf. 2020 Jan 15;187:109812. doi: 10.1016/j.ecoenv.2019.109812. Epub 2019 Oct 24.


Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5).

Rocha-Pereira C, Silva V, Costa VM, Silva R, Garcia J, Gonçalves-Monteiro S, Duarte-Araújo M, Santos-Silva A, Coimbra S, Dinis-Oliveira RJ, Lopes C, Silva P, Long S, Sousa E, de Lourdes Bastos M, Remião F.

EXCLI J. 2019 Aug 27;18:697-722. doi: 10.17179/excli2019-1675. eCollection 2019.


1,2-Dihydroxyxanthone: Effect on A375-C5 Melanoma Cell Growth Associated with Interference with THP-1 Human Macrophage Activity.

Silva V, Cerqueira F, Nazareth N, Medeiros R, Sarmento A, Sousa E, Pinto M.

Pharmaceuticals (Basel). 2019 Jun 4;12(2). pii: E85. doi: 10.3390/ph12020085.


Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines.

Durães F, Sousa E.

Pharmaceuticals (Basel). 2019 Apr 21;12(2). pii: E63. doi: 10.3390/ph12020063.


BACE-1 and γ-Secretase as Therapeutic Targets for Alzheimer's Disease.

Maia MA, Sousa E.

Pharmaceuticals (Basel). 2019 Mar 19;12(1). pii: E41. doi: 10.3390/ph12010041. Review.


Antithrombotics from the Sea: Polysaccharides and Beyond.

Carvalhal F, Cristelo RR, Resende DISP, Pinto MMM, Sousa E, Correia-da-Silva M.

Mar Drugs. 2019 Mar 16;17(3). pii: E170. doi: 10.3390/md17030170. Review.


The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells.

Reis-Mendes A, Carvalho F, Remião F, Sousa E, Bastos ML, Costa VM.

Biomolecules. 2019 Mar 11;9(3). pii: E98. doi: 10.3390/biom9030098.


Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies.

Martins E, Silva V, Lemos A, Palmeira A, Puthongking P, Sousa E, Rocha-Pereira C, Ghanem CI, Carmo H, Remião F, Silva R.

Molecules. 2019 Feb 15;24(4). pii: E707. doi: 10.3390/molecules24040707.


Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects.

Long S, Resende DISP, Kijjoa A, Silva AMS, Fernandes R, Xavier CPR, Vasconcelos MH, Sousa E, Pinto MMM.

Molecules. 2019 Feb 1;24(3). pii: E534. doi: 10.3390/molecules24030534.


Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations.

Alves A, Correia-da-Silva M, Nunes C, Campos J, Sousa E, Silva PMA, Bousbaa H, Rodrigues F, Ferreira D, Costa PC, Pinto M.

Molecules. 2019 Jan 23;24(3). pii: E409. doi: 10.3390/molecules24030409.


New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.

Gomes S, Raimundo L, Soares J, Loureiro JB, Leão M, Ramos H, Monteiro MN, Lemos A, Moreira J, Pinto M, Chlapek P, Veselska R, Sousa E, Saraiva L.

Cancer Lett. 2019 Apr 1;446:90-102. doi: 10.1016/j.canlet.2019.01.014. Epub 2019 Jan 19.


The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization.

Lima RT, Sousa D, Gomes AS, Mendes N, Matthiesen R, Pedro M, Marques F, Pinto MM, Sousa E, Vasconcelos MH.

Molecules. 2018 Dec 12;23(12). pii: E3301. doi: 10.3390/molecules23123301.


Lichen Xanthones as Models for New Antifungal Agents.

Resende DISP, Pereira-Terra P, Inácio ÂS, Costa PMD, Pinto E, Sousa E, Pinto MMM.

Molecules. 2018 Oct 12;23(10). pii: E2617. doi: 10.3390/molecules23102617.


Chemistry of the fumiquinazolines and structurally related alkaloids.

Resende DISP, Boonpothong P, Sousa E, Kijjoa A, Pinto MMM.

Nat Prod Rep. 2019 Jan 1;36(1):7-34. doi: 10.1039/c8np00043c. Epub 2018 Aug 9. Review.


Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products.

Long S, Resende DISP, Kijjoa A, Silva AMS, Pina A, Fernández-Marcelo T, Vasconcelos MH, Sousa E, Pinto MMM.

Mar Drugs. 2018 Jul 31;16(8). pii: E261. doi: 10.3390/md16080261.


Old Drugs as New Treatments for Neurodegenerative Diseases.

Durães F, Pinto M, Sousa E.

Pharmaceuticals (Basel). 2018 May 11;11(2). pii: E44. doi: 10.3390/ph11020044. Review.


Synthesis of New Glycosylated Flavonoids with Inhibitory Activity on Cell Growth.

Neves AR, Correia-da-Silva M, Silva PMA, Ribeiro D, Sousa E, Bousbaa H, Pinto M.

Molecules. 2018 May 5;23(5). pii: E1093. doi: 10.3390/molecules23051093.


Lipid reducing activity and toxicity profiles of a library of polyphenol derivatives.

Urbatzka R, Freitas S, Palmeira A, Almeida T, Moreira J, Azevedo C, Afonso C, Correia-da-Silva M, Sousa E, Pinto M, Vasconcelos V.

Eur J Med Chem. 2018 May 10;151:272-284. doi: 10.1016/j.ejmech.2018.03.036. Epub 2018 Mar 23.


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