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Items: 1 to 20 of 24

1.

A Combination of Rosa Canina Extracts and Gold Complex Favors Apoptosis of Caco-2 Cells by Increasing Oxidative Stress and Mitochondrial Dysfunction.

Mármol I, Jiménez-Moreno N, Ancín-Azpilicueta C, Osada J, Cerrada E, Rodríguez-Yoldi MJ.

Antioxidants (Basel). 2019 Dec 24;9(1). pii: E17. doi: 10.3390/antiox9010017.

2.

Alkynyl Gold(I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer.

Mármol I, Castellnou P, Alvarez R, Gimeno MC, Rodríguez-Yoldi MJ, Cerrada E.

Eur J Med Chem. 2019 Dec 1;183:111661. doi: 10.1016/j.ejmech.2019.111661. Epub 2019 Sep 7.

PMID:
31546196
3.

Gold as a Possible Alternative to Platinum-Based Chemotherapy for Colon Cancer Treatment.

Mármol I, Quero J, Rodríguez-Yoldi MJ, Cerrada E.

Cancers (Basel). 2019 Jun 5;11(6). pii: E780. doi: 10.3390/cancers11060780. Review.

4.

Role of PTA in the prevention of Cu(amyloid-β) induced ROS formation and amyloid-β oligomerisation in the presence of Zn.

Atrián-Blasco E, Cerrada E, Faller P, Laguna M, Hureau C.

Metallomics. 2019 Jun 19;11(6):1154-1161. doi: 10.1039/c9mt00011a.

5.

Proteasome versus Thioredoxin Reductase Competition as Possible Biological Targets in Antitumor Mixed Thiolate-Dithiocarbamate Gold(III) Complexes.

Quero J, Cabello S, Fuertes T, Mármol I, Laplaza R, Polo V, Gimeno MC, Rodriguez-Yoldi MJ, Cerrada E.

Inorg Chem. 2018 Sep 4;57(17):10832-10845. doi: 10.1021/acs.inorgchem.8b01464. Epub 2018 Aug 17.

PMID:
30117739
6.

Alkynyl gold(I) complex triggers necroptosis via ROS generation in colorectal carcinoma cells.

Mármol I, Virumbrales-Muñoz M, Quero J, Sánchez-de-Diego C, Fernández L, Ochoa I, Cerrada E, Yoldi MJR.

J Inorg Biochem. 2017 Nov;176:123-133. doi: 10.1016/j.jinorgbio.2017.08.020. Epub 2017 Aug 31.

PMID:
28892675
7.

Novel Gold(I) Thiolate Derivatives Synergistic with 5-Fluorouracil as Potential Selective Anticancer Agents in Colon Cancer.

Atrián-Blasco E, Gascón S, Rodrı Guez-Yoldi MJ, Laguna M, Cerrada E.

Inorg Chem. 2017 Jul 17;56(14):8562-8579. doi: 10.1021/acs.inorgchem.7b01370. Epub 2017 Jul 6.

PMID:
28682069
8.

Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer.

Mármol I, Sánchez-de-Diego C, Pradilla Dieste A, Cerrada E, Rodriguez Yoldi MJ.

Int J Mol Sci. 2017 Jan 19;18(1). pii: E197. doi: 10.3390/ijms18010197. Review.

9.

The anticancer effect related to disturbances in redox balance on Caco-2 cells caused by an alkynyl gold(I) complex.

Sánchez-de-Diego C, Mármol I, Pérez R, Gascón S, Rodriguez-Yoldi MJ, Cerrada E.

J Inorg Biochem. 2017 Jan;166:108-121. doi: 10.1016/j.jinorgbio.2016.11.009. Epub 2016 Nov 4.

PMID:
27842247
10.

In vitro and in vivo evaluation of organometallic gold(I) derivatives as anticancer agents.

García-Moreno E, Tomás A, Atrián-Blasco E, Gascón S, Romanos E, Rodriguez-Yoldi MJ, Cerrada E, Laguna M.

Dalton Trans. 2016 Feb 14;45(6):2462-75. doi: 10.1039/c5dt01802a. Epub 2015 Oct 15.

PMID:
26469679
11.

In Vivo Anticancer Activity, Toxicology and Histopathological Studies of the Thiolate Gold(I) Complex [Au(Spyrimidine)(PTA-CH2Ph)]Br.

García-Moreno E, Gascón S, García de Jalón JA, Romanos E, Rodriguez-Yoldi MJ, Cerrada E, Laguna M.

Anticancer Agents Med Chem. 2015;15(6):773-82.

PMID:
25634450
12.

Gold(I) complexes with alkylated PTA (1,3,5-triaza-7-phosphaadamantane) phosphanes as anticancer metallodrugs.

García-Moreno E, Gascón S, Atrián-Blasco E, Rodriguez-Yoldi MJ, Cerrada E, Laguna M.

Eur J Med Chem. 2014 May 22;79:164-72. doi: 10.1016/j.ejmech.2014.04.001. Epub 2014 Apr 1.

PMID:
24732792
13.

trans-thionate derivatives of Pt(II) and Pd(II) with water-soluble phosphane PTA and DAPTA ligands: antiproliferative activity against human ovarian cancer cell lines.

Guerrero E, Miranda S, Lüttenberg S, Fröhlich N, Koenen JM, Mohr F, Cerrada E, Laguna M, Mendía A.

Inorg Chem. 2013 Jun 3;52(11):6635-47. doi: 10.1021/ic4006746. Epub 2013 May 21.

PMID:
23692403
14.

Thiolato gold(I) complexes containing water-soluble phosphane ligands: a characterization of their chemical and biological properties.

Vergara E, Cerrada E, Clavel C, Casini A, Laguna M.

Dalton Trans. 2011 Nov 7;40(41):10927-35. doi: 10.1039/c1dt10892a. Epub 2011 Sep 9.

PMID:
21904768
15.

Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands.

Vergara E, Casini A, Sorrentino F, Zava O, Cerrada E, Rigobello MP, Bindoli A, Laguna M, Dyson PJ.

ChemMedChem. 2010 Jan;5(1):96-102. doi: 10.1002/cmdc.200900370.

PMID:
19937669
16.

S,C- and S,S-coupling via dithiolate transfer reactions from tin to nickel complexes.

Cerrada E, Moreno A, Laguna M.

Dalton Trans. 2009 Sep 14;(34):6825-35. doi: 10.1039/b902569c. Epub 2009 Jul 15.

PMID:
19690695
17.

Novel dithiolene complexes incorporating conjugated electroactive ligands.

Skabara PJ, Pozo-Gonzalo C, Lardiés Miazza N, Laguna M, Cerrada E, Luquin A, González B, Coles SJ, Hursthouse MB, Harrington RW, Clegg W.

Dalton Trans. 2008 Jun 21;(23):3070-9. doi: 10.1039/b801187g. Epub 2008 May 7.

PMID:
18521449
19.

Synthesis and properties of alkynethiolate gold(I) complexes.

Lardiés N, Romeo I, Cerrada E, Laguna M, Skabara PJ.

Dalton Trans. 2007 Dec 7;(45):5329-38.

PMID:
18271490
20.

Synthesis and coordination chemistry of an alkyne functionalised bis(pyrazolyl)methane ligand.

Mohr F, Cerrada E, Laguna M.

Dalton Trans. 2006 Dec 21;(47):5567-73. Epub 2006 Oct 24.

PMID:
17225893

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