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Items: 1 to 20 of 58

1.

Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma.

Hawkins AG, Julian CM, Konzen S, Treichel S, Lawlor ER, Bailey KM.

Neoplasia. 2019 Oct;21(10):1063-1072. doi: 10.1016/j.neo.2019.08.007. Epub 2019 Sep 13.

2.

Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation.

Pfaltzgraff ER, Apfelbaum A, Kassa AP, Song JY, Jiang W, Suhan TK, Wellik DM, Lawlor ER.

Cancers (Basel). 2019 Mar 6;11(3). pii: E313. doi: 10.3390/cancers11030313.

3.

Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma.

Briski LM, Thomas DG, Patel RM, Lawlor ER, Chugh R, McHugh JB, Lucas DR.

Rare Tumors. 2018 Nov 25;10:2036361318813431. doi: 10.1177/2036361318813431. eCollection 2018.

4.

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.

Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL.

Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11.

5.

Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.

Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR.

Nature. 2018 Jul;559(7715):E11. doi: 10.1038/s41586-018-0230-z.

PMID:
29950716
6.

Utilization of Ultrasound Guided Tissue-directed Cellular Implantation for the Establishment of Biologically Relevant Metastatic Tumor Xenografts.

Thomas TT, Chukkapalli S, Van Noord RA, Krook M, Hoenerhoff MJ, Dillman JR, Lawlor ER, Opipari VP, Newman EA.

J Vis Exp. 2018 May 25;(135). doi: 10.3791/57558.

7.

Menin regulates the serine biosynthetic pathway in Ewing sarcoma.

Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.

J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28.

8.

EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.

Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR.

Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Erratum in: Nature. 2018 Jun 27;:.

9.

The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling.

Hawkins AG, Basrur V, da Veiga Leprevost F, Pedersen E, Sperring C, Nesvizhskii AI, Lawlor ER.

Mol Cell Proteomics. 2018 May;17(5):901-912. doi: 10.1074/mcp.RA118.000596. Epub 2018 Jan 31.

10.

Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.

Newman EA, Chukkapalli S, Bashllari D, Thomas TT, Van Noord RA, Lawlor ER, Hoenerhoff MJ, Opipari AW, Opipari VP.

Cell Death Dis. 2017 Dec 13;8(12):3208. doi: 10.1038/s41419-017-0004-9.

11.

Tissue-directed Implantation Using Ultrasound Visualization for Development of Biologically Relevant Metastatic Tumor Xenografts.

VAN Noord RA, Thomas T, Krook M, Chukkapalli S, Hoenerhoff MJ, Dillman JR, Lawlor ER, Opipari VP, Newman EA.

In Vivo. 2017 Sep-Oct;31(5):779-791.

12.

Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.

Svoboda LK, Bailey N, Van Noord RA, Krook MA, Harris A, Cramer C, Jasman B, Patel RM, Thomas D, Borkin D, Cierpicki T, Grembecka J, Lawlor ER.

Oncotarget. 2017 Jan 3;8(1):458-471. doi: 10.18632/oncotarget.13444.

13.

Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.

Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR.

Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11.

14.

BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization.

Gray F, Cho HJ, Shukla S, He S, Harris A, Boytsov B, Jaremko Ł, Jaremko M, Demeler B, Lawlor ER, Grembecka J, Cierpicki T.

Nat Commun. 2016 Nov 9;7:13343. doi: 10.1038/ncomms13343.

15.

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.

Evelyn CR, Lisabeth EM, Wade SM, Haak AJ, Johnson CN, Lawlor ER, Neubig RR.

Microarrays (Basel). 2016 May 28;5(2). pii: E13. doi: 10.3390/microarrays5020013.

16.

Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma.

Bailey KM, Airik M, Krook MA, Pedersen EA, Lawlor ER.

Neoplasia. 2016 Aug;18(8):480-8. doi: 10.1016/j.neo.2016.06.008.

17.

A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma.

Krook MA, Hawkins AG, Patel RM, Lucas DR, Van Noord R, Chugh R, Lawlor ER.

Oncotarget. 2016 Sep 20;7(38):61775-61788. doi: 10.18632/oncotarget.11240.

18.

Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States.

Pedersen EA, Menon R, Bailey KM, Thomas DG, Van Noord RA, Tran J, Wang H, Qu PP, Hoering A, Fearon ER, Chugh R, Lawlor ER.

Cancer Res. 2016 Sep 1;76(17):5040-53. doi: 10.1158/0008-5472.CAN-15-3422. Epub 2016 Jun 30.

19.

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma.

von Heyking K, Roth L, Ertl M, Schmidt O, Calzada-Wack J, Neff F, Lawlor ER, Burdach S, Richter GH.

Oncotarget. 2016 Jul 5;7(27):41767-41780. doi: 10.18632/oncotarget.9702.

20.

Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: A report from the Children's Oncology Group.

Cash T, McIlvaine E, Krailo MD, Lessnick SL, Lawlor ER, Laack N, Sorger J, Marina N, Grier HE, Granowetter L, Womer RB, DuBois SG.

Pediatr Blood Cancer. 2016 Oct;63(10):1771-9. doi: 10.1002/pbc.26096. Epub 2016 Jun 14.

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