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Items: 1 to 20 of 49

1.

From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data.

Ivanisevic J, Want EJ.

Metabolites. 2019 Dec 17;9(12). pii: E308. doi: 10.3390/metabo9120308. Review.

2.

Microdialysis Workflow for Metabotyping Superficial Pathologies: Application to Burn Injury.

Friston D, Laycock H, Nagy I, Want EJ.

Anal Chem. 2019 May 21;91(10):6541-6548. doi: 10.1021/acs.analchem.8b05615. Epub 2019 May 11.

3.

Determinants of the urinary and serum metabolome in children from six European populations.

Lau CE, Siskos AP, Maitre L, Robinson O, Athersuch TJ, Want EJ, Urquiza J, Casas M, Vafeiadi M, Roumeliotaki T, McEachan RRC, Azad R, Haug LS, Meltzer HM, Andrusaityte S, Petraviciene I, Grazuleviciene R, Thomsen C, Wright J, Slama R, Chatzi L, Vrijheid M, Keun HC, Coen M.

BMC Med. 2018 Nov 8;16(1):202. doi: 10.1186/s12916-018-1190-8.

4.

Development of a novel UHPLC-MS/MS-based platform to quantify amines, amino acids and methylarginines for applications in human disease phenotyping.

Ahmetaj-Shala B, Olanipekun M, Tesfai A, MacCallum N, Kirkby NS, Quinlan GJ, Shih CC, Kawai R, Mumby S, Paul-Clark M, Want EJ, Mitchell JA.

Sci Rep. 2018 Sep 18;8(1):13987. doi: 10.1038/s41598-018-31055-8.

5.

Metabolic perturbations associated with the consumption of a ketogenic medium-chain TAG diet in dogs with idiopathic epilepsy.

Law TH, Volk HA, Pan Y, Zanghi B, Want EJ.

Br J Nutr. 2018 Sep;120(5):484-490. doi: 10.1017/S0007114518001617. Epub 2018 Jul 13.

6.

LC-MS Untargeted Analysis.

Want EJ.

Methods Mol Biol. 2018;1738:99-116. doi: 10.1007/978-1-4939-7643-0_7.

PMID:
29654585
7.

Assessment of metabolic phenotypic variability in children's urine using 1H NMR spectroscopy.

Maitre L, Lau CE, Vizcaino E, Robinson O, Casas M, Siskos AP, Want EJ, Athersuch T, Slama R, Vrijheid M, Keun HC, Coen M.

Sci Rep. 2017 Apr 19;7:46082. doi: 10.1038/srep46082.

8.

Global metabolic changes induced by plant-derived pyrrolizidine alkaloids following a human poisoning outbreak and in a mouse model.

Robinson O, Toledano MB, Sands C, Beckonert O, J Want E, Goldin R, Hauser ML, Fenwick A, Thursz MR, Coen M.

Toxicol Res (Camb). 2016 Aug 12;5(6):1594-1603. doi: 10.1039/c6tx00221h. eCollection 2016 Nov 1.

9.

Plasma Lipid Profiling in a Rat Model of Hepatocellular Carcinoma: Potential Modulation Through Quinolone Administration.

Shariff MI, Tognarelli JM, Lewis MR, Want EJ, Mohamed Fel Z, Ladep NG, Crossey MM, Khan SA, Jalan R, Holmes E, Taylor-Robinson SD.

J Clin Exp Hepatol. 2015 Dec;5(4):286-94. doi: 10.1016/j.jceh.2015.07.205. Epub 2015 Jul 18.

10.

Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis.

McPhail MJW, Shawcross DL, Lewis MR, Coltart I, Want EJ, Antoniades CG, Veselkov K, Triantafyllou E, Patel V, Pop O, Gomez-Romero M, Kyriakides M, Zia R, Abeles RD, Crossey MME, Jassem W, O'Grady J, Heaton N, Auzinger G, Bernal W, Quaglia A, Coen M, Nicholson JK, Wendon JA, Holmes E, Taylor-Robinson SD.

J Hepatol. 2016 May;64(5):1058-1067. doi: 10.1016/j.jhep.2016.01.003. Epub 2016 Jan 18.

11.

Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling.

Anwar MA, Vorkas PA, Li JV, Shalhoub J, Want EJ, Davies AH, Holmes E.

Analyst. 2015 Nov 21;140(22):7586-97. doi: 10.1039/c5an01041a.

12.

Perturbations in fatty acid metabolism and apoptosis are manifested in calcific coronary artery disease: An exploratory lipidomic study.

Vorkas PA, Isaac G, Holmgren A, Want EJ, Shockcor JP, Holmes E, Henein MY.

Int J Cardiol. 2015 Oct 15;197:192-9. doi: 10.1016/j.ijcard.2015.06.048. Epub 2015 Jun 23.

PMID:
26142205
13.

Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model.

Wesseling H, Want EJ, Guest PC, Rahmoune H, Holmes E, Bahn S.

J Proteome Res. 2015 Aug 7;14(8):3174-87. doi: 10.1021/acs.jproteome.5b00105. Epub 2015 Jun 30.

14.

Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease.

Vorkas PA, Isaac G, Anwar MA, Davies AH, Want EJ, Nicholson JK, Holmes E.

Anal Chem. 2015 Apr 21;87(8):4184-93. doi: 10.1021/ac503775m. Epub 2015 Apr 8.

15.

Metabolic phenotyping of atherosclerotic plaques reveals latent associations between free cholesterol and ceramide metabolism in atherogenesis.

Vorkas PA, Shalhoub J, Isaac G, Want EJ, Nicholson JK, Holmes E, Davies AH.

J Proteome Res. 2015 Mar 6;14(3):1389-99. doi: 10.1021/pr5009898. Epub 2015 Feb 23.

16.

Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention.

Miller JA, Pappan K, Thompson PA, Want EJ, Siskos AP, Keun HC, Wulff J, Hu C, Lang JE, Chow HH.

Cancer Prev Res (Phila). 2015 Jan;8(1):86-93. doi: 10.1158/1940-6207.CAPR-14-0100. Epub 2014 Nov 11.

17.

Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae.

Gabrieli P, Kakani EG, Mitchell SN, Mameli E, Want EJ, Mariezcurrena Anton A, Serrao A, Baldini F, Catteruccia F.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16353-8. doi: 10.1073/pnas.1410488111. Epub 2014 Nov 3.

18.

The human early-life exposome (HELIX): project rationale and design.

Vrijheid M, Slama R, Robinson O, Chatzi L, Coen M, van den Hazel P, Thomsen C, Wright J, Athersuch TJ, Avellana N, Basagaña X, Brochot C, Bucchini L, Bustamante M, Carracedo A, Casas M, Estivill X, Fairley L, van Gent D, Gonzalez JR, Granum B, Gražulevičienė R, Gutzkow KB, Julvez J, Keun HC, Kogevinas M, McEachan RR, Meltzer HM, Sabidó E, Schwarze PE, Siroux V, Sunyer J, Want EJ, Zeman F, Nieuwenhuijsen MJ.

Environ Health Perspect. 2014 Jun;122(6):535-44. doi: 10.1289/ehp.1307204. Epub 2014 Mar 7.

19.

Systems biology of human atherosclerosis.

Shalhoub J, Sikkel MB, Davies KJ, Vorkas PA, Want EJ, Davies AH.

Vasc Endovascular Surg. 2014 Jan;48(1):5-17. doi: 10.1177/1538574413510628. Epub 2013 Nov 7. Review.

PMID:
24212404
20.

Global metabolic profiling of animal and human tissues via UPLC-MS.

Want EJ, Masson P, Michopoulos F, Wilson ID, Theodoridis G, Plumb RS, Shockcor J, Loftus N, Holmes E, Nicholson JK.

Nat Protoc. 2013 Jan;8(1):17-32. doi: 10.1038/nprot.2012.135. Epub 2012 Dec 6.

PMID:
23222455

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