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Items: 1 to 20 of 26


Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging.

Grippin AJ, Wummer B, Wildes T, Dyson K, Trivedi V, Yang C, Sebastian M, Mendez-Gomez HR, Padala S, Grubb M, Fillingim M, Monsalve A, Sayour EJ, Dobson J, Mitchell DA.

ACS Nano. 2019 Dec 24;13(12):13884-13898. doi: 10.1021/acsnano.9b05037. Epub 2019 Dec 2.


Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma.

Long Y, Tao H, Karachi A, Grippin AJ, Jin L, Chang YE, Zhang W, Dyson KA, Hou AY, Na M, Deleyrolle LP, Sayour EJ, Rahman M, Mitchell DA, Lin Z, Huang J.

Cancer Res. 2019 Nov 13. pii: canres.1577.2019. doi: 10.1158/0008-5472.CAN-19-1577. [Epub ahead of print]


CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors.

Jin L, Tao H, Karachi A, Long Y, Hou AY, Na M, Dyson KA, Grippin AJ, Deleyrolle LP, Zhang W, Rajon DA, Wang QJ, Yang JC, Kresak JL, Sayour EJ, Rahman M, Bova FJ, Lin Z, Mitchell DA, Huang J.

Nat Commun. 2019 Sep 5;10(1):4016. doi: 10.1038/s41467-019-11869-4.


Emerging trends in immunotherapy for pediatric sarcomas.

Dyson KA, Stover BD, Grippin A, Mendez-Gomez HR, Lagmay J, Mitchell DA, Sayour EJ.

J Hematol Oncol. 2019 Jul 16;12(1):78. doi: 10.1186/s13045-019-0756-z. Review.


Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition.

Karachi A, Yang C, Dastmalchi F, Sayour EJ, Huang J, Azari H, Long Y, Flores C, Mitchell DA, Rahman M.

Neuro Oncol. 2019 Jun 10;21(6):730-741. doi: 10.1093/neuonc/noz015.


RNA-Modified T Cells Mediate Effective Delivery of Immunomodulatory Cytokines to Brain Tumors.

Pohl-GuimarĂ£es F, Yang C, Dyson KA, Wildes TJ, Drake J, Huang J, Flores C, Sayour EJ, Mitchell DA.

Mol Ther. 2019 Apr 10;27(4):837-849. doi: 10.1016/j.ymthe.2018.10.007. Epub 2018 Oct 17.


Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma.

Hoang-Minh LB, Siebzehnrubl FA, Yang C, Suzuki-Hatano S, Dajac K, Loche T, Andrews N, Schmoll Massari M, Patel J, Amin K, Vuong A, Jimenez-Pascual A, Kubilis P, Garrett TJ, Moneypenny C, Pacak CA, Huang J, Sayour EJ, Mitchell DA, Sarkisian MR, Reynolds BA, Deleyrolle LP.

EMBO J. 2018 Dec 3;37(23). pii: e98772. doi: 10.15252/embj.201798772. Epub 2018 Oct 15.


Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy.

Sayour EJ, Grippin A, De Leon G, Stover B, Rahman M, Karachi A, Wummer B, Moore G, Castillo-Caro P, Fredenburg K, Sarkisian MR, Huang J, Deleyrolle LP, Sahay B, Carrera-Justiz S, Mendez-Gomez HR, Mitchell DA.

Nano Lett. 2018 Oct 10;18(10):6195-6206. doi: 10.1021/acs.nanolett.8b02179. Epub 2018 Sep 27.


Cancer Vaccine Immunotherapy with RNA-Loaded Liposomes.

Sayour EJ, Mendez-Gomez HR, Mitchell DA.

Int J Mol Sci. 2018 Sep 23;19(10). pii: E2890. doi: 10.3390/ijms19102890. Review.


The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas.

Mu L, Long Y, Yang C, Jin L, Tao H, Ge H, Chang YE, Karachi A, Kubilis PS, De Leon G, Qi J, Sayour EJ, Mitchell DA, Lin Z, Huang J.

Front Mol Neurosci. 2018 Mar 28;11:82. doi: 10.3389/fnmol.2018.00082. eCollection 2018.


CD4+ and Perivascular Foxp3+ T Cells in Glioma Correlate with Angiogenesis and Tumor Progression.

Mu L, Yang C, Gao Q, Long Y, Ge H, DeLeon G, Jin L, Chang YE, Sayour EJ, Ji J, Jiang J, Kubilis PS, Qi J, Gu Y, Wang J, Song Y, Mitchell DA, Lin Z, Huang J.

Front Immunol. 2017 Nov 7;8:1451. doi: 10.3389/fimmu.2017.01451. eCollection 2017.


Translational nanoparticle engineering for cancer vaccines.

Grippin AJ, Sayour EJ, Mitchell DA.

Oncoimmunology. 2017 Feb 22;6(10):e1290036. doi: 10.1080/2162402X.2017.1290036. eCollection 2017. Review.


Immunotherapy for Pediatric Brain Tumors.

Sayour EJ, Mitchell DA.

Brain Sci. 2017 Oct 21;7(10). pii: E137. doi: 10.3390/brainsci7100137. Review.


CD70, a novel target of CAR T-cell therapy for gliomas.

Jin L, Ge H, Long Y, Yang C, Chang YE, Mu L, Sayour EJ, De Leon G, Wang QJ, Yang JC, Kubilis PS, Bao H, Xia S, Lu D, Kong Y, Hu L, Shang Y, Jiang C, Nie J, Li S, Gu Y, Sun J, Mitchell DA, Lin Z, Huang J.

Neuro Oncol. 2018 Jan 10;20(1):55-65. doi: 10.1093/neuonc/nox116.


Manipulation of Innate and Adaptive Immunity through Cancer Vaccines.

Sayour EJ, Mitchell DA.

J Immunol Res. 2017;2017:3145742. doi: 10.1155/2017/3145742. Epub 2017 Feb 6. Review.


Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles.

Sayour EJ, De Leon G, Pham C, Grippin A, Kemeny H, Chua J, Huang J, Sampson JH, Sanchez-Perez L, Flores C, Mitchell DA.

Oncoimmunology. 2016 Nov 18;6(1):e1256527. doi: 10.1080/2162402X.2016.1256527. eCollection 2017.


Bone marrow transplantation for CVID-like humoral immune deficiency associated with red cell aplasia.

Sayour EJ, Mousallem T, Van Mater D, Wang E, Martin P, Buckley RH, Barfield RC.

Pediatr Blood Cancer. 2016 Oct;63(10):1856-9. doi: 10.1002/pbc.26092. Epub 2016 Jun 8.


FGFR1 N546K and H3F3A K27M mutations in a diffuse leptomeningeal tumour with glial and neuronal markers.

Dyson K, Rivera-Zengotita M, Kresak J, Weaver K, Stover B, Fort J, Rahman M, Pincus DW, Sayour EJ.

Histopathology. 2016 Oct;69(4):704-7. doi: 10.1111/his.12983. Epub 2016 Jul 4. No abstract available.


Serum elevation of B lymphocyte stimulator does not increase regulatory B cells in glioblastoma patients undergoing immunotherapy.

Saraswathula A, Reap EA, Choi BD, Schmittling RJ, Norberg PK, Sayour EJ, Herndon JE 2nd, Healy P, Congdon KL, Archer GE, Sanchez-Perez L, Sampson JH.

Cancer Immunol Immunother. 2016 Feb;65(2):205-11. doi: 10.1007/s00262-015-1784-3. Epub 2016 Jan 12.


Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.

Pham CD, Flores C, Yang C, Pinheiro EM, Yearley JH, Sayour EJ, Pei Y, Moore C, McLendon RE, Huang J, Sampson JH, Wechsler-Reya R, Mitchell DA.

Clin Cancer Res. 2016 Feb 1;22(3):582-95. doi: 10.1158/1078-0432.CCR-15-0713. Epub 2015 Sep 24.

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