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Items: 1 to 20 of 29


Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB.

Camorani S, Cerchia L, Fedele M, Erba E, D'Incalci M, Crescenzi E.

Oncotarget. 2018 Apr 13;9(28):19929-19944. doi: 10.18632/oncotarget.24961. eCollection 2018 Apr 13.


Oligonucleotide aptamers against tyrosine kinase receptors: Prospect for anticancer applications.

Camorani S, Crescenzi E, Fedele M, Cerchia L.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):263-277. doi: 10.1016/j.bbcan.2018.03.003. Epub 2018 Mar 21. Review.


The POZ/BTB and AT-Hook Containing Zinc Finger 1 (PATZ1) Transcription Regulator: Physiological Functions and Disease Involvement.

Fedele M, Crescenzi E, Cerchia L.

Int J Mol Sci. 2017 Nov 24;18(12). pii: E2524. doi: 10.3390/ijms18122524. Review.


PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype.

Guadagno E, Vitiello M, Francesca P, Calì G, Caponnetto F, Cesselli D, Camorani S, Borrelli G, Califano M, Cappabianca P, Arra C, Crescenzi E, Cerchia L, De Caro MLDB, Fedele M.

Oncotarget. 2017 Jul 25;8(35):59282-59300. doi: 10.18632/oncotarget.19546. eCollection 2017 Aug 29.


ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype.

Miglionico R, Ostuni A, Armentano MF, Milella L, Crescenzi E, Carmosino M, Bisaccia F.

Cell Mol Biol Lett. 2017 Apr 4;22:7. doi: 10.1186/s11658-017-0036-2. eCollection 2017.


Aptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers.

Camorani S, Crescenzi E, Gramanzini M, Fedele M, Zannetti A, Cerchia L.

Sci Rep. 2017 Apr 20;7:46659. doi: 10.1038/srep46659.


PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells.

Vitiello M, Valentino T, De Menna M, Crescenzi E, Francesca P, Rea D, Arra C, Fusco A, De Vita G, Cerchia L, Fedele M.

Sci Rep. 2016 Apr 29;6:25268. doi: 10.1038/srep25268.


Polyphenolic Profile and Targeted Bioactivity of Methanolic Extracts from Mediterranean Ethnomedicinal Plants on Human Cancer Cell Lines.

Pollio A, Zarrelli A, Romanucci V, Di Mauro A, Barra F, Pinto G, Crescenzi E, Roscetto E, Palumbo G.

Molecules. 2016 Mar 23;21(4):395. doi: 10.3390/molecules21040395.


Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells.

Camorani S, Crescenzi E, Colecchia D, Carpentieri A, Amoresano A, Fedele M, Chiariello M, Cerchia L.

Oncotarget. 2015 Nov 10;6(35):37570-87. doi: 10.18632/oncotarget.6066.


Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.

Esposito D, Crescenzi E, Sagar V, Loreni F, Russo A, Russo G.

Oncotarget. 2014 Nov 30;5(22):11737-51.


Lactobacillus gasseri SF1183 affects intestinal epithelial cell survival and growth.

Di Luccia B, Manzo N, Baccigalupi L, Calabrò V, Crescenzi E, Ricca E, Pollice A.

PLoS One. 2013 Jul 23;8(7):e69102. doi: 10.1371/journal.pone.0069102. Print 2013.


Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.

Crescenzi E, Raia Z, Pacifico F, Mellone S, Moscato F, Palumbo G, Leonardi A.

J Biol Chem. 2013 Jun 7;288(23):16212-24. doi: 10.1074/jbc.M112.435149. Epub 2013 Apr 23.


A biochemical and cellular approach to explore the antiproliferative and prodifferentiative activity of Aloe arborescens leaf extract.

Di Luccia B, Manzo N, Vivo M, Galano E, Amoresano A, Crescenzi E, Pollice A, Tudisco R, Infascelli F, Calabrò V.

Phytother Res. 2013 Dec;27(12):1819-28. doi: 10.1002/ptr.4939. Epub 2013 Feb 17.


Senescence and NFκB: A trojan horse in tumors?

Crescenzi E, De Palma R, Leonardi A.

Oncoimmunology. 2012 Dec 1;1(9):1594-1597.


Human rpL3 induces G₁/S arrest or apoptosis by modulating p21 (waf1/cip1) levels in a p53-independent manner.

Russo A, Esposito D, Catillo M, Pietropaolo C, Crescenzi E, Russo G.

Cell Cycle. 2013 Jan 1;12(1):76-87. doi: 10.4161/cc.22963. Epub 2012 Dec 19.


Nuclear factor-{kappa}B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a.

Pacifico F, Crescenzi E, Mellone S, Iannetti A, Porrino N, Liguoro D, Moscato F, Grieco M, Formisano S, Leonardi A.

J Clin Endocrinol Metab. 2010 Mar;95(3):1421-30. doi: 10.1210/jc.2009-1128. Epub 2010 Jan 8.


The neutrophil gelatinase-associated lipocalin (NGAL), a NF-kappaB-regulated gene, is a survival factor for thyroid neoplastic cells.

Iannetti A, Pacifico F, Acquaviva R, Lavorgna A, Crescenzi E, Vascotto C, Tell G, Salzano AM, Scaloni A, Vuttariello E, Chiappetta G, Formisano S, Leonardi A.

Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14058-63. doi: 10.1073/pnas.0710846105. Epub 2008 Sep 3.


Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.

Crescenzi E, Palumbo G, de Boer J, Brady HJ.

Clin Cancer Res. 2008 Mar 15;14(6):1877-87. doi: 10.1158/1078-0432.CCR-07-4298.


RbAp48 is a target of nuclear factor-kappaB activity in thyroid cancer.

Pacifico F, Paolillo M, Chiappetta G, Crescenzi E, Arena S, Scaloni A, Monaco M, Vascotto C, Tell G, Formisano S, Leonardi A.

J Clin Endocrinol Metab. 2007 Apr;92(4):1458-66. Epub 2007 Jan 23.


Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells.

Laezza C, Pisanti S, Crescenzi E, Bifulco M.

FEBS Lett. 2006 Nov 13;580(26):6076-82. Epub 2006 Oct 12.

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