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Items: 1 to 20 of 33


Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples.

Scott EM, Jacobus EJ, Lyons B, Frost S, Freedman JD, Dyer A, Khalique H, Taverner WK, Carr A, Champion BR, Fisher KD, Seymour LW, Duffy MR.

J Immunother Cancer. 2019 Nov 21;7(1):320. doi: 10.1186/s40425-019-0807-6.


Use of Liquid Patient Ascites Fluids as a Preclinical Model for Oncolytic Virus Activity.

Scott EM, Frost S, Khalique H, Freedman JD, Seymour LW, Lei-Rossmann J.

Methods Mol Biol. 2020;2058:261-270. doi: 10.1007/978-1-4939-9794-7_17.


Response to Comment on Law et al. Suboptimal Nocturnal Glucose Control Is Associated With Large for Gestational Age in Treated Gestational Diabetes Mellitus. Diabetes Care 2019;42:810-815.

Law GR, Alnaji A, Alrefaii L, Endersby D, Cartland SJ, Gilbey SG, Jennings PE, Murphy HR, Scott EM.

Diabetes Care. 2019 Jul;42(7):e123-e124. doi: 10.2337/dci19-0018. No abstract available.


Suboptimal Nocturnal Glucose Control Is Associated With Large for Gestational Age in Treated Gestational Diabetes Mellitus.

Law GR, Alnaji A, Alrefaii L, Endersby D, Cartland SJ, Gilbey SG, Jennings PE, Murphy HR, Scott EM.

Diabetes Care. 2019 May;42(5):810-815. doi: 10.2337/dc18-2212. Epub 2019 Feb 14.


Antagonism of Glycolysis and Reductive Carboxylation of Glutamine Potentiates Activity of Oncolytic Adenoviruses in Cancer Cells.

Dyer A, Schoeps B, Frost S, Jakeman P, Scott EM, Freedman J, Jacobus EJ, Seymour LW.

Cancer Res. 2019 Jan 15;79(2):331-345. doi: 10.1158/0008-5472.CAN-18-1326. Epub 2018 Nov 28.


An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells.

Freedman JD, Duffy MR, Lei-Rossmann J, Muntzer A, Scott EM, Hagel J, Campo L, Bryant RJ, Verrill C, Lambert A, Miller P, Champion BR, Seymour LW, Fisher KD.

Cancer Res. 2018 Dec 15;78(24):6852-6865. doi: 10.1158/0008-5472.CAN-18-1750. Epub 2018 Nov 18.


Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.

Cancer Gene Ther. 2019 Mar;26(3-4):59-73. doi: 10.1038/s41417-018-0042-1. Epub 2018 Sep 4.


Exploring the Feasibility of Use of An Online Dietary Assessment Tool (myfood24) in Women with Gestational Diabetes.

Gianfrancesco C, Darwin Z, McGowan L, Smith DM, Haddrill R, Carter M, Scott EM, Alwan NA, Morris MA, Albar SA, Cade JE.

Nutrients. 2018 Aug 23;10(9). pii: E1147. doi: 10.3390/nu10091147.


Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial.

Stewart ZA, Wilinska ME, Hartnell S, O'Neil LK, Rayman G, Scott EM, Barnard K, Farrington C, Hovorka R, Murphy HR.

Diabetes Care. 2018 Jul;41(7):1391-1399. doi: 10.2337/dc17-2534. Epub 2018 Mar 13.


Accuracy, User Acceptability, and Safety Evaluation for the FreeStyle Libre Flash Glucose Monitoring System When Used by Pregnant Women with Diabetes.

Scott EM, Bilous RW, Kautzky-Willer A.

Diabetes Technol Ther. 2018 Mar;20(3):180-188. doi: 10.1089/dia.2017.0386. Epub 2018 Feb 22.


Solid Tumor Immunotherapy with T Cell Engager-Armed Oncolytic Viruses.

Scott EM, Duffy MR, Freedman JD, Fisher KD, Seymour LW.

Macromol Biosci. 2018 Jan;18(1). doi: 10.1002/mabi.201700187. Epub 2017 Sep 13. Review.


Oncolytic adenovirus expressing bispecific antibody targets T-cell cytotoxicity in cancer biopsies.

Freedman JD, Hagel J, Scott EM, Psallidas I, Gupta A, Spiers L, Miller P, Kanellakis N, Ashfield R, Fisher KD, Duffy MR, Seymour LW.

EMBO Mol Med. 2017 Aug;9(8):1067-1087. doi: 10.15252/emmm.201707567.


Translating HbA1c measurements into estimated average glucose values in pregnant women with diabetes.

Law GR, Gilthorpe MS, Secher AL, Temple R, Bilous R, Mathiesen ER, Murphy HR, Scott EM.

Diabetologia. 2017 Apr;60(4):618-624. doi: 10.1007/s00125-017-4205-7. Epub 2017 Jan 19.


Closed-Loop Insulin Delivery during Pregnancy in Women with Type 1 Diabetes.

Stewart ZA, Wilinska ME, Hartnell S, Temple RC, Rayman G, Stanley KP, Simmons D, Law GR, Scott EM, Hovorka R, Murphy HR.

N Engl J Med. 2016 Aug 18;375(7):644-54. doi: 10.1056/NEJMoa1602494.


The role of sleep duration in diabetes and glucose control.

Alnaji A, Law GR, Scott EM.

Proc Nutr Soc. 2016 Nov;75(4):512-520. Epub 2016 Jun 23.


Overcoming Barriers in Oncolytic Virotherapy with HDAC Inhibitors and Immune Checkpoint Blockade.

Marchini A, Scott EM, Rommelaere J.

Viruses. 2016 Jan 6;8(1). pii: E9. doi: 10.3390/v8010009. Review.


Analysis of Continuous Glucose Monitoring in Pregnant Women With Diabetes: Distinct Temporal Patterns of Glucose Associated With Large-for-Gestational-Age Infants.

Law GR, Ellison GT, Secher AL, Damm P, Mathiesen ER, Temple R, Murphy HR, Scott EM.

Diabetes Care. 2015 Jul;38(7):1319-25. doi: 10.2337/dc15-0070. Epub 2015 Apr 23.


Oncolytic parvoviruses: from basic virology to clinical applications.

Marchini A, Bonifati S, Scott EM, Angelova AL, Rommelaere J.

Virol J. 2015 Jan 29;12:6. doi: 10.1186/s12985-014-0223-y. Review.


Circadian rhythms, insulin action, and glucose homeostasis.

Tan E, Scott EM.

Curr Opin Clin Nutr Metab Care. 2014 Jul;17(4):343-8. doi: 10.1097/MCO.0000000000000061. Review.


Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm.

Prasai MJ, Mughal RS, Wheatcroft SB, Kearney MT, Grant PJ, Scott EM.

Diabetes. 2013 Jun;62(6):1981-9. doi: 10.2337/db11-1740. Epub 2013 Feb 4.

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